• 2076 Citations
  • 25 h-Index
1985 …2018
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  • 4 Similar Profiles
Nanoparticles Medicine & Life Sciences
Rilpivirine Medicine & Life Sciences
Pharmacokinetics Medicine & Life Sciences
HIV-1 Medicine & Life Sciences
Tenofovir Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
HIV Medicine & Life Sciences
Therapeutics Medicine & Life Sciences

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Projects 2008 2018

Nanoparticles
HIV
Rilpivirine
Tenofovir
Drug Combinations

Once Monthly Antiretroviral Nanoparticles for HIV-1 Treatment

Destache, C. J.

National Institutes of Health

6/15/115/31/13

Project: Research projectHigh Priority, Short Term Project Award

Nanoparticles
HIV-1
Therapeutics
Macaca
Macaca nemestrina

Pharmacology of Antiretroviral Nanoparticle Micelles

Destache, C. J.

National Institutes of Health

6/1/085/31/11

Project: Research projectAcademic Research Enhancement Awards (AREA)

Micelles
Nanoparticles
HIV-1
Pharmacology
efavirenz

Research Output 1985 2018

1 Citations

Discovery of a non-nucleoside RNA polymerase inhibitor for blocking Zika virus replication through in silico screening

Pattnaik, A., Palermo, N., Sahoo, B. R., Yuan, Z., Hu, D., Annamalai, A. S., Vu, H. L. X., Correas, I., Prathipati, P. K., Destache, C. J., Li, Q., Osorio, F. A., Pattnaik, A. K. & Xiang, S. H. Mar 1 2018 In : Antiviral Research. 151, p. 78-86 9 p.

Research output: Contribution to journalArticle

DNA-Directed RNA Polymerases
Virus Replication
Computer Simulation
RNA Replicase
Catalytic Domain

LC-MS/MS method for the simultaneous determination of tenofovir, emtricitabine, elvitegravir and rilpivirine in dried blood spots

Prathipati, P. K., Mandal, S. & Destache, C. J. Jan 1 2018 (Accepted/In press) In : Biomedical Chromatography.

Research output: Contribution to journalArticle

Rilpivirine
Tenofovir
formic acid
Carry logic
Hematocrit
4 Citations

An enhanced emtricitabine-loaded long-acting nanoformulation for prevention or treatment of HIV infection

Mandal, S., Belshan, M., Holec, A., Zhou, Y. & Destache, C. J. Jan 1 2017 In : Antimicrobial Agents and Chemotherapy. 61, 1, e01475-16

Research output: Contribution to journalArticle

HIV Infections
Blood Cells
Nucleosides
Inhibitory Concentration 50
HIV-1

Cellulose acetate phthalate and antiretroviral nanoparticle fabrications for HIV pre-exposure prophylaxis

Mandal, S., Khandalavala, K., Pham, R., Bruck, P., Varghese, M., Kochvar, A., Monaco, A., Prathipati, P. K., Destache, C. & Shibata, A. Sep 7 2017 In : Polymers. 9, 9, 423

Research output: Contribution to journalArticle

Cellulose
Nanoparticles
Fabrication
Gels
Polydispersity

Evaluation of Staphylococcus aureus Bacteremia: Academic and Community-Based Management Within the Same Health System

Ased, S., Rayes, H., Dhami, J., Amosson, N., Fordjour, A., Macaraeg, J., Vivekanandan, R., Wilson, J., Cabri, A., Davids, M., Anthone, J., Cavalieri, S. & Destache, C. J. Jun 1 2017 In : Infection Control and Hospital Epidemiology. 38, 6, p. 740-742 3 p.

Research output: Contribution to journalArticle

Community Hospital
Bacteremia
Staphylococcus aureus
Health
Communicable Diseases