Department of Medical Microbiology and Immunology

Research Output 1978 2017

2017
3 Citations

A long noncoding RNA, lincRNA-Tnfaip3, acts as a coregulator of NF-κB to modulate inflammatory gene transcription in mouse macrophages

Ma, S., Ming, Z., Gong, A. Y., Wang, Y., Chen, X., Hu, G., Zhou, R., Shibata, A., Swanson, P. C. & Chen, X. M. Mar 1 2017 In : FASEB Journal. 31, 3, p. 1215-1225 11 p.

Research output: Research - peer-reviewArticle

Long Noncoding RNA
Macrophages
Transcription
Tumor Necrosis Factor-alpha
Genes
1 Citations

An enhanced emtricitabine-loaded long-acting nanoformulation for prevention or treatment of HIV infection

Mandal, S., Belshan, M., Holec, A., Zhou, Y. & Destache, C. J. Jan 1 2017 In : Antimicrobial Agents and Chemotherapy. 61, 1, e01475-16

Research output: Research - peer-reviewArticle

HIV Infections
Blood Cells
Emtricitabine
Nucleosides
Inhibitory Concentration 50

Continued expansion of USA300-like methicillin-resistant Staphylococcus aureus (MRSA) among hospitalized patients in the United States

Tickler, I. A., Goering, R. V., Mediavilla, J. R., Kreiswirth, B. N. & Tenover, F. C. Feb 1 2017 (Accepted/In press) In : Diagnostic Microbiology and Infectious Disease.

Research output: Research - peer-reviewArticle

Methicillin-Resistant Staphylococcus aureus
Blood Culture
Mupirocin
Levofloxacin
Clindamycin
1 Citations
Cryptosporidium parvum
Epigenomics
Parasites
Epithelial Cells
RNA

Lineage II (Serovar 1/2a and 1/2c) Human Listeria monocytogenes Pulsed-Field Gel Electrophoresis Types Divided into PFGE Groups Using the Band Patterns below 145.5 kb

Lopez-Valladares, G., Danielsson-Tham, M. L., Goering, R. V. & Tham, W. Jan 1 2017 In : Foodborne Pathogens and Disease. 14, 1, p. 8-16 9 p.

Research output: Research - peer-reviewArticle

pulsed-field gel electrophoresis
Listeria monocytogenes
serotypes
Pulsed Field Gel Electrophoresis
Serogroup
2 Citations

Long non-coding RNAs (lncRNAs) and their transcriptional control of inflammatory responses

Mathy, N. W. & Chen, X. M. 2017 In : Journal of Biological Chemistry. 292, 30, p. 12375-12382 8 p.

Research output: Research - peer-reviewShort survey

Long Noncoding RNA
Transcription
Genes
RNA-Binding Proteins
Scaffolds

Ploidy variation in fungi: Polyploidy, aneuploidy, and genome evolution

Todd, R. T., Forche, A. & Selmecki, A. Jul 1 2017 In : Microbiology Spectrum. 5, 4, FUNK-0051-2016

Research output: Research - peer-reviewArticle

Genome Size
Aptitude
Polyploidy
Ploidies
Aneuploidy
1 Citations

Prion replication without host adaptation during interspecies transmissions

Bian, J., Khaychuk, V., Angers, R. C., Fernández-Borges, N., Vidal, E., Meyerett-Reid, C., Kim, S., Calvi, C. L., Bartz, J. C., Hoover, E. A., Agrimi, U., Richt, J. A., Castilla, J. & Telling, G. C. Jan 31 2017 In : Proceedings of the National Academy of Sciences of the United States of America. 114, 5, p. 1141-1146 6 p.

Research output: Research - peer-reviewArticle

Prions
Horses
Deer
Mink
Prion Diseases

PrPScformation and clearance as determinants of prion tropism

Shikiya, R. A., Langenfeld, K. A., Eckland, T. E., Trinh, J., Holec, S. A. M., Mathiason, C. K., Kincaid, A. E. & Bartz, J. C. Mar 1 2017 In : PLoS Pathogens. 13, 3, e1006298

Research output: Research - peer-reviewArticle

Mink
Tropism
Prions
Brain Diseases
Infection
2016
1 Citations

Absence of caveolin-1 leads to delayed development of chronic lymphocytic leukemia in Eμ-TCL1 mouse model

Shukla, A., Cutucache, C. E., Sutton, G. L., Pitner, M. A., Rai, K., Rai, S., Opavsky, R., Swanson, P. C. & Joshi, S. S. Jan 1 2016 In : Experimental Hematology. 44, 1, p. 30-37.e1

Research output: Research - peer-reviewArticle

Caveolin 1
B-Cell Chronic Lymphocytic Leukemia
Lymph Nodes
Bone Marrow
Gene Expression Profiling

A multiplex real-time PCR assay for identification of multi-drug resistant Gram-negative pathogens

Torres, M. P., Porter, L. R., Morrow, S., Connelly, C. M. & Hanson, N. D. Oct 1 2016 In : BioTechniques. 61, 4, p. 212-213 2 p.

Research output: Research - peer-reviewComment/debate

2 Citations

Beyond muscles: The untapped potential of creatine

Riesberg, L. A., Weed, S. A., McDonald, T. L., Eckerson, J. M. & Drescher, K. M. Aug 1 2016 In : International Immunopharmacology. 37, p. 31-42 12 p.

Research output: Research - peer-reviewArticle

Creatine
Muscles
Immune System
Sarcopenia
Wasting Syndrome
1 Citations

Characterization of methicillin-resistant Staphylococcus aureus isolated at Tripoli Medical Center, Libya, between 2008 and 2014

BenDarif, E., Khalil, A., Rayes, A., Bennour, E., Dhawi, A., Lowe, J. J., Gibbs, S. & Goering, R. V. Dec 1 2016 In : Journal of Medical Microbiology. 65, 12, p. 1472-1475 4 p., 000384

Research output: Research - peer-reviewArticle

Libya
Methicillin-Resistant Staphylococcus aureus
Population
Fluoroquinolones
Infection Control
2 Citations

Cyclophilin B enhances HIV-1 infection

DeBoer, J., Madson, C. J. & Belshan, M. Feb 1 2016 In : Virology. 489, p. 282-291 10 p.

Research output: Research - peer-reviewArticle

HIV Infections
HIV-1
cyclophilin B
Nuclear Localization Signals
Cell Nucleus Active Transport
1 Citations

Evaluation of CTX-M steady-state mRNA, mRNA half-life and protein production in various STs of Escherichia coli

Geyer, C. N., Fowler, R. C., Johnson, J. R., Johnston, B., Weissman, S. J., Hawkey, P. & Hanson, N. D. Mar 1 2016 In : Journal of Antimicrobial Chemotherapy. 71, 3, p. 607-616 10 p., dkv388

Research output: Research - peer-reviewArticle

Half-Life
Escherichia coli
Messenger RNA
Proteins
galantide

From Slow Viruses to Prions

Bartz, J. C. Jul 1 2016 In : PLoS Pathogens. 12, 7, e1005543

Research output: Research - peer-reviewEditorial

1 Citations

IMP-27, a unique metallo-β-lactamase identified in geographically distinct isolates of Proteus mirabilis

Dixon, N., Fowler, R. C., Yoshizumi, A., Horiyama, T., Ishii, Y., Harrison, L., Geyer, C. N., Moland, E. S., Thomson, K. & Hanson, N. D. Oct 1 2016 In : Antimicrobial Agents and Chemotherapy. 60, 10, p. 6418-6421 4 p.

Research output: Research - peer-reviewArticle

Inosine Monophosphate
Proteus mirabilis
beta-Lactamases
Ceftazidime
Genes
4 Citations

Incongruity between prion conversion and incubation period following coinfection

Langenfeld, K. A., Shikiya, R. A., Kincaid, A. E. & Bartz, J. C. Jun 1 2016 In : Journal of Virology. 90, 12, p. 5715-5723 9 p.

Research output: Research - peer-reviewArticle

Mink
Prions
Brain Diseases
Coinfection
prions
4 Citations

Investigation of the HIV-1 matrix interactome during virus replication

Li, Y., Frederick, K. M., Haverland, N. A., Ciborowski, P. & Belshan, M. Feb 1 2016 In : Proteomics - Clinical Applications. 10, 2, p. 156-163 8 p.

Research output: Research - peer-reviewArticle

Virus Replication
HIV-1
Proteins
Viruses
Y-Box-Binding Protein 1
14 Citations

LincRNA-Cox2 modulates TNF-α-induced transcription of Il12b gene in intestinal epithelial cells through regulation of Mi-2/NuRD-mediated epigenetic histone modifications

Tong, Q., Gong, A. Y., Zhang, X. T., Lin, C., Ma, S., Chen, J., Hu, G. & Chen, X. M. Mar 1 2016 In : FASEB Journal. 30, 3, p. 1187-1197 11 p.

Research output: Research - peer-reviewArticle

Long Noncoding RNA
Nucleosomes
Transcription
Histones
Tumor Necrosis Factor-alpha
15 Citations

LincRNA-Cox2 promotes late inflammatory gene transcription in macrophages through modulating SWI/SNF-mediated chromatin remodeling

Hu, G., Gong, A. Y., Wang, Y., Ma, S., Chen, X., Chen, J., Su, C. J., Shibata, A., Strauss-Soukup, J. K., Drescher, K. M. & Chen, X. M. Mar 15 2016 In : Journal of Immunology. 196, 6, p. 2799-2808 10 p.

Research output: Research - peer-reviewArticle

Genetic Transcription
Long Noncoding RNA
Chromatin Assembly and Disassembly
Sucrose
Macrophages
2 Citations

NF45 and NF90 bind HIV-1 RNA and modulate HIV gene expression

Li, Y. & Belshan, M. Feb 16 2016 In : Viruses. 8, 2, 23

Research output: Research - peer-reviewArticle

Nuclear Factor 90 Proteins
HIV-1
HIV
RNA
Gene Expression

Plasmid-mediated β-lactamases: Nomadic microbial assassins lurking in multidrug resistant gram-negative strains

Connelly, C. M., Torres, M. P., Lechner, J., Porter, L. R., Morrow, S. & Hanson, N. D. Nov 1 2016 In : BioTechniques. 61, 5, p. 272-275 4 p.

Research output: Research - peer-reviewArticle

3 Citations

Prion strain diversity

Bartz, J. C. 2016 In : Cold Spring Harbor perspectives in medicine. 6, 12, a024349

Research output: Research - peer-reviewArticle

Prions
Prion Diseases
Phenotype
Animal Diseases
Tropism
5 Citations

Promoter Hypomethylation and Expression Is Conserved in Mouse Chronic Lymphocytic Leukemia Induced by Decreased or Inactivated Dnmt3a

Haney, S. L., Upchurch, G. M., Opavska, J., Klinkebiel, D., Hlady, R. A., Suresh, A., Pirruccello, S. J., Shukla, V., Lu, R., Costinean, S., Rizzino, A., Karpf, A. R., Joshi, S., Swanson, P. & Opavsky, R. May 10 2016 In : Cell Reports. 15, 6, p. 1190-1201 12 p.

Research output: Research - peer-reviewArticle

B-Cell Chronic Lymphocytic Leukemia
Genes
Loss of Heterozygosity
Methylation
Cytosine
1 Citations
nasal cavity
prions
hamsters
brain
mice

Structural and mutagenic analysis of metallo-β-lactamase IMP-18

Furuyama, T., Nonomura, H., Ishii, Y., Hanson, N. D. & Shimizu-Ibuka, A. Sep 1 2016 In : Antimicrobial Agents and Chemotherapy. 60, 9, p. 5521-5526 6 p.

Research output: Research - peer-reviewArticle

Inosine Monophosphate
beta-Lactamases
meropenem
Carbapenems
beta-Lactams
3 Citations

The nucleotide excision repair pathway protects Borrelia burgdorferi from nitrosative stress in Ixodes scapularis ticks

Bourret, T. J., Lawrence, K. A., Shaw, J. A., Lin, T., Norris, S. J. & Gherardini, F. C. Sep 7 2016 In : Frontiers in Microbiology. 7, SEP, 1397

Research output: Research - peer-reviewArticle

Ixodes
Borrelia burgdorferi
Ticks
DNA Repair
Reactive Nitrogen Species
11 Citations

Wide geographical dissemination of the multiresistant Staphylococcus capitis NRCS-A clone in neonatal intensive-care units

Butin, M., Rasigade, J. P., Martins-Simões, P., Meugnier, H., Lemriss, H., Goering, R. V., Kearns, A., Deighton, M. A., Denis, O., Ibrahimi, A., Claris, O., Vandenesch, F., Picaud, J. C. & Laurent, F. Jan 1 2016 In : Clinical Microbiology and Infection. 22, 1, p. 46-52 7 p.

Research output: Research - peer-reviewArticle

Neonatal Intensive Care Units
Staphylococcus
Clone Cells
Newborn Infant
Methicillin Resistance
2015
131 Citations

A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium

Checkley, W. , White, A. C. , Jaganath, D. , Arrowood, M. J. , Chalmers, R. M. , Chen, X. M. , Fayer, R. , Griffiths, J. K. , Guerrant, R. L. , Hedstrom, L. , Huston, C. D. , Kotloff, K. L. , Kang, G. , Mead, J. R. , Miller, M. , Petri, W. A. , Priest, J. W. , Roos, D. S. , Striepen, B. , Thompson, R. C. A. & 5 others Ward, H. D., Van Voorhis, W. A., Xiao, L., Zhu, G. & Houpt, E. R. Jan 1 2015 In : The Lancet Infectious Diseases. 15, 1, p. 85-94 10 p.

Research output: Research - peer-reviewReview article

Cryptosporidium
Vaccines
Therapeutics
Antigens
Cryptosporidiosis

Cd1d regulates B cell development but not B cell accumulation and IL10 production in mice with pathologic CD5+ B cell expansion

Palmer, V. L., Nganga, V. K., Rothermund, M. E., Perry, G. A. & Swanson, P. C. Nov 4 2015 In : BMC Immunology. 16, 1, 66

Research output: Research - peer-reviewArticle

Interleukin-10
B-Lymphocytes
B-Cell Chronic Lymphocytic Leukemia
Natural Killer T-Cells
T-Lymphocytes
8 Citations

Direct repeat unit (dru) typing of methicillin-resistant staphylococcus pseudintermedius from dogs and cats

Kadlec, K., Schwarz, S., Goering, R. V. & Weese, J. S. Dec 1 2015 In : Journal of Clinical Microbiology. 53, 12, p. 3760-3765 6 p.

Research output: Research - peer-reviewArticle

Methicillin Resistance
Nucleic Acid Repetitive Sequences
Staphylococcus
Cats
Dogs
2 Citations

Division of human listeria monocytogenes Pulsed-Field Gel Electrophoresis (PFGE) types belonging to Lineage I (Serovar 4b, 1/2b, and 3b) into PFGE groups

Lopez-Valladares, G., Danielsson-Tham, M. L., Goering, R. V. & Tham, W. May 1 2015 In : Foodborne Pathogens and Disease. 12, 5, p. 447-453 7 p.

Research output: Research - peer-reviewArticle

Pulsed Field Gel Electrophoresis
Listeria monocytogenes
Serogroup
pulsed-field gel electrophoresis
serotypes
7 Citations

Enteroviruses, hygiene and type 1 diabetes: Toward a preventive vaccine

Drescher, K. M., von Herrath, M. & Tracy, S. Jan 1 2015 In : Reviews in Medical Virology. 25, 1, p. 19-32 14 p.

Research output: Research - peer-reviewReview article

Enterovirus
Hygiene
Type 1 Diabetes Mellitus
Vaccines
Viruses
24 Citations

Identification of gram-negative bacteria and genetic resistance determinants from positive blood culture broths by use of the verigene gram-negative blood culture multiplex microarray-based molecular assay

Ledeboer, N. A., Lopansri, B. K., Dhiman, N., Cavagnolo, R., Carroll, K. C., Granato, P., Thomson, R., Butler-Wu, S. M., Berger, H., Samuel, L., Pancholi, P., Swyers, L., Hansen, G. T., Tran, N. K., Polage, C. R., Thomson, K. S., Hanson, N. D., Winegar, R. & Buchan, B. W. Aug 1 2015 In : Journal of Clinical Microbiology. 53, 8, p. 2460-2472 13 p.

Research output: Research - peer-reviewArticle

Gram-Negative Bacteria
Blood Culture
Klebsiella pneumoniae
Infection
Klebsiella oxytoca
12 Citations

Immediate and ongoing detection of prions in the blood of hamsters and deer following oral, nasal, or blood inoculations

Elder, A. M., Henderson, D. M., Nalls, A. V., Hoover, E. A., Kincaid, A. E., Bartz, J. C. & Mathiason, C. K. 2015 In : Journal of Virology. 89, 14, p. 7421-7424 4 p.

Research output: Research - peer-reviewArticle

prions
hamsters
deer
mouth
blood
8 Citations

Investigation of bovine serum albumin (BSA) attachment onto self-assembled monolayers (SAMs) using combinatorial quartz crystal microbalance with dissipation (QCM-D) and spectroscopic ellipsometry (SE)

Phan, H. T. M., Bartelt-Hunt, S., Rodenhausen, K. B., Schubert, M. & Bartz, J. C. Oct 27 2015 In : PLoS One. 10, 10, 0141282

Research output: Research - peer-reviewArticle

Spectroscopic ellipsometry
Quartz crystal microbalances
Self assembled monolayers
Bovine Serum Albumin
quartz
24 Citations

Microbial typing by matrix-assisted laser desorption ionization-time of flight mass spectrometry: Do we need guidance for data interpretation?

Spinali, S., Van Belkum, A., Goering, R. V., Girard, V., Welker, M., Van Nuenen, M., Pincus, D. H., Arsac, M. & Durand, G. Mar 1 2015 In : Journal of Clinical Microbiology. 53, 3, p. 760-765 6 p.

Research output: Research - peer-reviewReview article

Mass Spectrometry
Lasers
Pulsed Field Gel Electrophoresis
Microbiology
Fungi
2 Citations
2 Citations

Mitigation of Prion Infectivity and Conversion Capacity by a Simulated Natural Process—Repeated Cycles of Drying and Wetting

Yuan, Q., Eckland, T., Telling, G., Bartz, J. & Bartelt-Hunt, S. 2015 In : PLoS Pathogens. 11, 2, e1004638

Research output: Research - peer-reviewArticle

Prions
Soil
Chronic Wasting Disease
Scrapie
Goats
26 Citations

Nanoformulations of Rilpivirine for Topical Pericoital and Systemic Coitus-Independent Administration Efficiently Prevent HIV Transmission

Kovarova, M., Council, O. D., Date, A. A., Long, J. M., Nochii, T., Belshan, M., Shibata, A., Vincent, H., Baker, C. E., Thayer, W. O., Kraus, G., Lachaud-Durand, S., Williams, P., Destache, C. J. & Garcia, J. V. Aug 1 2015 In : PLoS Pathogens. 11, 8, e1005075

Research output: Research - peer-reviewArticle

Rilpivirine
Coitus
HIV
Pharmaceutical Preparations
Infection
3 Citations

Nasal associated lymphoid tissue of the Syrian golden hamster expresses high levels of PrPC

Clouse, M. D., Shikiya, R. A., Bartz, J. C. & Kincaid, A. E. Feb 2 2015 In : PLoS One. 10, 2, e0117935

Research output: Research - peer-reviewArticle

Mesocricetus
Lymphoid Tissue
Nose
tissues
Mesocricetus auratus
81 Citations

Polyploidy can drive rapid adaptation in yeast

Selmecki, A. M., Maruvka, Y. E., Richmond, P. A., Guillet, M., Shoresh, N., Sorenson, A. L., De, S., Kishony, R., Michor, F., Dowell, R. & Pellman, D. Mar 19 2015 In : Nature. 519, 7543, p. 349-351 3 p.

Research output: Research - peer-reviewArticle

Polyploidy
Yeasts
Genome
Mutation
Tetraploidy
3 Citations

ST2249-MRSA-III: A second major recombinant methicillin-resistant Staphylococcus aureus clone causing healthcare infection in the 1970s

Nimmo, G. R., Steen, J. A., Monecke, S., Ehricht, R., Slickers, P., Thomas, J. C., Appleton, S., Goering, R. V., Robinson, D. A. & Coombs, G. W. May 1 2015 In : Clinical Microbiology and Infection. 21, 5, p. 444-450 7 p.

Research output: Research - peer-reviewArticle

Methicillin-Resistant Staphylococcus aureus
Clone Cells
Delivery of Health Care
Infection
Genome
1 Citations
Porins
Cystic Fibrosis
Nitrates
Pseudomonas aeruginosa
Oxygen
9 Citations

Thermosensitive gel containing cellulose acetate phthalate-efavirenz combination nanoparticles for prevention of HIV-1 infection

Date, A. A., Shibata, A., McMullen, E., La Bruzzo, K., Bruck, P., Belshan, M., Zhou, Y. & Destache, C. J. Mar 1 2015 In : Journal of Biomedical Nanotechnology. 11, 3, p. 416-427 12 p.

Research output: Research - peer-reviewArticle

efavirenz
Nanoparticles
HIV Infections
HIV-1
Gels
2 Citations

Upregulation of KSRP by miR-27b provides IFNγ-induced post-transcriptional regulation of CX3CL1 in liver epithelial cells

Xia, Z., Lu, Y., Li, X., Mao, T., Chen, X. M. & Zhou, R. Dec 3 2015 In : Scientific Reports. 5, 17590

Research output: Research - peer-reviewArticle

Protein Splicing
Up-Regulation
Epithelial Cells
Liver
Messenger RNA

VprBP is required for efficient editing and selection of Igκ+ B cells, but is dispensable for Igλ+ and marginal zone B cell maturation and selection

Palmer, V. L., Aziz-Seible, R., Kassmeier, M. D., Rothermund, M., Perry, G. A. & Swanson, P. C. Aug 15 2015 In : Journal of Immunology. 195, 4, p. 1524-1537 14 p.

Research output: Research - peer-reviewArticle

B-Lymphocytes
Transgenic Mice
B-Lymphoid Precursor Cells
Ubiquitin-Protein Ligases
Transgenes
2014
59 Citations

Bacterial whole-genome sequencing revisited: Portable, scalable, and standardized analysis for typing and detection of virulence and antibiotic resistance genes

Leopold, S. R., Goering, R. V., Witten, A., Harmsen, D. & Mellmann, A. 2014 In : Journal of Clinical Microbiology. 52, 7, p. 2365-2370 6 p.

Research output: Research - peer-reviewArticle

Bacterial Genomes
Microbial Drug Resistance
Virulence
Genes
Methicillin-Resistant Staphylococcus aureus