Department of Medical Microbiology and Immunology

Research Output 1978 2017

2017
1 Citations

A long noncoding RNA, lincRNA-Tnfaip3, acts as a coregulator of NF-κB to modulate inflammatory gene transcription in mouse macrophages

Ma, S., Ming, Z., Gong, A. Y., Wang, Y., Chen, X., Hu, G., Zhou, R., Shibata, A., Swanson, P. C. & Chen, X. M. Mar 1 2017 In : FASEB Journal. 31, 3, p. 1215-1225 11 p.

Research output: Contribution to journalArticle

Long Noncoding RNA
Tumor Necrosis Factor-alpha
Macrophages
Genes
Proteins

An enhanced emtricitabine-loaded long-acting nanoformulation for prevention or treatment of HIV infection

Mandal, S., Belshan, M., Holec, A., Zhou, Y. & Destache, C. J. Jan 1 2017 In : Antimicrobial Agents and Chemotherapy. 61, 1, e01475-16

Research output: Contribution to journalArticle

HIV Infections
Blood Cells
Nucleosides
Inhibitory Concentration 50
HIV-1

Continued expansion of USA300-like methicillin-resistant Staphylococcus aureus (MRSA) among hospitalized patients in the United States

Tickler, I. A., Goering, R. V., Mediavilla, J. R., Kreiswirth, B. N. & Tenover, F. C. Feb 1 2017 In : Diagnostic Microbiology and Infectious Disease.

Research output: Contribution to journalArticle

Methicillin-Resistant Staphylococcus aureus
Mupirocin
Levofloxacin
Clindamycin
Multiple Drug Resistance
Cryptosporidium parvum
Epigenomics
Parasites
Epithelial Cells
RNA

Lineage II (Serovar 1/2a and 1/2c) Human Listeria monocytogenes Pulsed-Field Gel Electrophoresis Types Divided into PFGE Groups Using the Band Patterns below 145.5 kb

Lopez-Valladares, G., Danielsson-Tham, M. L., Goering, R. V. & Tham, W. Jan 1 2017 In : Foodborne Pathogens and Disease. 14, 1, p. 8-16 9 p.

Research output: Contribution to journalArticle

Pulsed Field Gel Electrophoresis
Listeria monocytogenes
Serogroup
pulsed-field gel electrophoresis
serotypes

Long non-coding RNAs (lncRNAs) and their transcriptional control of inflammatory responses

Mathy, N. W. & Chen, X. M. 2017 In : Journal of Biological Chemistry. 292, 30, p. 12375-12382 8 p.

Research output: Contribution to journalShort survey

Long Noncoding RNA
Blood Flow Velocity
Genes
Cyclic AMP Receptor Protein
Transcription

Ploidy variation in fungi: Polyploidy, aneuploidy, and genome evolution

Todd, R. T., Forche, A. & Selmecki, A. Jul 1 2017 In : Microbiology Spectrum. 5, 4, FUNK-0051-2016

Research output: Contribution to journalArticle

Genome Size
Polyploidy
Ploidies
Aneuploidy
Fungi
1 Citations

Prion replication without host adaptation during interspecies transmissions

Bian, J., Khaychuk, V., Angers, R. C., Fernández-Borges, N., Vidal, E., Meyerett-Reid, C., Kim, S., Calvi, C. L., Bartz, J. C., Hoover, E. A., Agrimi, U., Richt, J. A., Castilla, J. & Telling, G. C. Jan 31 2017 In : Proceedings of the National Academy of Sciences of the United States of America. 114, 5, p. 1141-1146 6 p.

Research output: Contribution to journalArticle

Prions
Horses
Deer

PrPScformation and clearance as determinants of prion tropism

Shikiya, R. A., Langenfeld, K. A., Eckland, T. E., Trinh, J., Holec, S. A. M., Mathiason, C. K., Kincaid, A. E. & Bartz, J. C. Mar 1 2017 In : PLoS Pathogens. 13, 3, e1006298

Research output: Contribution to journalArticle

Mink
Prions
Infection
Spleen
Lymphatic Vessels
2016
1 Citations

Absence of caveolin-1 leads to delayed development of chronic lymphocytic leukemia in Eμ-TCL1 mouse model

Shukla, A., Cutucache, C. E., Sutton, G. L., Pitner, M. A., Rai, K., Rai, S., Opavsky, R., Swanson, P. C. & Joshi, S. S. Jan 1 2016 In : Experimental Hematology. 44, 1, p. 30-37.e1

Research output: Contribution to journalArticle

Caveolin 1
B-Cell Chronic Lymphocytic Leukemia
Lymph Nodes
Bone Marrow
Gene Expression Profiling

A multiplex real-time PCR assay for identification of multi-drug resistant Gram-negative pathogens

Torres, M. P., Porter, L. R., Morrow, S., Connelly, C. M. & Hanson, N. D. Oct 1 2016 In : BioTechniques. 61, 4, p. 212-213 2 p.

Research output: Contribution to journalComment/debate

Multiplex Polymerase Chain Reaction
Real-Time Polymerase Chain Reaction
2 Citations

Beyond muscles: The untapped potential of creatine

Riesberg, L. A., Weed, S. A., McDonald, T. L., Eckerson, J. M. & Drescher, K. M. Aug 1 2016 In : International Immunopharmacology. 37, p. 31-42 12 p.

Research output: Contribution to journalArticle

Creatine
Muscles
Immune System
Sarcopenia
Wasting Syndrome
1 Citations

Characterization of methicillin-resistant Staphylococcus aureus isolated at Tripoli Medical Center, Libya, between 2008 and 2014

BenDarif, E., Khalil, A., Rayes, A., Bennour, E., Dhawi, A., Lowe, J. J., Gibbs, S. & Goering, R. V. Dec 1 2016 In : Journal of Medical Microbiology. 65, 12, p. 1472-1475 4 p., 000384

Research output: Contribution to journalArticle

Libya
Methicillin-Resistant Staphylococcus aureus
Fluoroquinolones
Infection Control
Communicable Diseases
1 Citations

Cyclophilin B enhances HIV-1 infection

DeBoer, J., Madson, C. J. & Belshan, M. Feb 1 2016 In : Virology. 489, p. 282-291 10 p.

Research output: Contribution to journalArticle

Cyclophilins
HIV Infections
HIV-1
Nuclear Localization Signals
Cell Nucleus Active Transport
1 Citations

Evaluation of CTX-M steady-state mRNA, mRNA half-life and protein production in various STs of Escherichia coli

Geyer, C. N., Fowler, R. C., Johnson, J. R., Johnston, B., Weissman, S. J., Hawkey, P. & Hanson, N. D. Mar 1 2016 In : Journal of Antimicrobial Chemotherapy. 71, 3, p. 607-616 10 p., dkv388

Research output: Contribution to journalArticle

Half-Life
Escherichia coli
Messenger RNA
Proteins
Piperacillin

From Slow Viruses to Prions

Bartz, J. C. Jul 1 2016 In : PLoS Pathogens. 12, 7, e1005543

Research output: Contribution to journalEditorial

Prions
Viruses
1 Citations

IMP-27, a unique metallo-β-lactamase identified in geographically distinct isolates of Proteus mirabilis

Dixon, N., Fowler, R. C., Yoshizumi, A., Horiyama, T., Ishii, Y., Harrison, L., Geyer, C. N., Moland, E. S., Thomson, K. & Hanson, N. D. Oct 1 2016 In : Antimicrobial Agents and Chemotherapy. 60, 10, p. 6418-6421 4 p.

Research output: Contribution to journalArticle

Inosine Monophosphate
Proteus mirabilis
beta-Lactamases
Ceftazidime
Genes
3 Citations

Incongruity between prion conversion and incubation period following coinfection

Langenfeld, K. A., Shikiya, R. A., Kincaid, A. E. & Bartz, J. C. Jun 1 2016 In : Journal of Virology. 90, 12, p. 5715-5723 9 p.

Research output: Contribution to journalArticle

Mink
Prions
Coinfection
incubation period
transmissible mink encephalopathy
4 Citations

Investigation of the HIV-1 matrix interactome during virus replication

Li, Y., Frederick, K. M., Haverland, N. A., Ciborowski, P. & Belshan, M. Feb 1 2016 In : Proteomics - Clinical Applications. 10, 2, p. 156-163 8 p.

Research output: Contribution to journalArticle

Virus Replication
HIV-1
Proteins
Bulimia
Enzyme Reactivators
12 Citations

LincRNA-Cox2 modulates TNF-α-induced transcription of Il12b gene in intestinal epithelial cells through regulation of Mi-2/NuRD-mediated epigenetic histone modifications

Tong, Q., Gong, A. Y., Zhang, X. T., Lin, C., Ma, S., Chen, J., Hu, G. & Chen, X. M. Mar 1 2016 In : FASEB Journal. 30, 3, p. 1187-1197 11 p.

Research output: Contribution to journalArticle

Long Noncoding RNA
Nucleosomes
Epigenomics
Histones
Tumor Necrosis Factor-alpha
11 Citations

LincRNA-Cox2 promotes late inflammatory gene transcription in macrophages through modulating SWI/SNF-mediated chromatin remodeling

Hu, G., Gong, A. Y., Wang, Y., Ma, S., Chen, X., Chen, J., Su, C. J., Shibata, A., Strauss-Soukup, J. K., Drescher, K. M. & Chen, X. M. Mar 15 2016 In : Journal of Immunology. 196, 6, p. 2799-2808 10 p.

Research output: Contribution to journalArticle

Genetic Transcription
Long Noncoding RNA
Chromatin Assembly and Disassembly
Sucrose
Macrophages
2 Citations

NF45 and NF90 bind HIV-1 RNA and modulate HIV gene expression

Li, Y. & Belshan, M. Feb 16 2016 In : Viruses. 8, 2, 23

Research output: Contribution to journalArticle

Nuclear Factor 90 Proteins
HIV-1
HIV
RNA
Gene Expression

Plasmid-mediated β-lactamases: Nomadic microbial assassins lurking in multidrug resistant gram-negative strains

Connelly, C. M., Torres, M. P., Lechner, J., Porter, L. R., Morrow, S. & Hanson, N. D. Nov 1 2016 In : BioTechniques. 61, 5, p. 272-275 4 p.

Research output: Contribution to journalArticle

beta-Lactamases
Plasmids
1 Citations

Prion strain diversity

Bartz, J. C. 2016 In : Cold Spring Harbor perspectives in medicine. 6, 12, a024349

Research output: Contribution to journalArticle

Prions
Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing)
Supravalvular Aortic Stenosis
Prion Diseases
Phenotype
3 Citations

Promoter Hypomethylation and Expression Is Conserved in Mouse Chronic Lymphocytic Leukemia Induced by Decreased or Inactivated Dnmt3a

Haney, S. L., Upchurch, G. M., Opavska, J., Klinkebiel, D., Hlady, R. A., Suresh, A., Pirruccello, S. J., Shukla, V., Lu, R., Costinean, S., Rizzino, A., Karpf, A. R., Joshi, S., Swanson, P. & Opavsky, R. May 10 2016 In : Cell Reports. 15, 6, p. 1190-1201 12 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Supravalvular Aortic Stenosis
Methacholine Compounds
Cyclic AMP Receptor Protein
Loss of Heterozygosity
1 Citations
Prions
Nasal Cavity
Cricetinae
Brain
prions

Structural and mutagenic analysis of metallo-β-lactamase IMP-18

Furuyama, T., Nonomura, H., Ishii, Y., Hanson, N. D. & Shimizu-Ibuka, A. Sep 1 2016 In : Antimicrobial Agents and Chemotherapy. 60, 9, p. 5521-5526 6 p.

Research output: Contribution to journalArticle

Inosine Monophosphate
beta-Lactamases
Carbapenems
beta-Lactams
Pseudomonas aeruginosa
2 Citations

The nucleotide excision repair pathway protects Borrelia burgdorferi from nitrosative stress in Ixodes scapularis ticks

Bourret, T. J., Lawrence, K. A., Shaw, J. A., Lin, T., Norris, S. J. & Gherardini, F. C. Sep 7 2016 In : Frontiers in Microbiology. 7, SEP, 1397

Research output: Contribution to journalArticle

Ixodes
Borrelia burgdorferi
Ticks
DNA Repair
Reactive Nitrogen Species
8 Citations

Wide geographical dissemination of the multiresistant Staphylococcus capitis NRCS-A clone in neonatal intensive-care units

Butin, M., Rasigade, J. P., Martins-Simões, P., Meugnier, H., Lemriss, H., Goering, R. V., Kearns, A., Deighton, M. A., Denis, O., Ibrahimi, A., Claris, O., Vandenesch, F., Picaud, J. C. & Laurent, F. Jan 1 2016 In : Clinical Microbiology and Infection. 22, 1, p. 46-52 7 p.

Research output: Contribution to journalArticle

Neonatal Intensive Care Units
Staphylococcus
Clone Cells
Newborn Infant
Methicillin Resistance
2015
114 Citations

A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium

Checkley, W. , White, A. C. , Jaganath, D. , Arrowood, M. J. , Chalmers, R. M. , Chen, X. M. , Fayer, R. , Griffiths, J. K. , Guerrant, R. L. , Hedstrom, L. , Huston, C. D. , Kotloff, K. L. , Kang, G. , Mead, J. R. , Miller, M. , Petri, W. A. , Priest, J. W. , Roos, D. S. , Striepen, B. , Thompson, R. C. A. & 5 others Ward, H. D., Van Voorhis, W. A., Xiao, L., Zhu, G. & Houpt, E. R. Jan 1 2015 In : The Lancet Infectious Diseases. 15, 1, p. 85-94 10 p.

Research output: Contribution to journalReview article

Cryptosporidium
Vaccines
Antigens
Cryptosporidiosis
Immunocompromised Host

Cd1d regulates B cell development but not B cell accumulation and IL10 production in mice with pathologic CD5+ B cell expansion

Palmer, V. L., Nganga, V. K., Rothermund, M. E., Perry, G. A. & Swanson, P. C. Nov 4 2015 In : BMC Immunology. 16, 1, 66

Research output: Contribution to journalArticle

Interleukin-10
B-Lymphocytes
B-Cell Chronic Lymphocytic Leukemia
Natural Killer T-Cells
T-Lymphocytes
6 Citations

Direct repeat unit (dru) typing of methicillin-resistant staphylococcus pseudintermedius from dogs and cats

Kadlec, K., Schwarz, S., Goering, R. V. & Weese, J. S. Dec 1 2015 In : Journal of Clinical Microbiology. 53, 12, p. 3760-3765 6 p.

Research output: Contribution to journalArticle

Methicillin Resistance
Nucleic Acid Repetitive Sequences
Staphylococcus
Cats
Dogs
2 Citations

Division of human listeria monocytogenes Pulsed-Field Gel Electrophoresis (PFGE) types belonging to Lineage I (Serovar 4b, 1/2b, and 3b) into PFGE groups

Lopez-Valladares, G., Danielsson-Tham, M. L., Goering, R. V. & Tham, W. May 1 2015 In : Foodborne Pathogens and Disease. 12, 5, p. 447-453 7 p.

Research output: Contribution to journalArticle

Pulsed Field Gel Electrophoresis
Listeria monocytogenes
Serogroup
pulsed-field gel electrophoresis
Serotyping
7 Citations

Enteroviruses, hygiene and type 1 diabetes: Toward a preventive vaccine

Drescher, K. M., von Herrath, M. & Tracy, S. Jan 1 2015 In : Reviews in Medical Virology. 25, 1, p. 19-32 14 p.

Research output: Contribution to journalReview article

Enterovirus
Hygiene
Vaccines
Viruses
Poliomyelitis
21 Citations

Identification of gram-negative bacteria and genetic resistance determinants from positive blood culture broths by use of the verigene gram-negative blood culture multiplex microarray-based molecular assay

Ledeboer, N. A., Lopansri, B. K., Dhiman, N., Cavagnolo, R., Carroll, K. C., Granato, P., Thomson, R., Butler-Wu, S. M., Berger, H., Samuel, L., Pancholi, P., Swyers, L., Hansen, G. T., Tran, N. K., Polage, C. R., Thomson, K. S., Hanson, N. D., Winegar, R. & Buchan, B. W. Aug 1 2015 In : Journal of Clinical Microbiology. 53, 8, p. 2460-2472 13 p.

Research output: Contribution to journalArticle

Gram-Negative Bacteria
Klebsiella pneumoniae
Infection
Klebsiella oxytoca
Citrobacter
10 Citations

Immediate and ongoing detection of prions in the blood of hamsters and deer following oral, nasal, or blood inoculations

Elder, A. M., Henderson, D. M., Nalls, A. V., Hoover, E. A., Kincaid, A. E., Bartz, J. C. & Mathiason, C. K. 2015 In : Journal of Virology. 89, 14, p. 7421-7424 4 p.

Research output: Contribution to journalArticle

Deer
Prions
Nose
Cricetinae
blood
8 Citations

Investigation of bovine serum albumin (BSA) attachment onto self-assembled monolayers (SAMs) using combinatorial quartz crystal microbalance with dissipation (QCM-D) and spectroscopic ellipsometry (SE)

Phan, H. T. M., Bartelt-Hunt, S., Rodenhausen, K. B., Schubert, M. & Bartz, J. C. Oct 27 2015 In : PLoS One. 10, 10, 0141282

Research output: Contribution to journalArticle

Quartz Crystal Microbalance Techniques
Bovine Serum Albumin
bovine serum albumin
Edema Disease of Swine
Adsorption
22 Citations

Microbial typing by matrix-assisted laser desorption ionization-time of flight mass spectrometry: Do we need guidance for data interpretation?

Spinali, S., Van Belkum, A., Goering, R. V., Girard, V., Welker, M., Van Nuenen, M., Pincus, D. H., Arsac, M. & Durand, G. Mar 1 2015 In : Journal of Clinical Microbiology. 53, 3, p. 760-765 6 p.

Research output: Contribution to journalReview article

Mass Spectrometry
Lasers
Pulsed Field Gel Electrophoresis
Microbiology
Fungi
1 Citations
Tumor-Infiltrating Lymphocytes
Microsatellite Instability
Disease-Free Survival
Colorectal Neoplasms
2 Citations

Mitigation of Prion Infectivity and Conversion Capacity by a Simulated Natural Process—Repeated Cycles of Drying and Wetting

Yuan, Q., Eckland, T., Telling, G., Bartz, J. & Bartelt-Hunt, S. 2015 In : PLoS Pathogens. 11, 2, e1004638

Research output: Contribution to journalArticle

Prions
Soil
Chronic Wasting Disease
Scrapie
Goats
25 Citations

Nanoformulations of Rilpivirine for Topical Pericoital and Systemic Coitus-Independent Administration Efficiently Prevent HIV Transmission

Kovarova, M., Council, O. D., Date, A. A., Long, J. M., Nochii, T., Belshan, M., Shibata, A., Vincent, H., Baker, C. E., Thayer, W. O., Kraus, G., Lachaud-Durand, S., Williams, P., Destache, C. J. & Garcia, J. V. Aug 1 2015 In : PLoS Pathogens. 11, 8, e1005075

Research output: Contribution to journalArticle

Coitus
HIV
Infection
HIV-1
Nanoparticles
2 Citations

Nasal associated lymphoid tissue of the Syrian golden hamster expresses high levels of PrPC

Clouse, M. D., Shikiya, R. A., Bartz, J. C. & Kincaid, A. E. Feb 2 2015 In : PLoS One. 10, 2, e0117935

Research output: Contribution to journalArticle

Mesocricetus
Lymphoid Tissue
Nose
golden hamsters
Library Catalogs
65 Citations

Polyploidy can drive rapid adaptation in yeast

Selmecki, A. M., Maruvka, Y. E., Richmond, P. A., Guillet, M., Shoresh, N., Sorenson, A. L., De, S., Kishony, R., Michor, F., Dowell, R. & Pellman, D. Mar 19 2015 In : Nature. 519, 7543, p. 349-351 3 p.

Research output: Contribution to journalArticle

Polyploidy
Yeasts
Genome
Mutation
Tetraploidy
3 Citations

ST2249-MRSA-III: A second major recombinant methicillin-resistant Staphylococcus aureus clone causing healthcare infection in the 1970s

Nimmo, G. R., Steen, J. A., Monecke, S., Ehricht, R., Slickers, P., Thomas, J. C., Appleton, S., Goering, R. V., Robinson, D. A. & Coombs, G. W. May 1 2015 In : Clinical Microbiology and Infection. 21, 5, p. 444-450 7 p.

Research output: Contribution to journalArticle

Methicillin-Resistant Staphylococcus aureus
Clone Cells
Delivery of Health Care
Infection
Genome
1 Citations
Porins
Cystic Fibrosis
Nitrates
Pseudomonas aeruginosa
Oxygen
8 Citations

Thermosensitive gel containing cellulose acetate phthalate-efavirenz combination nanoparticles for prevention of HIV-1 infection

Date, A. A., Shibata, A., McMullen, E., La Bruzzo, K., Bruck, P., Belshan, M., Zhou, Y. & Destache, C. J. Mar 1 2015 In : Journal of Biomedical Nanotechnology. 11, 3, p. 416-427 12 p.

Research output: Contribution to journalArticle

Cellulose
Nanoparticles
HIV Infections
HIV-1
Acetates
1 Citations

Upregulation of KSRP by miR-27b provides IFNγ-induced post-transcriptional regulation of CX3CL1 in liver epithelial cells

Xia, Z., Lu, Y., Li, X., Mao, T., Chen, X. M. & Zhou, R. Dec 3 2015 In : Scientific Reports. 5, 17590

Research output: Contribution to journalArticle

Protein Splicing
Up-Regulation
Epithelial Cells
Liver
Messenger RNA

VprBP is required for efficient editing and selection of Igκ+ B cells, but is dispensable for Igλ+ and marginal zone B cell maturation and selection

Palmer, V. L., Aziz-Seible, R., Kassmeier, M. D., Rothermund, M., Perry, G. A. & Swanson, P. C. Aug 15 2015 In : Journal of Immunology. 195, 4, p. 1524-1537 14 p.

Research output: Contribution to journalArticle

B-Lymphocytes
Transgenic Mice
B-Lymphoid Precursor Cells
Ubiquitin-Protein Ligases
Transgenes
2014
Microbial Drug Resistance
56 Citations

Bacterial whole-genome sequencing revisited: Portable, scalable, and standardized analysis for typing and detection of virulence and antibiotic resistance genes

Leopold, S. R., Goering, R. V., Witten, A., Harmsen, D. & Mellmann, A. 2014 In : Journal of Clinical Microbiology. 52, 7, p. 2365-2370 6 p.

Research output: Contribution to journalArticle

Bacterial Genomes
Microbial Drug Resistance
Virulence
Genes
Methicillin-Resistant Staphylococcus aureus