Andrew Ekpenyong, PhD

Assistant Professor

  • 823 Citations
  • 14 h-Index
20072018
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Research Output 2007 2018

  • 823 Citations
  • 14 h-Index
  • 18 Article
  • 7 Conference contribution
  • 1 Letter
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Article
2018
47 Citations (Scopus)

A comparison of methods to assess cell mechanical properties

Wu, P. H., Aroush, D. R. B., Asnacios, A., Chen, W. C., Dokukin, M. E., Doss, B. L., Durand-Smet, P., Ekpenyong, A., Guck, J., Guz, N. V., Janmey, P. A., Lee, J. S. H., Moore, N. M., Ott, A., Poh, Y. C., Ros, R., Sander, M., Sokolov, I., Staunton, J. R., Wang, N. & 2 others, Whyte, G. & Wirtz, D., Jun 18 2018, (Accepted/In press) In : Nature Methods. p. 1-8 8 p.

Research output: Contribution to journalArticle

Mechanical properties
Cell adhesion
Rheology
Stretching
Monolayers
1 Citation (Scopus)

Fluorescence intensity modulation of CdSe/ZnS quantum dots assesses reactive oxygen species during chemotherapy and radiotherapy for cancer cells

Lee, B. H., Suresh, S. & Ekpenyong, A., Jan 1 2018, (Accepted/In press) In : Journal of Biophotonics. e201800172.

Research output: Contribution to journalArticle

Quantum Dots
Chemotherapy
Radiotherapy
chemotherapy
Semiconductor quantum dots
2017
13 Citations (Scopus)

Mechanical deformation induces depolarization of neutrophils

Ekpenyong, A., Toepfner, N., Fiddler, C., Herbig, M., Li, W., Cojoc, G., Summers, C., Guck, J. & Chilvers, E. R., Jun 1 2017, In : Science advances. 3, 6, e1602536.

Research output: Contribution to journalArticle

Neutrophils
Acute Lung Injury
Microcirculation

The value of mobile ultrasound services in rural communities in South-South Nigeria

Ikpeme, A., Ani, N., Ago, B., Effa, E., Kosoko-Lasaki, O. & Ekpenyong, A., Dec 15 2017, In : Open Access Macedonian Journal of Medical Sciences. 5, 7, p. 1011-1015 5 p.

Research output: Contribution to journalArticle

Rural Population
Nigeria
Clinical Pathology
Leiomyoma
2016
2 Citations (Scopus)

Chemotherapy impedes in vitro microcirculation and promotes migration of leukemic cells with impact on metastasis

Prathivadhi-Bhayankaram, S. V., Ning, J., Mimlitz, M., Taylor, C., Gross, E. M., Nichols, M. G., Guck, J. & Ekpenyong, A., Oct 28 2016, In : Biochemical and Biophysical Research Communications. 479, 4, p. 841-846 6 p.

Research output: Contribution to journalArticle

Microcirculation
Chemotherapy
Cell Movement
Cells
Neoplasm Metastasis
2015
14 Citations (Scopus)

Mechanotransduction in neutrophil activation and deactivation

Ekpenyong, A., Toepfner, N., Chilvers, E. R. & Guck, J., Nov 1 2015, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1853, 11, p. 3105-3116 12 p.

Research output: Contribution to journalArticle

Neutrophil Activation
Neutrophils
Mechanical Phenomena
Biophysics
Ion Channels
45 Citations (Scopus)

Myosin II activity softens cells in suspension

Chan, C. J., Ekpenyong, A., Golfier, S., Li, W., Chalut, K. J., Otto, O., Elgeti, J., Guck, J. & Lautenschläger, F., Apr 21 2015, In : Biophysical Journal. 108, 8, p. 1856-1869 14 p.

Research output: Contribution to journalArticle

Myosin Type II
Suspensions
Myosins
Mechanics
Microfluidics
235 Citations (Scopus)

Real-time deformability cytometry: On-the-fly cell mechanical phenotyping

Otto, O., Rosendahl, P., Mietke, A., Golfier, S., Herold, C., Klaue, D., Girardo, S., Pagliara, S., Ekpenyong, A., Jacobi, A., Wobus, M., Töpfner, N., Keyser, U. F., Mansfeld, J., Fischer-Friedrich, E. & Guck, J., Feb 26 2015, In : Nature Methods. 12, 3, p. 199-202 4 p.

Research output: Contribution to journalArticle

Formability
Cells
Flow cytometry
Biotechnology
Stem cells
19 Citations (Scopus)

Refractive index measurements of single, spherical cells using digital holographic microscopy

Schürmann, M., Scholze, J., Müller, P., Chan, C. J., Ekpenyong, A., Chalut, K. J. & Guck, J., 2015, In : Methods in Cell Biology. 125, p. 143-159 17 p.

Research output: Contribution to journalArticle

Refractometry
Microscopy
Light
Cell Communication
Retina
2014
49 Citations (Scopus)

Actin polymerization as a key innate immune effector mechanism to control Salmonella infection

Man, S. M., Ekpenyong, A., Tourlomousis, P., Achouri, S., Cammarota, E., Hughes, K., Rizzo, A., Ng, G., Wright, J. A., Cicuta, P., Guck, J. R. & Bryant, C. E., Dec 9 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 49, p. 17588-17593 6 p.

Research output: Contribution to journalArticle

Inflammasomes
Salmonella Infections
Polymerization
Actins
Macrophages
55 Citations (Scopus)

Separation of blood cells with differing deformability using deterministic lateral displacement

Holmes, D., Whyte, G., Bailey, J., Vergara-Irigaray, N., Ekpenyong, A., Guck, J. & Duke, T., Dec 6 2014, In : Interface Focus. 4, 6, 20140011.

Research output: Contribution to journalArticle

Formability
Blood Cells
Blood
Cells
Stiffness
2013
6 Citations (Scopus)

Elastic theory for the deformation of a solid or layered spheroid under axisymmetric loading

Boyde, L., Ekpenyong, A., Whyte, G. & Guck, J., Apr 2013, In : Acta Mechanica. 224, 4, p. 819-839 21 p.

Research output: Contribution to journalArticle

Poisson ratio
Elastic constants
Aspect ratio
Elasticity
Residual stresses
2012
79 Citations (Scopus)

Chromatin decondensation and nuclear softening accompany Nanog downregulation in embryonic stem cells

Chalut, K. J., Höpfler, M., Lautenschläger, F., Boyde, L., Chan, C. J., Ekpenyong, A., Martinez-Arias, A. & Guck, J., Nov 21 2012, In : Biophysical Journal. 103, 10, p. 2060-2070 11 p.

Research output: Contribution to journalArticle

Embryonic Stem Cells
Chromatin
Down-Regulation
Epigenomics
Histone Code
16 Citations (Scopus)

Comparison of stresses on homogeneous spheroids in the optical stretcher computed with geometrical optics and generalized Lorenz-Mie theory

Boyde, L., Ekpenyong, A., Whyte, G. & Guck, J., Nov 20 2012, In : Applied Optics. 51, 33, p. 7934-7944 11 p.

Research output: Contribution to journalArticle

Geometrical optics
spheroids
Mie scattering
geometrical optics
cells
50 Citations (Scopus)

Quantifying cellular differentiation by physical phenotype using digital holographic microscopy.

Chalut, K. J., Ekpenyong, A. E., Clegg, W. L., Melhuish, I. C. & Guck, J., Mar 2012, In : Integrative Biology. 4, 3, p. 280-284 5 p.

Research output: Contribution to journalArticle

Cell Differentiation
Microscopy
Microscopic examination
Myeloid Cells
Phenotype
97 Citations (Scopus)

Viscoelastic Properties of Differentiating Blood Cells Are Fate- and Function-Dependent

Ekpenyong, A., Whyte, G., Chalut, K., Pagliara, S., Lautenschläger, F., Fiddler, C., Paschke, S., Keyser, U. F., Chilvers, E. R. & Guck, J., Sep 27 2012, In : PLoS One. 7, 9, e45237.

Research output: Contribution to journalArticle

blood cells
Blood Cells
Blood
Cells
Myeloid Cells
2009
19 Citations (Scopus)

Determination of cell elasticity through hybrid ray optics and continuum mechanics modeling of cell deformation in the optical stretcher

Ekpenyong, A., Posey, C. L., Chaput, J. L., Burkart, A. K., Marquardt, M. M., Smith, T. J. & Nichols, M. G., Nov 10 2009, In : Applied Optics. 48, 32, p. 6344-6354 11 p.

Research output: Contribution to journalArticle

continuum mechanics
Continuum mechanics
geometrical optics
Elasticity
Optics
32 Citations (Scopus)

Diffraction imaging of spheres and melanoma cells with a microscope objective

Jacobs, K. M., Yang, L. V., Ding, J., Ekpenyong, A., Castellone, R., Lu, J. Q. & Hu, X. H., Sep 2009, In : Journal of Biophotonics. 2, 8-9, p. 521-527 7 p.

Research output: Contribution to journalArticle

Melanoma
Microscopes
Diffraction
microscopes
Imaging techniques