• 896 Citations
  • 16 h-Index
19952019
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Research Output 1995 2019

  • 896 Citations
  • 16 h-Index
  • 63 Article
  • 8 Chapter
  • 5 Review article
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Article
2019

Interaction between hydrogen sulfide, nitric oxide, and carbon monoxide pathways in the bovine isolated retina

Kulkarni-Chitnis, M., Mitchell-Bush, L., Belford, R., Robinson, J., Opere, C. A., Ohia, S. E. & Mbye, Y. F. N., Jan 1 2019, In : AIMS Neuroscience. 6, 3, p. 104-115 12 p.

Research output: Contribution to journalArticle

Open Access
Hydrogen Sulfide
Carbon Monoxide
Retina
Nitric Oxide
Gasotransmitters

Preparation, Characterization and Antioxidant Evaluation of Poorly Soluble Polyphenol-Loaded Nanoparticles for Cataract Treatment

Vora, D., Heruye, S., Kumari, D., Opere, C. A. & Chauhan, H., Jul 1 2019, In : AAPS PharmSciTech. 20, 5, 163.

Research output: Contribution to journalArticle

cataract
Polyphenols
nanoparticles
Nanoparticles
Cataract

Standardization of a new method for assessing the development of cataract in cultured bovine lenses

Heruye, S., Maffofou N., L. N., Singh, N. U., Munt, D., Njie-Mbye, Y. F., Ohia, S. E. & Opere, C. A., Jul 1 2019, In : Journal of Pharmacological and Toxicological Methods. 98, 106592.

Research output: Contribution to journalArticle

Cataract
Standardization
Lenses
Cysteine
Superoxide Dismutase
2018
3 Citations (Scopus)

Comparative Effects of Hydrogen Sulfide-Releasing Compounds on [3H]D-Aspartate Release from Bovine Isolated Retinae

Bankhele, P., Salvi, A., Jamil, J., Njie-Mbye, F., Ohia, S. & Opere, C. A., Jan 20 2018, (Accepted/In press) In : Neurochemical Research. p. 1-10 10 p.

Research output: Contribution to journalArticle

D-Aspartic Acid
Hydrogen Sulfide
Cysteine
Retina
Acetylcysteine

Pharmacology of serotonin receptors causing contraction of isolated bovine posterior ciliary arteries: Role in ocular blood flow

Njie-Mbye, Y. F., Robinson, J., Mitchell-Bush, L., McKoy, M., Opere, C. A., Ohia, S. E. & Sharif, N., Jan 1 2018, In : Journal of Ocular Pharmacology and Therapeutics. 34, 1-2, p. 134-140 7 p.

Research output: Contribution to journalArticle

Ciliary Arteries
Serotonin Receptors
Pharmacology
Serotonin 5-HT2 Receptor Antagonists
Serotonin
3 Citations (Scopus)

Regulation of aqueous humor dynamics by hydrogen sulfide: Potential role in glaucoma pharmacotherapy

Ohia, S. E., Robinson, J., Mitchell, L., Ngele, K. K., Heruye, S., Opere, C. A. & Njie-Mbye, Y. F., Jan 1 2018, In : Journal of Ocular Pharmacology and Therapeutics. 34, 1-2, p. 61-69 9 p.

Research output: Contribution to journalArticle

Hydrogen Sulfide
Aqueous Humor
Glaucoma
Gases
Cystathionine
2 Citations (Scopus)

Regulation of excitatory amino acid transmission in the retina: Studies on neuroprotection

Opere, C. A., Heruye, S., Njie-Mbye, Y. F., Ohia, S. E. & Sharif, N. A., Jan 1 2018, In : Journal of Ocular Pharmacology and Therapeutics. 34, 1-2, p. 107-118 12 p.

Research output: Contribution to journalArticle

Excitatory Amino Acids
Retina
Retinal Degeneration
Hypoglycemia
eglumetad

Serotonin-2B/2C receptors mediate bovine ciliary muscle contraction: Role in intraocular pressure regulation

Ohia, S. E., Njie-Mbye, Y. F., Robinson, J., Mitchell, L., McKoy, M., Opere, C. A. & Sharif, N. A., Jan 1 2018, In : Journal of Ocular Pharmacology and Therapeutics. 34, 1-2, p. 70-75 6 p.

Research output: Contribution to journalArticle

Receptor, Serotonin, 5-HT2B
Receptor, Serotonin, 5-HT2C
Muscle Contraction
Intraocular Pressure
Muscles
2017
3 Citations (Scopus)

Effects of Hydrogen Sulfide-Releasing Compounds on Aqueous Humor Outflow Facility in Porcine Ocular Anterior Segments, Ex Vivo

Robinson, J., Okoro, E., Ezuedu, C., Bush, L., Opere, C. A., Ohia, S. E. & Njie-Mbye, Y. F., Mar 1 2017, In : Journal of Ocular Pharmacology and Therapeutics. 33, 2, p. 91-97 7 p.

Research output: Contribution to journalArticle

Hydrogen Sulfide
Aqueous Humor
Swine
Glyburide
Cysteine
8 Citations (Scopus)

Sustained-Release Delivery System of a Slow Hydrogen Sulfide Donor, GYY 4137, for Potential Application in Glaucoma

Patil, A., Singh, S., Opere, C. A. & Dash, A. K., Jan 18 2017, (Accepted/In press) In : AAPS PharmSciTech. p. 1-12 12 p.

Research output: Contribution to journalArticle

Hydrogen Sulfide
glaucoma
hydrogen sulfide
Glaucoma
polymers
2016
12 Citations (Scopus)

Effect of hydrogen sulfide donors on intraocular pressure in rabbits

Salvi, A., Bankhele, P., Jamil, J., Chitnis, M. K., Njie-Mbye, Y. F., Ohia, S. E. & Opere, C. A., Jul 1 2016, In : Journal of Ocular Pharmacology and Therapeutics. 32, 6, p. 371-375 5 p.

Research output: Contribution to journalArticle

Hydrogen Sulfide
Intraocular Pressure
Rabbits
latanoprost
Cysteine

Optic neuritis: A brief review

Opere, C. A., O’Brien, K. K. & Elhaj, M. H., Jan 1 2016, U.S. Pharmacist, 41, 1, p. 35-40 6 p.

Research output: Contribution to specialist publicationArticle

Optic Neuritis
Optics
Multiple Sclerosis
Optic Nerve
Adrenal Cortex Hormones
13 Citations (Scopus)

Pharmacological Actions of Hydrogen Sulfide Donors on Sympathetic Neurotransmission in the Bovine Anterior Uvea, In Vitro

Salvi, A., Bankhele, P., Jamil, J. M., Kulkarni-Chitnis, M., Njie-Mbye, Y. F., Ohia, S. E. & Opere, C. A., May 1 2016, In : Neurochemical Research. 41, 5, p. 1020-1028 9 p.

Research output: Contribution to journalArticle

Uvea
Hydrogen Sulfide
Ciliary Body
Iris
Synaptic Transmission
2015
16 Citations (Scopus)

Inhibitory action of novel hydrogen sulfide donors on bovine isolated posterior ciliary arteries

Kulkarni-Chitnis, M., Njie-Mbye, Y. F., Mitchell, L., Robinson, J., Whiteman, M., Wood, M. E., Opere, C. A. & Ohia, S. E., May 1 2015, In : Experimental Eye Research. 134, p. 73-79 7 p.

Research output: Contribution to journalArticle

Ciliary Arteries
Hydrogen Sulfide
KATP Channels
Phenylephrine
Flurbiprofen

Preventive HIV vaccines: Progress and challenges

Bossou, A. R., Castillo, S., O’Brien, K. K., Opere, C. A. & Destache, C. J., Oct 16 2015, U.S. Pharmacist, 40, 10, p. 46-50 5 p.

Research output: Contribution to specialist publicationArticle

AIDS Vaccines
HIV Infections
Vaccines
HIV
Patient Compliance
2014
7 Citations (Scopus)

In vitro-controlled release delivery system for hydrogen sulfide donor

Ali, H., Opere, C. A. & Singh, S., 2014, In : AAPS PharmSciTech. 15, 4, p. 910-919 10 p.

Research output: Contribution to journalArticle

Hydrogen Sulfide
hydrogen sulfide
polymers
Polymers
sodium sulfide
9 Citations (Scopus)

Role of the Non-enzymatic Metabolite of Eicosapentaenoic Acid, 5-epi-5-F3t-Isoprostane in the Regulation of [3H]d-Aspartate Release in Isolated Bovine Retina

Jamil, J., Bankhele, P., Salvi, A., Mannix, J. E., Oger, C., Guy, A., Galano, J. M., Durand, T., Njie-Mbye, Y. F., Ohia, S. E. & Opere, C. A., Nov 25 2014, In : Neurochemical Research. 39, 12, p. 2360-2369 10 p.

Research output: Contribution to journalArticle

Isoprostanes
Eicosapentaenoic Acid
Metabolites
Aspartic Acid
Neurotransmitter Agents
2013
30 Citations (Scopus)

Pharmacological actions of the slow release hydrogen sulfide donor GYY4137 on phenylephrine-induced tone in isolated bovine ciliary artery

Chitnis, M. K., Njie-Mbye, Y. F., Opere, C. A., Wood, M. E., Whiteman, M. & Ohia, S. E., Nov 2013, In : Experimental Eye Research. 116, p. 350-354 5 p.

Research output: Contribution to journalArticle

Ciliary Arteries
Hydrogen Sulfide
Phenylephrine
Pharmacology
Cystathionine
2012
19 Citations (Scopus)

Mechanism of action of hydrogen sulfide on cyclic AMP formation in rat retinal pigment epithelial cells

Njie-Mbye, Y. F., Kulkarni, M., Opere, C. A. & Ohia, S. E., May 2012, In : Experimental Eye Research. 98, 1, p. 16-22 7 p.

Research output: Contribution to journalArticle

Hydrogen Sulfide
Retinal Pigments
Cyclic AMP
Epithelial Cells
Glyburide
9 Citations (Scopus)

Regulation of [ 3H]D-aspartate release by the 5-F 2t-isoprostane and its 5-epimer in isolated bovine retina

Jamil, J., Wright, A., Harrison, NC., Kegey, E., Flowers, A. F., Flyod, N. J., Kotera, C., Guy, A., Galano, J. M., Durand, T., Njie-Mbye, Y. F., Ohia, S. E. & Opere, C. A., Mar 2012, In : Neurochemical Research. 37, 3, p. 574-582 9 p.

Research output: Contribution to journalArticle

D-Aspartic Acid
Retina
Neurotransmitter Agents
Prostaglandins
Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide
2011
20 Citations (Scopus)

Endogenous production of hydrogen sulfide in isolated bovine eye

Kulkarni, M., Njie-Mbye, Y. F., Okpobiri, I., Zhao, M., Opere, C. A. & Ohia, S. E., Aug 2011, In : Neurochemical Research. 36, 8, p. 1540-1545 6 p.

Research output: Contribution to journalArticle

Hydrogen Sulfide
Methionine
Cysteine
Retina
Gasotransmitters
1 Citation (Scopus)

Understanding Diabetic Retinopathy

Opere, C. A., O'Brien, K. K. & Shea, J. L., Apr 2011, U.S. Pharmacist, 36, 4.

Research output: Contribution to specialist publicationArticle

Diabetic Retinopathy
2010
18 Citations (Scopus)

Effect of hydrogen sulfide on cyclic AMP production in isolated bovine and porcine neural retinae

Njie-Mbye, Y. F., Bongmba, O. Y. N., Onyema, C. C., Chitnis, A., Kulkarni, M., Opere, C. A., Leday, A. M. & Ohia, S. E., Mar 2010, In : Neurochemical Research. 35, 3, p. 487-494 8 p.

Research output: Contribution to journalArticle

Hydrogen Sulfide
Cyclic AMP
Retina
Swine
Colforsin
14 Citations (Scopus)

Role of hydrogen sulfide production in inhibitory action of L-cysteine on isolated porcine irides

Ohia, S. E., Opere, C. A., Monjok, E. M., Kouamou, G., Leday, A. M. & Njie-Mbye, Y. F., May 2010, In : Current Eye Research. 35, 5, p. 402-407 6 p.

Research output: Contribution to journalArticle

Hydrogen Sulfide
Iris
Cysteine
Swine
Cystathionine
2009
62 Citations (Scopus)

Effect of hydrogen sulfide on sympathetic neurotransmission and catecholamine levels in isolated porcine iris-ciliary body

Kulkarni, K. H., Monjok, E. M., Zeyssig, R., Kouamou, G., Bongmba, O. N., Opere, C. A., Njie, Y. F. & Ohia, S. E., Mar 2009, In : Neurochemical Research. 34, 3, p. 400-406 7 p.

Research output: Contribution to journalArticle

Hydrogen Sulfide
Ciliary Body
Iris
Synaptic Transmission
Catecholamines
17 Citations (Scopus)

Regulation of [3H] d-aspartate release from mammalian isolated retinae by hydrogen sulfide

Opere, C. A., Monjok, E. M., Kulkarni, K. H., Njie, Y. F. & Ohia, S. E., 2009, In : Neurochemical Research. 34, 11, p. 1962-1968 7 p.

Research output: Contribution to journalArticle

Hydrogen Sulfide
Aspartic Acid
Retina
Swine
Synaptic Transmission
8 Citations (Scopus)
Prostaglandins
Neurotransmitter Agents
Amino Acids
Glutamine
Glycine
2008
30 Citations (Scopus)

Inhibitory action of hydrogen sulfide on muscarinic receptor-induced contraction of isolated porcine irides

Monjok, E. M., Kulkarni, K. H., Kouamou, G., McKoy, M., Opere, C. A., Bongmba, O. N., Njie, Y. F. & Ohia, S. E., Dec 10 2008, In : Experimental Eye Research. 87, 6, p. 612-616 5 p.

Research output: Contribution to journalArticle

Hydrogen Sulfide
Muscarinic Receptors
Iris
Cystathionine
Swine
5 Citations (Scopus)

Prejunctional inhibitory effects of isoprostanes on dopaminergic neurotransmission in bovine retinae, in vitro

Liu, H., Zhao, M. & Opere, C. A., Jan 2008, In : Neurochemical Research. 33, 1, p. 37-42 6 p.

Research output: Contribution to journalArticle

Isoprostanes
Synaptic Transmission
Retina
Dopamine
Dinoprost
2 Citations (Scopus)
Amino Acids
Isoprostanes
Neurotransmitter Agents
Retina
Glutamic Acid
2006
20 Citations (Scopus)

Inhibition of potassium- and ischemia-evoked [3H] D-aspartate release from isolated bovine retina by cannabinoids

Opere, C. A., Zheng, W., Zhao, M., Lee, J., Kulkarni, K. & Ohia, S., Aug 1 2006, In : Current Eye Research. 31, 7-8, p. 645-653 9 p.

Research output: Contribution to journalArticle

D-Aspartic Acid
Cannabinoid Receptor CB1
Cannabinoids
Retina
Potassium
1 Citation (Scopus)

Regulation of norepinephrine release from isolated bovine irides by histamine

Kulkarni, K. H., Opere, C. A., LeDay, A. M., Shara, M. A. & Ohia, S. E., Jul 2006, In : Neurochemical Research. 31, 7, p. 891-897 7 p.

Research output: Contribution to journalArticle

Histamine Receptors
Histamine Agonists
Iris
Histamine
Methylhistamines
2005
19 Citations (Scopus)

Dual effect of isoprostanes on the release of [3H]D-aspartate from isolated bovine retinae: Role of arachidonic acid metabolites

Opere, C. A., Zheng, W. D., Huang, J., Adewale, A., Kruglet, M. & Ohia, S. E., Jan 2005, In : Neurochemical Research. 30, 1, p. 129-137 9 p.

Research output: Contribution to journalArticle

Isoprostanes
D-Aspartic Acid
Metabolites
Arachidonic Acid
8-epi-prostaglandin F2alpha
4 Citations (Scopus)

Ocular pharmacology of bicyclic hexahydroaporphines

Ohia, S. E., Zhan, G. L., LeDay, A. M., Opere, C. A., Kulkarni, K. H., Harris, L. C. & Roche, V. F., Mar 2005, In : Methods and Findings in Experimental and Clinical Pharmacology. 27, 2, p. 87-93 7 p.

Research output: Contribution to journalArticle

Intraocular Pressure
Pharmacology
Carbachol
Iris
Nitric Oxide
2004
11 Citations (Scopus)

Arachidonic acid metabolites and peroxide-induced inhibition of [ 3H]D-aspartate release from bovine isolated retinae

LeDay, A. M., Kulkarni, K. H., Opere, C. A. & Ohia, S. E., May 2004, In : Current Eye Research. 28, 5, p. 367-372 6 p.

Research output: Contribution to journalArticle

D-Aspartic Acid
Peroxides
Arachidonic Acid
Retina
Dinoprost
2 Citations (Scopus)

Effect of Peroxides on [3H]D-Aspartate Release from Bovine Isolated Retinae

LeDay, A. M., Awe, S. O., Kulkarni, K., Harris, L. C., Opere, C. A., Dash, A. K. & Ohia, S. E., Apr 2004, In : Neurochemical Research. 29, 4, p. 811-818 8 p.

Research output: Contribution to journalArticle

D-Aspartic Acid
Peroxides
Retina
Glutamic Acid
Vitreous Body
2003
4 Citations (Scopus)

Effect of Hydrogen Peroxide on Amino Acid Concentrations in Bovine Retina and Vitreous Humor, Ex Vivo

LeDay, A. M., Ganguly, S., Kulk̃arni, K. H., Dash, A., Opere, C. A. & Ohia, S. E., Nov 2003, In : Methods and Findings in Experimental and Clinical Pharmacology. 25, 9, p. 695-701 7 p.

Research output: Contribution to journalArticle

Vitreous Body
Glycine
Hydrogen Peroxide
Retina
Glutamic Acid
3 Citations (Scopus)

Glucose-Deprivation-Induced [3H]D-Aspartate Release from Isolated Bovine and Human Retinae

Ohia, S. E., Awe, S. O., Opere, C. A., LeDay, A. M., Harris, L. C., Kulkarni, K. & Sharif, N. A., Dec 2003, In : Journal of Ocular Pharmacology and Therapeutics. 19, 6, p. 599-609 11 p.

Research output: Contribution to journalArticle

D-Aspartic Acid
Retina
Glucose
Excitatory Amino Acid Agonists
Nitrendipine
2002
15 Citations (Scopus)

Pharmacology of serotonin receptors modulating electrically-induced [3H]-norepinephrine release from isolated mammalian iris-ciliary bodies

Harris, L. C., Awe, S. O., Opere, C. A., Leday, A. M., Ohia, S. E. & Sharif, N. A., Aug 2002, In : Journal of Ocular Pharmacology and Therapeutics. 18, 4, p. 339-348 10 p.

Research output: Contribution to journalArticle

Ciliary Body
Serotonin Receptors
Iris
Serotonin
Norepinephrine
83 Citations (Scopus)

Safety and mechanism of appetite suppression by a novel hydroxycitric acid extract (HCA-SX)

Ohia, S. E., Opere, C. A., LeDay, A. M., Bagchi, M., Bagchi, D. & Stohs, S. J., Sep 2002, In : Molecular and Cellular Biochemistry. 238, 1-2, p. 89-103 15 p.

Research output: Contribution to journalArticle

Appetite
Serotonin
Safety
Rats
Clomipramine
2001
18 Citations (Scopus)

[3H]-Serotonin release from bovine iris-ciliary body: Pharmacology of prejunctional serotonin (5-HT7) autoreceptors

Harris, L. C., Awe, S. O., Opere, C. A., LeDay, A. M., Ohia, S. E. & Sharif, N. A., 2001, In : Experimental Eye Research. 73, 1, p. 59-67 9 p.

Research output: Contribution to journalArticle

Autoreceptors
Ciliary Body
Iris
Serotonin
Pharmacology
4 Citations (Scopus)

Assessment of the intraocular pressure-lowering activity of bicyclic derivatives of 1-substituted benzyloctahydroisoquinoline

Saha, S. L., Igbo, I. N., Opere, C. A., Zhan, G. L., Tanimaya, J., Ohia, S. E. & Roche, V. F., 2001, In : Journal of Ocular Pharmacology and Therapeutics. 17, 5, p. 413-420 8 p.

Research output: Contribution to journalArticle

Intraocular Pressure
Rabbits
Topical Administration
Ocular Hypertension
Amines
40 Citations (Scopus)

Effect of hydroxycitric acid on serotonin release from isolated rat brain cortex

Ohia, S. E., Awe, S. O., LeDay, A. M., Opere, C. A. & Bagchi, D., 2001, In : Research Communications in Molecular Pathology and Pharmacology. 109, 3-4, p. 210-216 7 p.

Research output: Contribution to journalArticle

Serotonin
Brain
Garcinia cambogia
Tritium
Fruit
14 Citations (Scopus)

Hypoxia-induced [3H]D-aspartate release from isolated bovine retina: Modulation by calcium-channel blockers and glutamatergic agonists and antagonists

Ohia, S. E., Awe, S. O., Opere, C. A., LeDay, A. M., Harris, L. C. & Sharif, N. A., 2001, In : Current Eye Research. 23, 5, p. 386-392 7 p.

Research output: Contribution to journalArticle

D-Aspartic Acid
Calcium Channel Blockers
Retina
Excitatory Amino Acid Agonists
Excitatory Amino Acid Antagonists
16 Citations (Scopus)

Potentiation of sympathetic neurotransmission in bovine isolated irides by isoprostanes

Opere, C. A., Olubusayo Awe, S., Harris, L. C., LeDay, A. M. & Ohia, S. E., 2001, In : Free Radical Research. 35, 3, p. 257-264 8 p.

Research output: Contribution to journalArticle

Isoprostanes
Iris
Synaptic Transmission
Norepinephrine
Thromboxane Receptors
2000
7 Citations (Scopus)

Effect of inhibition of cyclooxygenase on pre- and postjunctional actions of peroxides in the iris-ciliary body

Graham, J., Awe, S. O., LeDay, A. M., Rice, J. C., Ramos, G., Harris, L. C., Opere, C. A. & Ohia, S. E., 2000, In : Neurochemical Research. 25, 4, p. 519-525 7 p.

Research output: Contribution to journalArticle

Flurbiprofen
Ciliary Body
Peroxides
Iris
Prostaglandin-Endoperoxide Synthases
18 Citations (Scopus)

Effect of isoprostanes on sympathetic neurotransmission in the human isolated iris-ciliary body

Awe, S. O., Opere, C. A., Harris, L. C., Uketui, A. J. & Ohia, S. E., 2000, In : Neurochemical Research. 25, 4, p. 491-496 6 p.

Research output: Contribution to journalArticle

Isoprostanes
Ciliary Body
Iris
Synaptic Transmission
Norepinephrine
16 Citations (Scopus)

Human, bovine, and rabbit retinal glutamate-induced [3H]D-aspartate release: Role in excitotoxicity

Ohia, S. E., Opere, C. A., Olubusayo Awe, S., Adams, L. & Sharif, N. A., 2000, In : Neurochemical Research. 25, 6, p. 853-860 8 p.

Research output: Contribution to journalArticle

D-Aspartic Acid
Glutamic Acid
Rabbits
Retina
Polyamines
5 Citations (Scopus)

Role of catalase in pre- and postjunctional responses of mammalian irides to hydrogen peroxide

Matutte, B., Awe, S. O., Ameh, F. A., Leday, A. M., Rice, J. C., Opere, C. A. & Ohia, S. E., 2000, In : Journal of Ocular Pharmacology and Therapeutics. 16, 5, p. 429-438 10 p.

Research output: Contribution to journalArticle

Iris
Catalase
Hydrogen Peroxide
Triazoles
Norepinephrine
1998
16 Citations (Scopus)

Effect of prostaglandins on cyclic AMP production in cultured human ciliary muscle cells

Zhan, G. L., Camras, C. B., Opere, C. A., Tang, L. & Ohia, S. E., Feb 1998, In : Journal of Ocular Pharmacology and Therapeutics. 14, 1, p. 45-55 11 p.

Research output: Contribution to journalArticle

Cyclic AMP
Muscle Cells
Prostaglandins
Prostaglandins E
Prostaglandins D