Department of Medical Microbiology and Immunology

Research Output

2010

NFκB p50-CCAAT/enhancer-binding protein β (C/EBPβ)-mediated transcriptional repression of microRNA let-7i following microbial infection

O'Hara, S. P., Splinter, P. L., Gajdos, G. B., Trussoni, C. E., Fernandez-Zapico, M. E., Chen, X. M. & LaRusso, N. F., Jan 1 2010, In : Journal of Biological Chemistry. 285, 1, p. 216-225 10 p.

Research output: Contribution to journalArticle

81 Scopus citations

Outbreak of carbapenem-resistant Klebsiella pneumoniae in Puerto Rico associated with a novel carbapenemase variant

Gregory, C. J., Llata, E., Stine, N., Gould, C., Santiago, L. M., Vazquez, G. J., Robledo, I. E., Srinivasan, A., Goering, R. V. & Tomashek, K. M., May 1 2010, In : Infection Control and Hospital Epidemiology. 31, 5, p. 476-484 9 p.

Research output: Contribution to journalArticle

77 Scopus citations

Outbreak of skin infections in college football team members due to an unusual strain of community-acquired methicillin-susceptible Staphylococcus aureus

Fontanilla, J. M., Kirkland, K. B., Talbot, E. A., Powell, K. E., Schwartzman, J. D., Goering, R. V. & Parsonnet, J., Feb 1 2010, In : Journal of clinical microbiology. 48, 2, p. 609-611 3 p.

Research output: Contribution to journalArticle

17 Scopus citations

Positive extended-spectrum-β-lactamase (ESBL) screening results may be due to AmpC β-lactamases more often than to ESBLs

Munier, G. K., Johnson, C. L., Snyder, J. W., Moland, E. S., Hanson, N. D. & Thomson, K. S., Feb 1 2010, In : Journal of clinical microbiology. 48, 2, p. 673-674 2 p.

Research output: Contribution to journalLetter

29 Scopus citations
143 Scopus citations
2009

Abnormal brain iron homeostasis in human and animal prion disorders

Singh, A., Isaac, A. O., Luo, X., Mohan, M. L., Cohen, M. L., Chen, F., Kong, Q., Bartz, J. & Singh, N., Mar 2009, In : PLoS pathogens. 5, 3

Research output: Contribution to journalArticle

68 Scopus citations

Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance

Selmecki, A., Dulmage, K., Cowen, L. E., Anderson, J. B. & Berman, J., Oct 2009, In : PLoS Genetics. 5, 10, e1000705.

Research output: Contribution to journalArticle

168 Scopus citations

Aneuploid chromosomes are highly unstable during DNA transformation of candida albicans∇

Bouchonville, K., Forche, A., Tang, K. E. S., Selmecki, A. & Berman, J., Oct 2009, In : Eukaryotic Cell. 8, 10, p. 1554-1566 13 p.

Research output: Contribution to journalArticle

46 Scopus citations

Antibacterial-resistant Pseudomonas aeruginosa: Clinical impact and complex regulation of chromosomally encoded resistance mechanisms

Lister, P. D., Wolter, D. J. & Hanson, N. D., Oct 1 2009, In : Clinical Microbiology Reviews. 22, 4, p. 582-610 29 p.

Research output: Contribution to journalReview article

830 Scopus citations
44 Scopus citations

Classification of staphylococcal cassette chromosome mec (SCCmec): Guidelines for reporting novel SCCmec elements

Ito, T., Hiramatsu, K., Oliveira, D. C., De Lencastre, H., Zhang, K., Westh, H., O'Brien, F., Giffard, P. M., Coleman, D., Tenover, F. C., Boyle-Vavra, S., Skov, R. L., Enright, M. C., Kreiswirth, B., Kwan, S. K., Grundmann, H., Laurent, F., Sollid, J. E., Kearns, A. M., Goering, R. & 3 others, John, J. F., Daum, R. & Soderquist, B., Dec 1 2009, In : Antimicrobial agents and chemotherapy. 53, 12, p. 4961-4967 7 p.

Research output: Contribution to journalComment/debate

460 Scopus citations

Comparative genomic analysis of European and Middle Eastern community-associated methicillin-resistant Staphylococcus aureus (CC80:ST80-IV) isolates by high-density microarray

Goering, R. V., Larsen, A. R., Skov, R., Tenover, F. C., Anderson, K. L. & Dunman, P. M., Jan 1 2009, In : Clinical Microbiology and Infection. 15, 8, p. 748-755 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Early steps of V(D)J rearrangement: Insights from biochemical studies of RAG-RSS complexes

Swanson, P. C., Kumar, S. & Raval, P., Dec 1 2009, V(D)J Recombination. Ferrier, P. (ed.). p. 1-15 15 p. (Advances in Experimental Medicine and Biology; vol. 650).

Research output: Chapter in Book/Report/Conference proceedingChapter

13 Scopus citations

Evolution in Candida albicans populations during a single passage through a mouse host

Forche, A., Magee, P. T., Selmecki, A., Berman, J. & May, G., Jul 2009, In : Genetics. 182, 3, p. 799-811 13 p.

Research output: Contribution to journalArticle

84 Scopus citations
7 Scopus citations

Genetic commonality of macrolide-resistant group A beta hemolytic streptococcus pharyngeal strains

Myers, A. L., Jackson, M. A., Selvarangan, R., Goering, R. V. & Harrison, C., Dec 1 2009, In : Annals of Clinical Microbiology and Antimicrobials. 8, 33.

Research output: Contribution to journalArticle

2 Scopus citations

HIV-1 tat protein suppresses cholangiocyte toll- like receptor 4 expression and defense against cryptosporidium parvum

O'Hara, S. P., Small, A. J., Gajdos, G. B., Badley, A. D., Chen, X. M. & LaRusso, N. F., Apr 15 2009, In : Journal of Infectious Diseases. 199, 8, p. 1195-1204 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

HMGB1/2 can target DNA for illegitimate cleavage by the RAG1/2 complex

Zhang, M. & Swanson, P. C., Mar 24 2009, In : BMC Molecular Biology. 10, 24.

Research output: Contribution to journalArticle

7 Scopus citations

Influence of prion strain on prion protein adsorption to soil in a competitive matrix

Saunders, S. E., Bartz, J. C. & Bartelt-Hunt, S. L., Jul 15 2009, In : Environmental Science and Technology. 43, 14, p. 5242-5248 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

In vivo biotinylation and capture of HIV-1 matrix and integrase proteins

Belshan, M., Schweitzer, C. J., Donnellan, M. R., Lu, R. & Engelman, A., Aug 1 2009, In : Journal of Virological Methods. 159, 2, p. 178-184 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Lymphocyte recruitment into the tumor site is altered in patients with MSI-H colon cancer

Drescher, K. M., Sharma, P., Watson, P., Gatalica, Z., Thibodeau, S. N. & Lynch, H. T., Sep 1 2009, In : Familial cancer. 8, 3, p. 231-239 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Methicillin-resistant Staphylococcus aureus strain USA300: Origin and epidemiology

Tenover, F. C. & Goering, R. V., Aug 27 2009, In : Journal of Antimicrobial Chemotherapy. 64, 3, p. 441-446 6 p.

Research output: Contribution to journalReview article

282 Scopus citations

MicroRNA-513 regulates B7-H1 translation and is involved in IFN-γ-induced B7-H1 expression in cholangiocytes

Gong, A. Y., Zhou, R., Hu, G., Li, X., Splinter, P. L., O'Hara, S. P., LaRusso, N. F., Soukup, G. A., Dong, H. & Chen, X. M., Feb 1 2009, In : Journal of Immunology. 182, 3, p. 1325-1333 9 p.

Research output: Contribution to journalArticle

Open Access
134 Scopus citations

MicroRNA-98 and let-7 confer cholangiocyte expression of cytokine-inducible Src homology 2-containing protein in response to microbial challenge

Hu, G., Zhou, R., Liu, J., Gong, A. Y., Eischeid, A. N., Dittman, J. W. & Chen, X. M., Aug 1 2009, In : Journal of Immunology. 183, 3, p. 1617-1624 8 p.

Research output: Contribution to journalArticle

93 Scopus citations

MicroRNAs and epithelial immunity

Liu, J., Drescher, K. M. & Chen, X. M., Nov 9 2009, In : International Reviews of Immunology. 28, 3-4, p. 139-154 16 p.

Research output: Contribution to journalReview article

14 Scopus citations

MicroRNA signatures in liver diseases

Chen, X. M., Apr 14 2009, In : World Journal of Gastroenterology. 15, 14, p. 1665-1672 8 p.

Research output: Contribution to journalEditorial

97 Scopus citations

Molecular mechanisms of Cryptosporidium-induced host actin cytoskeleton dynamics

O'hara, S. P., Chen, X. M. & LaRusso, N. F., Feb 25 2009, Giardia and Cryptosporidium: From Molecules to Diseases. CABI Publishing, p. 418-427 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Molecular mechanism underlying RAG1/RAG2 synaptic complex formation

Shlyakhtenko, L. S., Gilmore, J., Kriatchko, A. N., Kumar, S., Swanson, P. C. & Lyubchenko, Y. L., Jul 31 2009, In : Journal of Biological Chemistry. 284, 31, p. 20956-20965 10 p.

Research output: Contribution to journalArticle

24 Scopus citations
165 Scopus citations
31 Scopus citations

Neocentromeres form efficiently at multiple possible loci in candida albicans

Ketel, C., Wang, H. S. W., McClellan, M., Bouchonville, K., Selmecki, A., Lahav, T., Gerami-Nejad, M. & Berman, J., Mar 2009, In : PLoS Genetics. 5, 3

Research output: Contribution to journalArticle

108 Scopus citations

NF-kappaB p65-dependent transactivation of miRNA genes following Cryptosporidium parvum infection stimulates epithelial cell immune responses

Zhou, R., Hu, G., Liu, J., Gong, A. Y., Drescher, K. M. & Chen, X. M., Dec 2009, In : PLoS pathogens. 5, 12, e1000681.

Research output: Contribution to journalArticle

146 Scopus citations

Phenotypic and enzymatic comparative analysis of the novel KPC variant KPC-5 and its evolutionary variants, KPC-2 and KPC-4

Wolter, D. J., Kurpiel, P. M., Woodford, N., Palepou, M. F. I., Goering, R. V. & Hanson, N. D., Feb 1 2009, In : Antimicrobial agents and chemotherapy. 53, 2, p. 557-562 6 p.

Research output: Contribution to journalArticle

82 Scopus citations

Prion protein adsorption to soil in a competitive matrix is slow and reduced

Saunders, S. E., Bartz, J. C. & Bartelt-Hunt, S. L., Oct 15 2009, In : Environmental Science and Technology. 43, 20, p. 7728-7733 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Prion strain targeting independent of strain-specific neuronal tropism

Ayers, J. I., Kincaid, A. E. & Bartz, J. C., Jan 1 2009, In : Journal of Virology. 83, 1, p. 81-87 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

Rapid, high-throughput detection of PrPSc by 96-well immunoassay

Kramer, M. L. & Bartz, J. C., Jan 1 2009, In : Prion. 3, 1, p. 44-48 5 p.

Research output: Contribution to journalArticle

11 Scopus citations

Surveillance of carbapenem-resistant pseudomonas aeruginosa isolates from Puerto Rican Medical Center Hospitals: Dissemination of KPC and IMP-18 β-lactamases

Wolter, D. J., Khalaf, N., Robledo, I. E., Vázquez, J. G., Santé, I. M., Aquino, E. E., Goering, R. V. & Hanson, N. D., Apr 1 2009, In : Antimicrobial agents and chemotherapy. 53, 4, p. 1660-1664 5 p.

Research output: Contribution to journalArticle

64 Scopus citations

Two distinct clones of methicillin-resistant Staphylococcus aureus (MRSA) with the same USA300 pulsed-field gel electrophoresis profile: A potential pitfall for identification of USA300 community-associated MRSA

Larsen, A. R., Goering, R., Stegger, M., Lindsay, J. A., Gould, K. A., Hinds, J., Sørum, M., Westh, H., Boye, K. & Skov, R., Nov 1 2009, In : Journal of clinical microbiology. 47, 11, p. 3765-3768 4 p.

Research output: Contribution to journalArticle

40 Scopus citations
2008

5′ terminal deletions in the genome of a coxsackievirus B2 strain occurred naturally in human heart

Chapman, N. M., Kim, K. S., Drescher, K. M., Oka, K. & Tracy, S., Jun 5 2008, In : Virology. 375, 2, p. 480-491 12 p.

Research output: Contribution to journalArticle

56 Scopus citations

A Biochemically Defined System for Coding Joint Formation in V(D)J Recombination

Lu, H., Shimazaki, N., Raval, P., Gu, J., Watanabe, G., Schwarz, K., Swanson, P. C. & Lieber, M. R., Aug 22 2008, In : Molecular Cell. 31, 4, p. 485-497 13 p.

Research output: Contribution to journalArticle

24 Scopus citations

An isochromosome confers drug resistance in vivo by amplification of two genes, ERG11 and TAC1

Selmecki, A., Gerami-Nejad, M., Paulson, C., Forche, A. & Berman, J., May 2008, In : Molecular Microbiology. 68, 3, p. 624-641 18 p.

Research output: Contribution to journalArticle

174 Scopus citations

Being a mouse in a man's world: What TMEV has taught us about human disease

Drescher, K. M. & Sosnowska, D., May 2 2008, In : Frontiers in Bioscience. 13, 10, p. 3775-3785 11 p.

Research output: Contribution to journalReview article

15 Scopus citations

Emergence of carbapenem resistance in Pseudomonas aeruginosa isolates from a patient with cystic fibrosis in the absence of carbapenem therapy

Wolter, D. J., Acquazzino, D., Goering, R. V., Sammut, P., Khalaf, N. & Hanson, N. D., Jun 15 2008, In : Clinical Infectious Diseases. 46, 12, p. e137-e141

Research output: Contribution to journalArticle

24 Scopus citations

Environmentally-relevant forms of the prion protein

Saunders, S. E., Bartz, J. C., Telling, G. C. & Bartelt-Hunt, S. L., Sep 1 2008, In : Environmental Science and Technology. 42, 17, p. 6573-6579 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

Epidemiology of European community-associated methicillin-resistant Staphylococcus aureus clonal complex 80 type IV strains isolated in Denmark from 1993 to 2004

Larsen, A. R., Böcher, S., Stegger, M., Goering, R., Pallesen, L. V. & Skov, R., Jan 1 2008, In : Journal of clinical microbiology. 46, 1, p. 62-68 7 p.

Research output: Contribution to journalArticle

67 Scopus citations

Evidence for Ku70/Ku80 association with full-length RAG1

Raval, P., Kriatchko, A. N., Kumar, S. & Swanson, P. C., Apr 1 2008, In : Nucleic Acids Research. 36, 6, p. 2060-2072 13 p.

Research output: Contribution to journalArticle

31 Scopus citations

Experimental Chronic Wasting Disease (CWD) in the Ferret

Sigurdson, C. J., Mathiason, C. K., Perrott, M. R., Eliason, G. A., Spraker, T. R., Glatzel, M., Manco, G., Bartz, J. C., Miller, M. W. & Hoover, E. A., May 1 2008, In : Journal of Comparative Pathology. 138, 4, p. 189-196 8 p.

Research output: Contribution to journalArticle

36 Scopus citations

Frequent emergence and limited geographic dispersal of methicillin- resistant Staphylococcus aureus

Nübel, U., Roumagnac, P., Feldkamp, M., Song, J. H., Ko, K. S., Huang, Y. C., Coombs, G., Ip, M., Westh, H., Skov, R., Struelens, M. J., Goering, R. V., Strommenger, B., Weller, A., Witte, W. & Achtman, M., Sep 16 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 37, p. 14130-14135 6 p.

Research output: Contribution to journalArticle

192 Scopus citations

Group B Coxsackieviruses: Preface

Oberste, S., Drescher, K. & Tracy, S., Dec 1 2008, Group B Coxsackieviruses. Tracy, S., Drescher, K. & Oberste, S. (eds.). p. v-vi (Current Topics in Microbiology and Immunology; vol. 323).

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

6 Scopus citations

Haplotype mapping of a diploid non-meiotic organism using existing and induced aneuploidies.

Legrand, M., Forche, A., Selmecki, A., Chan, C., Kirkpatrick, D. T. & Berman, J., Jan 2008, In : PLoS Genetics. 4, 1

Research output: Contribution to journalArticle

28 Scopus citations