• 896 Citations
  • 16 h-Index
19952019
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Research Output 1995 2019

  • 896 Citations
  • 16 h-Index
  • 63 Article
  • 8 Chapter
  • 5 Review article
2019

Interaction between hydrogen sulfide, nitric oxide, and carbon monoxide pathways in the bovine isolated retina

Kulkarni-Chitnis, M., Mitchell-Bush, L., Belford, R., Robinson, J., Opere, C. A., Ohia, S. E. & Mbye, Y. F. N., Jan 1 2019, In : AIMS Neuroscience. 6, 3, p. 104-115 12 p.

Research output: Contribution to journalArticle

Open Access
Hydrogen Sulfide
Carbon Monoxide
Retina
Nitric Oxide
Gasotransmitters

Preparation, Characterization and Antioxidant Evaluation of Poorly Soluble Polyphenol-Loaded Nanoparticles for Cataract Treatment

Vora, D., Heruye, S., Kumari, D., Opere, C. A. & Chauhan, H., Jul 1 2019, In : AAPS PharmSciTech. 20, 5, 163.

Research output: Contribution to journalArticle

cataract
Polyphenols
nanoparticles
Nanoparticles
Cataract

Standardization of a new method for assessing the development of cataract in cultured bovine lenses

Heruye, S., Maffofou N., L. N., Singh, N. U., Munt, D., Njie-Mbye, Y. F., Ohia, S. E. & Opere, C. A., Jul 1 2019, In : Journal of Pharmacological and Toxicological Methods. 98, 106592.

Research output: Contribution to journalArticle

Cataract
Standardization
Lenses
Cysteine
Superoxide Dismutase
2018
3 Citations (Scopus)

Comparative Effects of Hydrogen Sulfide-Releasing Compounds on [3H]D-Aspartate Release from Bovine Isolated Retinae

Bankhele, P., Salvi, A., Jamil, J., Njie-Mbye, F., Ohia, S. & Opere, C. A., Jan 20 2018, (Accepted/In press) In : Neurochemical Research. p. 1-10 10 p.

Research output: Contribution to journalArticle

D-Aspartic Acid
Hydrogen Sulfide
Cysteine
Retina
Acetylcysteine

Pharmacology of serotonin receptors causing contraction of isolated bovine posterior ciliary arteries: Role in ocular blood flow

Njie-Mbye, Y. F., Robinson, J., Mitchell-Bush, L., McKoy, M., Opere, C. A., Ohia, S. E. & Sharif, N., Jan 1 2018, In : Journal of Ocular Pharmacology and Therapeutics. 34, 1-2, p. 134-140 7 p.

Research output: Contribution to journalArticle

Ciliary Arteries
Serotonin Receptors
Pharmacology
Serotonin 5-HT2 Receptor Antagonists
Serotonin
3 Citations (Scopus)

Regulation of aqueous humor dynamics by hydrogen sulfide: Potential role in glaucoma pharmacotherapy

Ohia, S. E., Robinson, J., Mitchell, L., Ngele, K. K., Heruye, S., Opere, C. A. & Njie-Mbye, Y. F., Jan 1 2018, In : Journal of Ocular Pharmacology and Therapeutics. 34, 1-2, p. 61-69 9 p.

Research output: Contribution to journalArticle

Hydrogen Sulfide
Aqueous Humor
Glaucoma
Gases
Cystathionine
2 Citations (Scopus)

Regulation of excitatory amino acid transmission in the retina: Studies on neuroprotection

Opere, C. A., Heruye, S., Njie-Mbye, Y. F., Ohia, S. E. & Sharif, N. A., Jan 1 2018, In : Journal of Ocular Pharmacology and Therapeutics. 34, 1-2, p. 107-118 12 p.

Research output: Contribution to journalArticle

Excitatory Amino Acids
Retina
Retinal Degeneration
Hypoglycemia
eglumetad

Serotonin-2B/2C receptors mediate bovine ciliary muscle contraction: Role in intraocular pressure regulation

Ohia, S. E., Njie-Mbye, Y. F., Robinson, J., Mitchell, L., McKoy, M., Opere, C. A. & Sharif, N. A., Jan 1 2018, In : Journal of Ocular Pharmacology and Therapeutics. 34, 1-2, p. 70-75 6 p.

Research output: Contribution to journalArticle

Receptor, Serotonin, 5-HT2B
Receptor, Serotonin, 5-HT2C
Muscle Contraction
Intraocular Pressure
Muscles
2017
3 Citations (Scopus)

Effects of Hydrogen Sulfide-Releasing Compounds on Aqueous Humor Outflow Facility in Porcine Ocular Anterior Segments, Ex Vivo

Robinson, J., Okoro, E., Ezuedu, C., Bush, L., Opere, C. A., Ohia, S. E. & Njie-Mbye, Y. F., Mar 1 2017, In : Journal of Ocular Pharmacology and Therapeutics. 33, 2, p. 91-97 7 p.

Research output: Contribution to journalArticle

Hydrogen Sulfide
Aqueous Humor
Swine
Glyburide
Cysteine
8 Citations (Scopus)

Sustained-Release Delivery System of a Slow Hydrogen Sulfide Donor, GYY 4137, for Potential Application in Glaucoma

Patil, A., Singh, S., Opere, C. A. & Dash, A. K., Jan 18 2017, (Accepted/In press) In : AAPS PharmSciTech. p. 1-12 12 p.

Research output: Contribution to journalArticle

Hydrogen Sulfide
glaucoma
hydrogen sulfide
Glaucoma
polymers
2016
12 Citations (Scopus)

Effect of hydrogen sulfide donors on intraocular pressure in rabbits

Salvi, A., Bankhele, P., Jamil, J., Chitnis, M. K., Njie-Mbye, Y. F., Ohia, S. E. & Opere, C. A., Jul 1 2016, In : Journal of Ocular Pharmacology and Therapeutics. 32, 6, p. 371-375 5 p.

Research output: Contribution to journalArticle

Hydrogen Sulfide
Intraocular Pressure
Rabbits
latanoprost
Cysteine

Optic neuritis: A brief review

Opere, C. A., O’Brien, K. K. & Elhaj, M. H., Jan 1 2016, U.S. Pharmacist, 41, 1, p. 35-40 6 p.

Research output: Contribution to specialist publicationArticle

Optic Neuritis
Optics
Multiple Sclerosis
Optic Nerve
Adrenal Cortex Hormones
13 Citations (Scopus)

Pharmacological Actions of Hydrogen Sulfide Donors on Sympathetic Neurotransmission in the Bovine Anterior Uvea, In Vitro

Salvi, A., Bankhele, P., Jamil, J. M., Kulkarni-Chitnis, M., Njie-Mbye, Y. F., Ohia, S. E. & Opere, C. A., May 1 2016, In : Neurochemical Research. 41, 5, p. 1020-1028 9 p.

Research output: Contribution to journalArticle

Uvea
Hydrogen Sulfide
Ciliary Body
Iris
Synaptic Transmission
2015
16 Citations (Scopus)

Inhibitory action of novel hydrogen sulfide donors on bovine isolated posterior ciliary arteries

Kulkarni-Chitnis, M., Njie-Mbye, Y. F., Mitchell, L., Robinson, J., Whiteman, M., Wood, M. E., Opere, C. A. & Ohia, S. E., May 1 2015, In : Experimental Eye Research. 134, p. 73-79 7 p.

Research output: Contribution to journalArticle

Ciliary Arteries
Hydrogen Sulfide
KATP Channels
Phenylephrine
Flurbiprofen

Preventive HIV vaccines: Progress and challenges

Bossou, A. R., Castillo, S., O’Brien, K. K., Opere, C. A. & Destache, C. J., Oct 16 2015, U.S. Pharmacist, 40, 10, p. 46-50 5 p.

Research output: Contribution to specialist publicationArticle

AIDS Vaccines
HIV Infections
Vaccines
HIV
Patient Compliance
2014
7 Citations (Scopus)

In vitro-controlled release delivery system for hydrogen sulfide donor

Ali, H., Opere, C. A. & Singh, S., 2014, In : AAPS PharmSciTech. 15, 4, p. 910-919 10 p.

Research output: Contribution to journalArticle

Hydrogen Sulfide
hydrogen sulfide
polymers
Polymers
sodium sulfide
9 Citations (Scopus)

Role of the Non-enzymatic Metabolite of Eicosapentaenoic Acid, 5-epi-5-F3t-Isoprostane in the Regulation of [3H]d-Aspartate Release in Isolated Bovine Retina

Jamil, J., Bankhele, P., Salvi, A., Mannix, J. E., Oger, C., Guy, A., Galano, J. M., Durand, T., Njie-Mbye, Y. F., Ohia, S. E. & Opere, C. A., Nov 25 2014, In : Neurochemical Research. 39, 12, p. 2360-2369 10 p.

Research output: Contribution to journalArticle

Isoprostanes
Eicosapentaenoic Acid
Metabolites
Aspartic Acid
Neurotransmitter Agents
2013
54 Citations (Scopus)

Isoprostanes and neuroprostanes: Total synthesis, biological activity and biomarkers of oxidative stress in humans

Galano, J. M., Mas, E., Barden, A., Mori, T. A., Signorini, C., De Felice, C., Barrett, A., Opere, C. A., Pinot, E., Schwedhelm, E., Benndorf, R., Roy, J., Le Guennec, J. Y., Oger, C. & Durand, T., 2013, In : Prostaglandins and Other Lipid Mediators. 107, p. 95-102 8 p.

Research output: Contribution to journalReview article

Neuroprostanes
Isoprostanes
Oxidative stress
Docosahexaenoic Acids
Biomarkers
29 Citations (Scopus)

Lipid peroxidation: Pathophysiological and pharmacological implications in the eye

Njie-Mbye, Y. F., Kulkarni-Chitnis, M., Opere, C. A., Barrett, A. & Ohia, S. E., 2013, In : Frontiers in Physiology. 4 DEC, Article 366.

Research output: Contribution to journalReview article

Lipid Peroxidation
Peroxides
Retina
Pharmacology
Isoprostanes

Ocular Health, Vision, and a Healthy Diet

Ohia, S. E., Opere, C. A., Kulkarni, M. & Barett, A., Oct 2013, Inflammation, Advancing Age and Nutrition: Research and Clinical Interventions. Elsevier Inc., p. 267-277 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Health
Macular Degeneration
Diabetic Retinopathy
Glaucoma
Cataract
30 Citations (Scopus)

Pharmacological actions of the slow release hydrogen sulfide donor GYY4137 on phenylephrine-induced tone in isolated bovine ciliary artery

Chitnis, M. K., Njie-Mbye, Y. F., Opere, C. A., Wood, M. E., Whiteman, M. & Ohia, S. E., Nov 2013, In : Experimental Eye Research. 116, p. 350-354 5 p.

Research output: Contribution to journalArticle

Ciliary Arteries
Hydrogen Sulfide
Phenylephrine
Pharmacology
Cystathionine
2012
8 Citations (Scopus)

Hydrogen sulfide: Role in ion channel and transporter modulation in the eye

Njie-Mbye, Y. F., Opere, C. A., Chitnis, M. & Ohia, S. E., 2012, In : Frontiers in Physiology. 3 JUL, Article 295.

Research output: Contribution to journalReview article

Hydrogen Sulfide
Ion Channels
Gasotransmitters
Physiological Phenomena
Antiporters
19 Citations (Scopus)

Mechanism of action of hydrogen sulfide on cyclic AMP formation in rat retinal pigment epithelial cells

Njie-Mbye, Y. F., Kulkarni, M., Opere, C. A. & Ohia, S. E., May 2012, In : Experimental Eye Research. 98, 1, p. 16-22 7 p.

Research output: Contribution to journalArticle

Hydrogen Sulfide
Retinal Pigments
Cyclic AMP
Epithelial Cells
Glyburide
9 Citations (Scopus)

Regulation of [ 3H]D-aspartate release by the 5-F 2t-isoprostane and its 5-epimer in isolated bovine retina

Jamil, J., Wright, A., Harrison, NC., Kegey, E., Flowers, A. F., Flyod, N. J., Kotera, C., Guy, A., Galano, J. M., Durand, T., Njie-Mbye, Y. F., Ohia, S. E. & Opere, C. A., Mar 2012, In : Neurochemical Research. 37, 3, p. 574-582 9 p.

Research output: Contribution to journalArticle

D-Aspartic Acid
Retina
Neurotransmitter Agents
Prostaglandins
Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide
2011

AQP1, aquaporin 1

Opere, C. A. & Opere, D., 2011, xPharm: The Comprehensive Pharmacology Reference. Elsevier Inc., p. 1-9 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Aquaporin 1
Aquaporins

AQP2, aquaporin 2

Opere, C. A., 2011, xPharm: The Comprehensive Pharmacology Reference. Elsevier Inc., p. 1-9 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Aquaporin 2
Aquaporins

AQP4, aquaporin 4

Braig, E. & Opere, C. A., 2011, xPharm: The Comprehensive Pharmacology Reference. Elsevier Inc., p. 1-7 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Aquaporin 4
Aquaporins
Cell Membrane
Water
Proteins

Aquaporin family

Braig, E. & Opere, C. A., 2011, xPharm: The Comprehensive Pharmacology Reference. Elsevier Inc., p. 1-12 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Aquaporins
Cell Membrane
Water
Proteins

Bretylium

Opere, C. A., 2011, xPharm: The Comprehensive Pharmacology Reference. Elsevier Inc., p. 1-8 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Quaternary Ammonium Compounds
bretylium
20 Citations (Scopus)

Endogenous production of hydrogen sulfide in isolated bovine eye

Kulkarni, M., Njie-Mbye, Y. F., Okpobiri, I., Zhao, M., Opere, C. A. & Ohia, S. E., Aug 2011, In : Neurochemical Research. 36, 8, p. 1540-1545 6 p.

Research output: Contribution to journalArticle

Hydrogen Sulfide
Methionine
Cysteine
Retina
Gasotransmitters

Procainamide

Opere, C. A., 2011, xPharm: The Comprehensive Pharmacology Reference. Elsevier Inc., p. 1-8 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Procainamide
1 Citation (Scopus)

Understanding Diabetic Retinopathy

Opere, C. A., O'Brien, K. K. & Shea, J. L., Apr 2011, U.S. Pharmacist, 36, 4.

Research output: Contribution to specialist publicationArticle

Diabetic Retinopathy
2010
18 Citations (Scopus)

Effect of hydrogen sulfide on cyclic AMP production in isolated bovine and porcine neural retinae

Njie-Mbye, Y. F., Bongmba, O. Y. N., Onyema, C. C., Chitnis, A., Kulkarni, M., Opere, C. A., Leday, A. M. & Ohia, S. E., Mar 2010, In : Neurochemical Research. 35, 3, p. 487-494 8 p.

Research output: Contribution to journalArticle

Hydrogen Sulfide
Cyclic AMP
Retina
Swine
Colforsin
14 Citations (Scopus)

Role of hydrogen sulfide production in inhibitory action of L-cysteine on isolated porcine irides

Ohia, S. E., Opere, C. A., Monjok, E. M., Kouamou, G., Leday, A. M. & Njie-Mbye, Y. F., May 2010, In : Current Eye Research. 35, 5, p. 402-407 6 p.

Research output: Contribution to journalArticle

Hydrogen Sulfide
Iris
Cysteine
Swine
Cystathionine
2009
62 Citations (Scopus)

Effect of hydrogen sulfide on sympathetic neurotransmission and catecholamine levels in isolated porcine iris-ciliary body

Kulkarni, K. H., Monjok, E. M., Zeyssig, R., Kouamou, G., Bongmba, O. N., Opere, C. A., Njie, Y. F. & Ohia, S. E., Mar 2009, In : Neurochemical Research. 34, 3, p. 400-406 7 p.

Research output: Contribution to journalArticle

Hydrogen Sulfide
Ciliary Body
Iris
Synaptic Transmission
Catecholamines
17 Citations (Scopus)

Regulation of [3H] d-aspartate release from mammalian isolated retinae by hydrogen sulfide

Opere, C. A., Monjok, E. M., Kulkarni, K. H., Njie, Y. F. & Ohia, S. E., 2009, In : Neurochemical Research. 34, 11, p. 1962-1968 7 p.

Research output: Contribution to journalArticle

Hydrogen Sulfide
Aspartic Acid
Retina
Swine
Synaptic Transmission
8 Citations (Scopus)
Prostaglandins
Neurotransmitter Agents
Amino Acids
Glutamine
Glycine
2008
30 Citations (Scopus)

Inhibitory action of hydrogen sulfide on muscarinic receptor-induced contraction of isolated porcine irides

Monjok, E. M., Kulkarni, K. H., Kouamou, G., McKoy, M., Opere, C. A., Bongmba, O. N., Njie, Y. F. & Ohia, S. E., Dec 10 2008, In : Experimental Eye Research. 87, 6, p. 612-616 5 p.

Research output: Contribution to journalArticle

Hydrogen Sulfide
Muscarinic Receptors
Iris
Cystathionine
Swine
5 Citations (Scopus)

Prejunctional inhibitory effects of isoprostanes on dopaminergic neurotransmission in bovine retinae, in vitro

Liu, H., Zhao, M. & Opere, C. A., Jan 2008, In : Neurochemical Research. 33, 1, p. 37-42 6 p.

Research output: Contribution to journalArticle

Isoprostanes
Synaptic Transmission
Retina
Dopamine
Dinoprost
9 Citations (Scopus)

Regulation of neurotransmitter release from ocular tissues by isoprostanes

Opere, C. A., Ford, K., Zhao, M. & Ohia, S. E., Nov 2008, In : Methods and Findings in Experimental and Clinical Pharmacology. 30, 9, p. 697-701 5 p.

Research output: Contribution to journalReview article

8-epi-prostaglandin F2alpha
Isoprostanes
Thromboxane Receptors
Neurotransmitter Agents
Uvea
2 Citations (Scopus)
Amino Acids
Isoprostanes
Neurotransmitter Agents
Retina
Glutamic Acid
2007

Role of neurotransmitters in obesity regulation

Ohia, S. E. & Opere, C. A., Jan 1 2007, Obesity: Epidemiology, Pathophysiology, and Prevention. CRC Press, p. 71-80 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Neuropeptides
Neurotransmitter Agents
Obesity
Serotonin
Eating
2006
20 Citations (Scopus)

Inhibition of potassium- and ischemia-evoked [3H] D-aspartate release from isolated bovine retina by cannabinoids

Opere, C. A., Zheng, W., Zhao, M., Lee, J., Kulkarni, K. & Ohia, S., Aug 1 2006, In : Current Eye Research. 31, 7-8, p. 645-653 9 p.

Research output: Contribution to journalArticle

D-Aspartic Acid
Cannabinoid Receptor CB1
Cannabinoids
Retina
Potassium
1 Citation (Scopus)

Regulation of norepinephrine release from isolated bovine irides by histamine

Kulkarni, K. H., Opere, C. A., LeDay, A. M., Shara, M. A. & Ohia, S. E., Jul 2006, In : Neurochemical Research. 31, 7, p. 891-897 7 p.

Research output: Contribution to journalArticle

Histamine Receptors
Histamine Agonists
Iris
Histamine
Methylhistamines
2005
19 Citations (Scopus)

Dual effect of isoprostanes on the release of [3H]D-aspartate from isolated bovine retinae: Role of arachidonic acid metabolites

Opere, C. A., Zheng, W. D., Huang, J., Adewale, A., Kruglet, M. & Ohia, S. E., Jan 2005, In : Neurochemical Research. 30, 1, p. 129-137 9 p.

Research output: Contribution to journalArticle

Isoprostanes
D-Aspartic Acid
Metabolites
Arachidonic Acid
8-epi-prostaglandin F2alpha
4 Citations (Scopus)

Ocular pharmacology of bicyclic hexahydroaporphines

Ohia, S. E., Zhan, G. L., LeDay, A. M., Opere, C. A., Kulkarni, K. H., Harris, L. C. & Roche, V. F., Mar 2005, In : Methods and Findings in Experimental and Clinical Pharmacology. 27, 2, p. 87-93 7 p.

Research output: Contribution to journalArticle

Intraocular Pressure
Pharmacology
Carbachol
Iris
Nitric Oxide
104 Citations (Scopus)

Pharmacological consequences of oxidative stress in ocular tissues

Ohia, S. E., Opere, C. A. & Leday, A. M., Nov 11 2005, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 579, 1-2, p. 22-36 15 p.

Research output: Contribution to journalReview article

Peroxides
Oxidative Stress
Uvea
Pharmacology
Isoprostanes
2004
11 Citations (Scopus)

Arachidonic acid metabolites and peroxide-induced inhibition of [ 3H]D-aspartate release from bovine isolated retinae

LeDay, A. M., Kulkarni, K. H., Opere, C. A. & Ohia, S. E., May 2004, In : Current Eye Research. 28, 5, p. 367-372 6 p.

Research output: Contribution to journalArticle

D-Aspartic Acid
Peroxides
Arachidonic Acid
Retina
Dinoprost
2 Citations (Scopus)

Effect of Peroxides on [3H]D-Aspartate Release from Bovine Isolated Retinae

LeDay, A. M., Awe, S. O., Kulkarni, K., Harris, L. C., Opere, C. A., Dash, A. K. & Ohia, S. E., Apr 2004, In : Neurochemical Research. 29, 4, p. 811-818 8 p.

Research output: Contribution to journalArticle

D-Aspartic Acid
Peroxides
Retina
Glutamic Acid
Vitreous Body
2003
4 Citations (Scopus)

Effect of Hydrogen Peroxide on Amino Acid Concentrations in Bovine Retina and Vitreous Humor, Ex Vivo

LeDay, A. M., Ganguly, S., Kulk̃arni, K. H., Dash, A., Opere, C. A. & Ohia, S. E., Nov 2003, In : Methods and Findings in Experimental and Clinical Pharmacology. 25, 9, p. 695-701 7 p.

Research output: Contribution to journalArticle

Vitreous Body
Glycine
Hydrogen Peroxide
Retina
Glutamic Acid