• 1709 Citations
  • 13 h-Index
20052019
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Research Output 2005 2019

  • 1709 Citations
  • 13 h-Index
  • 24 Article
  • 1 Review article
2019
Open Access
Enterobacter
Klebsiella pneumoniae
Genome
Enterobacteriaceae
Microbial Drug Resistance

Functional divergence of a global regulatory complex governing fungal filamentation

Polvi, E. J., Veri, A. O., Liu, Z., Hossain, S., Hyde, S., Kim, S. H., Tebbji, F., Sellam, A., Todd, R. T., Xie, J. L., Lin, Z. Y., Wong, C. J., Shapiro, R. S., Whiteway, M., Robbins, N., Gingras, A. C., Selmecki, A. & Cowen, L. E., Jan 1 2019, In : PLoS Genetics. 15, 1, p. e1007901

Research output: Contribution to journalArticle

morphogenesis
Morphogenesis
Candida albicans
divergence
Chromosomes, Human, Pair 6

Genome plasticity in Candida albicans is driven by long repeat sequences

Todd, R. T., Wikoff, T. D., Forche, A. & Selmecki, A., Jun 7 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
Candida
Candida albicans
Plasticity
Loss of Heterozygosity
Genes
1 Citation (Scopus)

Selection of Candida albicans trisomy during oropharyngeal infection results in a commensal-like phenotype

Forche, A., Solis, N. V., Swidergall, M., Thomas, R., Guyer, A., Beach, A., Cromie, G. A., Le, G. T., Lowell, E., Pavelka, N., Berman, J., Dudley, A. M., Selmecki, A. & Filler, S. G., May 1 2019, In : PLoS genetics. 15, 5, p. e1008137

Research output: Contribution to journalArticle

Open Access
trisomics
commensal
Candidiasis
Trisomy
Candida albicans
2018
1 Citation (Scopus)

Assembly of a complete genome sequence for Gemmata obscuriglobus reveals a novel prokaryotic rRNA operon gene architecture

Franke, J. D., Blomberg, W. R., Todd, R. T., Thomas, R. W. & Selmecki, A., May 21 2018, (Accepted/In press) In : Antonie van Leeuwenhoek, International Journal of General and Molecular Microbiology. p. 1-11 11 p.

Research output: Contribution to journalArticle

rRNA Operon
Operon
rRNA Genes
Genome
Gene Order

Flow Cytometry Analysis of Fungal Ploidy

Todd, R. T., Braverman, A. L. & Selmecki, A., Aug 1 2018, In : Current Protocols in Microbiology. 50, 1, e58.

Research output: Contribution to journalArticle

Ploidies
Flow Cytometry
Fungal Drug Resistance
Single-Cell Analysis
Biological Phenomena
4 Citations (Scopus)

Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs

Mount, H. OC., Revie, N. M., Todd, R. T., Anstett, K., Collins, C., Costanzo, M., Boone, C., Robbins, N., Selmecki, A. & Cowen, L. E., Apr 1 2018, In : PLoS Genetics. 14, 4, e1007319.

Research output: Contribution to journalArticle

azoles
Azoles
antifungal agents
resistance mechanisms
genetic techniques and protocols

Spindle dynamics model explains chromosome loss rates in yeast polyploid cells

Jelenic, I., Selmecki, A., Laan, L. & Pavin, N., Aug 6 2018, In : Frontiers in Genetics. 9, AUG, 296.

Research output: Contribution to journalArticle

Polyploidy
Chromosomes
Yeasts
Ploidies
Saccharomyces cerevisiae
2017
12 Citations (Scopus)

Ploidy variation in fungi: Polyploidy, aneuploidy, and genome evolution

Todd, R. T., Forche, A. & Selmecki, A., Jul 1 2017, In : Microbiology spectrum. 5, 4, FUNK-0051-2016.

Research output: Contribution to journalArticle

Genome Size
polyploidy
Aptitude
Polyploidy
ploidy
11 Citations (Scopus)

The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation

Xie, J. L., Qin, L., Miao, Z., Grys, B. T., Diaz, J. D. L. C., Ting, K., Krieger, J. R., Tong, J., Tan, K., Leach, M. D., Ketela, T., Moran, M. F., Krysan, D. J., Boone, C., Andrews, B. J., Selmecki, A., Ho Wong, K., Robbins, N. & Cowen, L. E., Dec 1 2017, In : Nature Communications. 8, 1, 499.

Research output: Contribution to journalArticle

Candida
Candida albicans
Drug Resistance
Echinocandins
Cell Cycle
6 Citations (Scopus)

The Influence of Polyploidy on the Evolution of Yeast Grown in a Sub-Optimal Carbon Source

Scott, A. L., Richmond, P. A., Dowell, R. D. & Selmecki, A., Oct 1 2017, In : Molecular Biology and Evolution. 34, 10, p. 2690-2703 14 p.

Research output: Contribution to journalArticle

polyploidy
Polyploidy
yeast
mutation
Carbon
2015
134 Citations (Scopus)

Polyploidy can drive rapid adaptation in yeast

Selmecki, A., Maruvka, Y. E., Richmond, P. A., Guillet, M., Shoresh, N., Sorenson, A. L., De, S., Kishony, R., Michor, F., Dowell, R. & Pellman, D., Mar 19 2015, In : Nature. 519, 7543, p. 349-351 3 p.

Research output: Contribution to journalArticle

Polyploidy
Yeasts
Tetraploidy
Genome
Mutation
2011
19 Citations (Scopus)

Rad52 function prevents chromosome loss and truncation in Candida albicans

Andaluz, E., Bellido, A., Gómez-Raja, J., Selmecki, A., Bouchonville, K., Calderone, R., Berman, J. & Larriba, G., Mar 2011, In : Molecular Microbiology. 79, 6, p. 1462-1482 21 p.

Research output: Contribution to journalArticle

Loss of Heterozygosity
Candida albicans
Chromosomal Instability
Chromosomes
Mutation
2010
120 Citations (Scopus)

Genomic plasticity of the human fungal pathogen Candida albicans

Selmecki, A., Forche, A. & Berman, J., Jul 2010, In : Eukaryotic Cell. 9, 7, p. 991-1008 18 p.

Research output: Contribution to journalReview article

Candida albicans
Aneuploidy
Chromosomes
Genome
Polyploidy
4 Citations (Scopus)

Low dosage of histone H4 leads to growth defects and morphological changes in candida albicans

Zacchi, L. F., Selmecki, A., Berman, J. & Davis, D. A., 2010, In : PLoS One. 5, 5, e10629.

Research output: Contribution to journalArticle

Candida
Candida albicans
histones
Histones
Defects
2009
142 Citations (Scopus)

Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance

Selmecki, A., Dulmage, K., Cowen, L. E., Anderson, J. B. & Berman, J., Oct 2009, In : PLoS Genetics. 5, 10, e1000705.

Research output: Contribution to journalArticle

Fungal Drug Resistance
drug resistance
antifungal agents
fluconazole
Fluconazole
40 Citations (Scopus)

Aneuploid chromosomes are highly unstable during DNA transformation of candida albicans∇

Bouchonville, K., Forche, A., Tang, K. E. S., Selmecki, A. & Berman, J., Oct 2009, In : Eukaryotic Cell. 8, 10, p. 1554-1566 13 p.

Research output: Contribution to journalArticle

Aneuploidy
Candida albicans
Chromosomes
DNA
Hot Temperature
75 Citations (Scopus)

Evolution in Candida albicans populations during a single passage through a mouse host

Forche, A., Magee, P. T., Selmecki, A., Berman, J. & May, G., Jul 2009, In : Genetics. 182, 3, p. 799-811 13 p.

Research output: Contribution to journalArticle

Candida albicans
Growth
Population
Loss of Heterozygosity
Population Growth
94 Citations (Scopus)

Neocentromeres form efficiently at multiple possible loci in candida albicans

Ketel, C., Wang, H. S. W., McClellan, M., Bouchonville, K., Selmecki, A., Lahav, T., Gerami-Nejad, M. & Berman, J., Mar 2009, In : PLoS Genetics. 5, 3

Research output: Contribution to journalArticle

Centromere
centromeres
Candida albicans
chromosomes
DNA
2008
160 Citations (Scopus)

An isochromosome confers drug resistance in vivo by amplification of two genes, ERG11 and TAC1

Selmecki, A., Gerami-Nejad, M., Paulson, C., Forche, A. & Berman, J., May 2008, In : Molecular Microbiology. 68, 3, p. 624-641 18 p.

Research output: Contribution to journalArticle

Isochromosomes
Fluconazole
Gene Amplification
Drug Resistance
Azoles
19 Citations (Scopus)

Haplotype mapping of a diploid non-meiotic organism using existing and induced aneuploidies.

Legrand, M., Forche, A., Selmecki, A., Chan, C., Kirkpatrick, D. T. & Berman, J., Jan 2008, In : PLoS Genetics. 4, 1

Research output: Contribution to journalArticle

aneuploidy
Aneuploidy
Diploidy
Haplotypes
haplotypes
2007
183 Citations (Scopus)

Genotypic evolution of azole resistance mechanisms in sequential Candida albicans isolates

Coste, A., Selmecki, A., Forche, A., Diogo, D., Bougnoux, M. E., D'Enfert, C., Berman, J. & Sanglard, D., Oct 2007, In : Eukaryotic Cell. 6, 10, p. 1889-1904 16 p.

Research output: Contribution to journalArticle

azoles
Azoles
Candida albicans
resistance mechanisms
Chromosomes, Human, Pair 5
2006
211 Citations (Scopus)

A mutation in Tac1p, a transcription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans

Coste, A., Turner, V., Ischer, F., Morschhäuser, J., Forche, A., Selmecki, A., Berman, J., Bille, J. & Sanglard, D., Apr 2006, In : Genetics. 172, 4, p. 2139-2156 18 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 5
Loss of Heterozygosity
Candida albicans
Transcription Factors
Alleles
365 Citations (Scopus)

Aneuploidy and isochromosome formation in drug-resistant Candida albicans

Selmecki, A., Forche, A. & Berman, J., Jul 21 2006, In : Science. 313, 5785, p. 367-370 4 p.

Research output: Contribution to journalArticle

Isochromosomes
Aneuploidy
Candida albicans
Azoles
Chromosomes, Human, Pair 5
2005
108 Citations (Scopus)

Comparative genome hybridization reveals widespread aneuploidy in Candida albicans laboratory strains

Selmecki, A., Bergmann, S. & Berman, J., Mar 2005, In : Molecular Microbiology. 55, 5, p. 1553-1565 13 p.

Research output: Contribution to journalArticle

carboxyamido-triazole
Comparative Genomic Hybridization
Aneuploidy
Candida albicans
Trisomy