Department of Clinical and Translational Science

Research Output

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Review article
2020

Infarct Zone: a Novel Platform for Exosome Trade in Cardiac Tissue Regeneration

Thankam, F. G. & Agrawal, D. K., Jan 1 2020, (Accepted/In press) In : Journal of Cardiovascular Translational Research.

Research output: Contribution to journalReview article

2019

Adipokine Dysregulation and Insulin Resistance with Atherosclerotic Vascular Disease: Metabolic Syndrome or Independent Sequelae?

Satish, M., Saxena, S. K. & Agrawal, D. K., Jan 1 2019, In : Journal of Cardiovascular Translational Research.

Research output: Contribution to journalReview article

2 Scopus citations

An update on PTEN modulators–a patent review

Boosani, C. S., Gunasekar, P. & Agrawal, D. K., Nov 2 2019, In : Expert Opinion on Therapeutic Patents. 29, 11, p. 881-889 9 p.

Research output: Contribution to journalReview article

1 Scopus citations

Atherothrombosis and the NLRP3 inflammasome – endogenous mechanisms of inhibition

Satish, M. & Agrawal, D. K., Jan 1 2019, (Accepted/In press) In : Translational Research.

Research output: Contribution to journalReview article

Epigenetic mechanisms and implications in tendon inflammation (Review)

Thankam, F. G., Boosani, C. S., Dilisio, M. & Agrawal, D. K., Jan 1 2019, In : International Journal of Molecular Medicine. 43, 1, p. 3-14 12 p.

Research output: Contribution to journalReview article

1 Scopus citations

Immunopathogenesis and biomarkers of recurrent atrial fibrillation following ablation therapy in patients with preexisting atrial fibrillation

Rosenberg, J. H., Werner, J. H., Plitt, G. D., Noble, V. V., Spring, J. T., Stephens, B. A., Siddique, A., Merritt-Genore, H. L., Moulton, M. J. & Agrawal, D. K., Mar 4 2019, In : Expert Review of Cardiovascular Therapy. 17, 3, p. 193-207 15 p.

Research output: Contribution to journalReview article

1 Scopus citations

Pro-inflammatory and pro-resolving mechanisms in the immunopathology of arteriovenous fistula maturation

Satish, M., Gunasekar, P. & Agrawal, D. K., May 4 2019, In : Expert Review of Cardiovascular Therapy. 17, 5, p. 369-376 8 p.

Research output: Contribution to journalReview article

1 Scopus citations

Therapeutic potential of exosomes in rotator cuff tendon healing

Connor, D. E., Paulus, J. A., Dabestani, P. J., Thankam, F. K., Dilisio, M., Gross, R. M. & Agrawal, D. K., Jan 1 2019, In : Journal of Bone and Mineral Metabolism.

Research output: Contribution to journalReview article

4 Scopus citations
2018

Brain injury and neural stem cells

Ludwig, P. E., Thankam, F. G., Patil, A. A., Chamczuk, A. J. & Agrawal, D. K., Jan 1 2018, In : Neural Regeneration Research. 13, 1, p. 7-18 12 p.

Research output: Contribution to journalReview article

16 Scopus citations

Cell-specific histone modifications in atherosclerosis (Review)

Jiang, W., Agrawal, D. K. & Boosani, C. S., Aug 1 2018, In : Molecular Medicine Reports. 18, 2, p. 1215-1224 10 p.

Research output: Contribution to journalReview article

7 Scopus citations

Collagen I: A kingpin for rotator cuff tendon pathology

Thankam, F. G., Dilisio, M., Gross, R. M. & Agrawal, D. K., Jan 1 2018, In : American Journal of Translational Research. 10, 11, p. 3291-3309 19 p., AJTR0079000.

Research output: Contribution to journalReview article

4 Scopus citations

Delivery of viral vectors for gene therapy in intimal hyperplasia and restenosis in atherosclerotic swine

Hall, S. & Agrawal, D. K., Aug 1 2018, In : Drug Delivery and Translational Research. 8, 4, p. 918-927 10 p.

Research output: Contribution to journalReview article

3 Scopus citations

From cord to caudate: Characterizing umbilical cord blood stem cells and their paracrine interactions with the injured brain

Maillacheruvu, P. F., Engel, L. M., Crum, I. T., Agrawal, D. K. & Peeples, E. S., Jan 1 2018, In : Pediatric Research. 83, 1-2, p. 205-213 9 p.

Research output: Contribution to journalReview article

2 Scopus citations

Immunobiology of periprosthetic inflammation and pain following ultra-high-molecular-weight-polyethylene wear debris in the lumbar spine

Werner, J. H., Rosenberg, J. H., Keeley, K. L. & Agrawal, D. K., Aug 3 2018, In : Expert Review of Clinical Immunology. 14, 8, p. 695-706 12 p.

Research output: Contribution to journalReview article

Immunopathological and molecular basis of functional dyspepsia and current therapeutic approaches

Addula, M., Wilson, V. E. D., Reddymasu, S. & Agrawal, D. K., Oct 3 2018, In : Expert Review of Clinical Immunology. 14, 10, p. 831-840 10 p.

Research output: Contribution to journalReview article

Immunotherapy plus cryotherapy: Potential augmented abscopal effect for advanced cancers

Abdo, J., Cornell, D. L., Mittal, S. K. & Agrawal, D. K., Mar 28 2018, In : Frontiers in Oncology. 8, MAR, 85.

Research output: Contribution to journalReview article

23 Scopus citations

Mechanisms, diagnosis, and treatment of heart failure with preserved ejection fraction and diastolic dysfunction

Plitt, G. D., Spring, J. T., Moulton, M. J. & Agrawal, D. K., Aug 3 2018, In : Expert Review of Cardiovascular Therapy. 16, 8, p. 579-589 11 p.

Research output: Contribution to journalReview article

11 Scopus citations

Pleiotropic Anti-atherosclerotic Effects of PCSK9 InhibitorsFrom Molecular Biology to Clinical Translation

Karagiannis, A. D., Liu, M., Toth, P. P., Zhao, S., Agrawal, D. K., Libby, P. & Chatzizisis, Y. S., Apr 1 2018, In : Current Atherosclerosis Reports. 20, 4, 20.

Research output: Contribution to journalReview article

11 Scopus citations
2017

Alterations in tendon microenvironment in response to mechanical load: Potential molecular targets for treatment strategies

Fouda, M. B., Thankam, F. G., Dilisio, M. & Agrawal, D. K., 2017, In : American Journal of Translational Research. 9, 10, p. 4341-4360 20 p., AJTR0059913.

Research output: Contribution to journalReview article

7 Scopus citations

Basis for molecular diagnostics and immunotherapy for esophageal cancer

Abdo, J., Agrawal, D. K. & Mittal, S. K., Jan 2 2017, In : Expert Review of Anticancer Therapy. 17, 1, p. 33-45 13 p.

Research output: Contribution to journalReview article

9 Scopus citations

Clinical implications of high-mobility group box-1 (HMGB1) and the receptor for advanced glycation end-products (RAGE) in cutaneous malignancy: A systematic review

Nguyen, A. H., Detty, S. Q. & Agrawal, D. K., Jan 1 2017, In : Anticancer Research. 37, 1, p. 1-7 7 p.

Research output: Contribution to journalReview article

19 Scopus citations

Hormonal therapy in traumatic spinal cord injury

Ludwig, P. E., Patil, A. A., Chamczuk, A. J. & Agrawal, D. K., 2017, In : American Journal of Translational Research. 9, 9, p. 3881-3895 15 p., AJTR0057123.

Research output: Contribution to journalReview article

6 Scopus citations

Interplay of immunity and vitamin D: Interactions and implications with current IBD therapy

Abdo, J., Rai, V. & Agrawal, D. K., 2017, In : Current Medicinal Chemistry. 24, 9, p. 852-867 16 p.

Research output: Contribution to journalReview article

6 Scopus citations

Kawasaki disease: etiopathogenesis and novel treatment strategies

Agarwal, S. & Agrawal, D. K., Mar 4 2017, In : Expert Review of Clinical Immunology. 13, 3, p. 247-258 12 p.

Research output: Contribution to journalReview article

20 Scopus citations

Pain and the pathogenesis of biceps tendinopathy

Raney, E. B., Thankam, F. G., Dilisio, M. & Agrawal, D. K., 2017, In : American Journal of Translational Research. 9, 6, p. 2668-2683 16 p., AJTR0052921.

Research output: Contribution to journalReview article

9 Scopus citations

Radioprotective agents to prevent cellular damage due to ionizing radiation

Smith, T. A., Kirkpatrick, D. R., Smith, S., Smith, T. K., Pearson, T., Kailasam, A., Herrmann, K. Z., Schubert, J. & Agrawal, D. K., Nov 9 2017, In : Journal of Translational Medicine. 15, 1, 232.

Research output: Contribution to journalReview article

23 Scopus citations

Relevance of mouse models of cardiac fibrosis and hypertrophy in cardiac research

Rai, V., Sharma, P. K., Agrawal, S. & Agrawal, D. K., Jan 1 2017, In : Molecular and Cellular Biochemistry. 424, 1-2, p. 123-145 23 p.

Research output: Contribution to journalReview article

25 Scopus citations

Role of Vitamin D in Cardiovascular Diseases

Rai, V. & Agrawal, D. K., Dec 1 2017, In : Endocrinology and Metabolism Clinics of North America. 46, 4, p. 1039-1059 21 p.

Research output: Contribution to journalReview article

17 Scopus citations

Single versus combined immunoregulatory approach using PD-1 and CTLA-4 modulators in controlling sepsis

Rudick, C. P., Cornell, D. L. & Agrawal, D. K., Sep 2 2017, In : Expert Review of Clinical Immunology. 13, 9, p. 907-919 13 p.

Research output: Contribution to journalReview article

3 Scopus citations

The danger zone: Systematic review of the role of HMGB1 danger signalling in traumatic brain injury

Parker, T. M., Nguyen, A. H., Rabang, J. R., Patil, A. A. & Agrawal, D. K., Jan 2 2017, In : Brain Injury. 31, 1, p. 2-8 7 p.

Research output: Contribution to journalReview article

20 Scopus citations

The role of damage-and pathogen-associated molecular patterns in inflammation-mediated vulnerability of atherosclerotic plaques

Rai, V. & Agrawal, D. K., 2017, In : Canadian Journal of Physiology and Pharmacology. 95, 10, p. 1245-1253 9 p.

Research output: Contribution to journalReview article

19 Scopus citations

Triggering receptor expressed on myeloid cells in the pathogenesis of periodontitis: potential novel treatment strategies

Rudick, C. P., Miyamoto, T., Lang, M. S. & Agrawal, D. K., Dec 2 2017, In : Expert Review of Clinical Immunology. 13, 12, p. 1189-1197 9 p.

Research output: Contribution to journalReview article

Vitamin D and Bronchial Asthma: An Overview of Data From the Past 5 Years

Hall, S. C. & Agrawal, D. K., May 1 2017, In : Clinical Therapeutics. 39, 5, p. 917-929 13 p.

Research output: Contribution to journalReview article

29 Scopus citations

Vitamin D and Its Effects on Articular Cartilage and Osteoarthritis

Garfinkel, R. J., Dilisio, M. & Agrawal, D. K., Jun 20 2017, In : Orthopaedic Journal of Sports Medicine. 5, 6

Research output: Contribution to journalReview article

8 Scopus citations

Vitamin D receptor polymorphism and cancer: An update

Rai, V., Abdo, J., Agrawal, S. & Agrawal, D. K., Aug 1 2017, In : Anticancer Research. 37, 8, p. 3991-4003 13 p.

Research output: Contribution to journalReview article

24 Scopus citations
2016

Association of high mobility group BOX-1 and receptor for advanced glycation endproducts with clinicopathological features of haematological malignancies: A systematic review

Nguyen, A. H., Bhavsar, S. B., Riley, E. M., Caponetti, G. C. & Agrawal, D. K., 2016, In : Wspolczesna Onkologia. 20, 6, p. 425-429 5 p.

Research output: Contribution to journalReview article

3 Scopus citations

Clinical use of high mobility group box 1 and the receptor for advanced glycation end products in the prognosis and risk stratification of heart failure: A literature review

Marsh, A. M., Nguyen, A. H., Parker, T. M. & Agrawal, D. K., 2016, In : Canadian Journal of Physiology and Pharmacology. 95, 3, p. 253-259 7 p.

Research output: Contribution to journalReview article

8 Scopus citations

Clinical value of high mobility group box 1 and the receptor for advanced glycation end-products in head and neck cancer: A systematic review

Nguyen, A., Bhavsar, S., Riley, E., Caponetti, G. & Agrawal, D. K., Oct 1 2016, In : International Archives of Otorhinolaryngology. 20, 4, p. 382-389 8 p.

Research output: Contribution to journalReview article

11 Scopus citations

Effects of matrix metalloproteinases on the fate of mesenchymal stem cells

Almalki, S. G. & Agrawal, D. K., Sep 9 2016, In : Stem Cell Research and Therapy. 7, 1, 129.

Research output: Contribution to journalReview article

47 Scopus citations

Has Vitamin D had its "time in the sun" for melanoma?

Huerter, C., Vaudreuil, A., Agrawal, D. K. & Nguyen, A. H., Dec 1 2016, In : Journal of Clinical and Aesthetic Dermatology. 9, 12, p. 11-12 2 p.

Research output: Contribution to journalReview article

Immunological basis for treatment of graft versus host disease after liver transplant

Rai, V., Dietz, N. E. & Agrawal, D. K., May 3 2016, In : Expert Review of Clinical Immunology. 12, 5, p. 583-593 11 p.

Research output: Contribution to journalReview article

2 Scopus citations

Immunological basis in the pathogenesis of intrahepatic cholestasis of pregnancy

Larson, S. P., Kovilam, O. & Agrawal, D. K., Jan 2 2016, In : Expert Review of Clinical Immunology. 12, 1, p. 39-48 10 p.

Research output: Contribution to journalReview article

11 Scopus citations

Mesenchymal stem cells and cutaneous wound healing: Novel methods to increase cell delivery and therapeutic efficacy

Lee, D. E., Ayoub, N. & Agrawal, D. K., Mar 9 2016, In : Stem Cell Research and Therapy. 7, 1, 303.

Research output: Contribution to journalReview article

126 Scopus citations

Phosphatases and kinases regulating CDC25 activity in the cell cycle: clinical implications of CDC25 overexpression and potential treatment strategies

Sur, S. & Agrawal, D. K., May 1 2016, In : Molecular and Cellular Biochemistry. 416, 1-2, p. 33-46 14 p.

Research output: Contribution to journalReview article

63 Scopus citations

Role of risk stratification and genetics in sudden cardiac death

Rai, V. & Agrawal, D. K., 2016, In : Canadian Journal of Physiology and Pharmacology. 95, 3, p. 225-238 14 p.

Research output: Contribution to journalReview article

6 Scopus citations

The impact of Vitamin D on asthmatic human airway smooth muscle

Hall, S. C., Fischer, K. D. & Agrawal, D. K., Feb 1 2016, In : Expert Review of Respiratory Medicine. 10, 2, p. 127-135 9 p.

Research output: Contribution to journalReview article

14 Scopus citations
4 Scopus citations

Transmission pathways and mediators as the basis for clinical pharmacology of pain

Kirkpatrick, D. R., McEntire, D. M., Smith, T. A., Dueck, N. P., Kerfeld, M. J., Hambsch, Z. J., Nelson, T. J., Reisbig, M. & Agrawal, D. K., Oct 2 2016, In : Expert Review of Clinical Pharmacology. 9, 10, p. 1363-1387 25 p.

Research output: Contribution to journalReview article

3 Scopus citations

Triggering receptor expressed on myeloid cells and 5’adenosine monophosphate-activated protein kinase in the inflammatory response: a potential therapeutic target

Thankam, F. G., Dilisio, M., Dougherty, K. A., Dietz, N. E. & Agrawal, D. K., Nov 1 2016, In : Expert Review of Clinical Immunology. 12, 11, p. 1239-1249 11 p.

Research output: Contribution to journalReview article

11 Scopus citations

Vitamin D in atopic dermatitis, chronic urticaria and allergic contact dermatitis

Quirk, S. K., Rainwater, E., Shure, A. K. & Agrawal, D. K., Aug 2 2016, In : Expert Review of Clinical Immunology. 12, 8, p. 839-847 9 p.

Research output: Contribution to journalReview article

9 Scopus citations