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Personal profile

External positions

Duke University

National Cancer Institute

National Institute for Environmental Health Sciences

North Carolina State University

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Skin Medicine & Life Sciences
Epidermal Growth Factor Receptor Medicine & Life Sciences
Papilloma Medicine & Life Sciences
Carcinogenesis Medicine & Life Sciences
Keratinocytes Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Skin Neoplasms Medicine & Life Sciences
Transgenes Medicine & Life Sciences

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Projects 2001 2014

Papilloma
Hair Follicle
Skin
Transgenic Mice
Carcinogenesis

Mechanisms of UV-induced skin carcinogenesis

Hansen, L. A.

National Institutes of Health

12/1/0711/30/14

Project: Research projectResearch Project

Carcinogenesis
Skin Neoplasms
Skin
DNA Damage
Cell Cycle Checkpoints

Nebraska Center for Cellular Signaling

Hansen, L. A. & Tu, Y.

National Institutes of Health

9/19/036/30/13

Project: Research projectExploratory Grants

funding
school
infrastructure
cancer
dentistry

THE ROLE OF EGFR IN UV-INDUCED SKIN CARCINOGENESIS

Hansen, L. A.

National Institutes of Health

1/23/0112/31/04

Project: Research projectCareer Transition Award

Epidermal Growth Factor Receptor
Carcinogenesis
Radiation
Skin
Keratinocytes

Research Output 1988 2018

2 Citations

The curcumin analog HO-3867 selectively kills cancer cells by converting mutant p53 protein to transcriptionally active wildtype p53

Madan, E., Parker, T. M., Bauer, M. R., Dhiman, A., Pelham, C. J., Nagane, M., Lakshmi Kuppusamy, M., Holmes, M., Holmes, T. R., Shaik, K., Shee, K., Kiparoidze, S., Smith, S. D., Park, Y. S. A., Gomm, J. J., Jones, L. J., Tomás, A. R., Cunha, A. C., Selvendiran, K., Hansen, L. A. & 4 othersFersht, A. R., Hideg, K., Gogna, R. & Kuppusamy, P., Jan 1 2018, In : Journal of Biological Chemistry. 293, 12, p. 4262-4276 15 p.

Research output: Contribution to journalArticle

Curcumin
Mutant Proteins
Cells
Pharmaceutical Preparations
Tumor Suppressor Proteins
2 Citations

Accumulation of cytoplasmic CDC25A in cutaneous squamous cell carcinoma leads to a dependency on CDC25A for cancer cell survival and tumor growth

Al-Matouq, J., Holmes, T., Hammiller, B., Tran, N., Holmes, M., Freeman, S. C. & Hansen, L. A., Dec 1 2017, In : Cancer Letters. 410, p. 41-49 9 p.

Research output: Contribution to journalArticle

Skin Neoplasms
Squamous Cell Carcinoma
Cell Survival
Skin
Growth

Delivery of antioxidant enzymes for prevention of ultraviolet irradiation-induced epidermal damage

Hammiller, B., Karuturi, B. V. K., Miller, C., Holmes, M., Labhasetwar, V., Madsen, G. & Hansen, L. A., 2017, (Accepted/In press) In : Journal of Dermatological Science.

Research output: Contribution to journalArticle

Antioxidants
Irradiation
Enzymes
3 Citations

The epidermal growth factor receptor decreases Stathmin 1 and triggers catagen entry in the mouse

Bichsel, K. J., Hammiller, B., Trempus, C. S., Li, Y. & Hansen, L. A., Apr 1 2016, In : Experimental Dermatology. 25, 4, p. 275-281 7 p.

Research output: Contribution to journalArticle

Stathmin
Epidermal Growth Factor Receptor
Hair Follicle
Skin
Keratinocytes

A method for the immortalization of newborn mouse skin keratinocytes

Hammiller, B. O., El-Abaseri, T. B., Dlugosz, A. A. & Hansen, L. A., 2015, In : Frontiers in Oncology. 5, JUL, 177.

Research output: Contribution to journalArticle

Keratinocytes
Skin
Fibroblast Growth Factor 7
Cell Line
Karyotype