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Christopher J. Destache, PharmD, FCCP

Professor

  • 2225 Citations
  • 26 h-Index
1985 …2019
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Projects 2008 2018

Long-acting antiretroviral nanoparticles for HIV prophylaxis

Destache, C. J.

National Institutes of Health

2/4/15 → 1/31/18

Project: Research project

Nanoparticles
HIV
Rilpivirine
Tenofovir
Drug Combinations

Once Monthly Antiretroviral Nanoparticles for HIV-1 Treatment

Destache, C. J.

National Institutes of Health

6/15/11 → 5/31/13

Project: Research project

Nanoparticles
HIV-1
Therapeutics
Macaca
Macaca nemestrina

Pharmacology of Antiretroviral Nanoparticle Micelles

Destache, C. J.

National Institutes of Health

6/1/08 → 5/31/11

Project: Research project

Micelles
Nanoparticles
HIV-1
Pharmacology
efavirenz

Research Output 1985 2019

A review of CCR5 antibodies against HIV: current and future aspects

Prathipati, P. K., Mandal, S. & Destache, C. J., Feb 1 2019, In : Therapeutic Delivery. 10, 2, p. 107-112 6 p.

Research output: Contribution to journal › Article

HIV Antibodies
HIV
Viruses
Antibodies
Virus Diseases

Ceftaroline fosamil for the treatment of Gram-positive endocarditis: CAPTURE study experience

Destache, C. J., Guervil, D. J. & Kaye, K. S., Jan 1 2019, In : International Journal of Antimicrobial Agents.

Research output: Contribution to journal › Article

Open Access
Endocarditis
Therapeutics
Methicillin-Resistant Staphylococcus aureus
Methicillin
PPI-0903

Indole-2-carboxamides are active against mycobacterium abscessus in a mouse model of acute infection

Pandya, A. N., Prathipati, P. K., Hegde, P., Li, W., Graham, K. F., Mandal, S., Drescher, K. M., Destache, C. J., Ordway, D., Jackson, M. & Northa, E. J., Mar 1 2019, In : Antimicrobial Agents and Chemotherapy. e02245-18.

Research output: Contribution to journal › Article

Nontuberculous Mycobacteria
Mycobacterium
Lung
Bacterial Load
Infection

Nanoencapsulation introduces long-acting phenomenon to tenofovir alafenamide and emtricitabine drug combination: A comparative pre-exposure prophylaxis efficacy study against HIV-1 vaginal transmission

Mandal, S., Kang, G., Prathipati, P. K., Zhou, Y., Fan, W., Li, Q. & Destache, C. J., Jan 28 2019, In : Journal of Controlled Release. 294, p. 216-225 10 p.

Research output: Contribution to journal › Article

Drug Combinations
HIV-1
Nanoparticles
GS-7340
Pre-Exposure Prophylaxis
1 Citation (Scopus)

Development and validation of LC–MS/MS method for quantification of bictegravir in human plasma and its application to an intracellular uptake study

Prathipati, P. K., Mandal, S. & Destache, C. J., Jan 1 2018, (Accepted/In press) In : Biomedical Chromatography. e4379.

Research output: Contribution to journal › Article

Plasma (human)
formic acid
Mass spectrometers
Mass spectrometry
United States Food and Drug Administration