• 1163 Citations
  • 16 h-Index
1988 …2020

Research output per year

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Research Output

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Article
2020
2019

Aminoglycosides rapidly inhibit NAD(P)H metabolism increasing reactive oxygen species and cochlear cell demise

Desa, D. E., Nichols, M. G. & Smith, H. J., May 1 2019, In : Journal of Biomedical Optics. 24, 5, 051403.

Research output: Contribution to journalArticle

6 Scopus citations
1 Scopus citations
2016

Chemotherapy impedes in vitro microcirculation and promotes migration of leukemic cells with impact on metastasis

Prathivadhi-Bhayankaram, S. V., Ning, J., Mimlitz, M., Taylor, C., Gross, E. M., Nichols, M. G., Guck, J. & Ekpenyong, A., Oct 28 2016, In : Biochemical and Biophysical Research Communications. 479, 4, p. 841-846 6 p.

Research output: Contribution to journalArticle

3 Scopus citations
2015

Gentamicin differentially alters cellular metabolism of cochlear hair cells as revealed by NAD(P)H fluorescence lifetime imaging

Zholudeva, L. V., Ward, K. G., Nichols, M. G. & Smith, H. J., May 1 2015, In : Journal of Biomedical Optics. 20, 5, 051032.

Research output: Contribution to journalArticle

8 Scopus citations
2013

The conserved tetrameric subunit stoichiometry of Slc26 proteins

Hallworth, R., Stark, K., Zholudeva, L., Currall, B. B. & Nichols, M. G., Aug 1 2013, In : Microscopy and Microanalysis. 19, 4, p. 799-807 9 p.

Research output: Contribution to journalArticle

9 Scopus citations
2012

Gentamicin rapidly inhibits mitochondrial metabolism in high-frequency cochlear outer hair cells

Jensen-Smith, H. C., Hallworth, R. & Nichols, M. G., Jun 8 2012, In : PloS one. 7, 6, e38471.

Research output: Contribution to journalArticle

34 Scopus citations

Metabolic imaging using two-photon excited nadh intensity and fluorescence lifetime imaging

Vergen, J., Hecht, C., Zholudeva, L. V., Marquardt, M. M., Hallworth, R. & Nichols, M. G., Aug 1 2012, In : Microscopy and Microanalysis. 18, 4, p. 761-770 10 p.

Research output: Contribution to journalArticle

35 Scopus citations

Prestin in HEK cells is an obligate tetramer

Hallworth, R. & Nichols, M. G., Jan 1 2012, In : Journal of Neurophysiology. 107, 1, p. 5-11 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

The single molecule imaging approach to membrane protein stoichiometry

Hallworth, R. & Nichols, M. G., Aug 1 2012, In : Microscopy and Microanalysis. 18, 4, p. 771-780 10 p.

Research output: Contribution to journalArticle

10 Scopus citations
2010

Photo- and bio-physical characterization of novel violet and near-infrared lipophilic fluorophores for neuronal tracing

Tonniges, J., Hansen, M., Duncan, J., Bassett, M. J., Fritzsch, B., Gray, B. D., Easwaran, A. & Nichols, M. G., Aug 2010, In : Journal of Microscopy. 239, 2, p. 117-134 18 p.

Research output: Contribution to journalArticle

16 Scopus citations
2009

Determination of cell elasticity through hybrid ray optics and continuum mechanics modeling of cell deformation in the optical stretcher

Ekpenyong, A. E., Posey, C. L., Chaput, J. L., Burkart, A. K., Marquardt, M. M., Smith, T. J. & Nichols, M. G., Nov 10 2009, In : Applied Optics. 48, 32, p. 6344-6354 11 p.

Research output: Contribution to journalArticle

19 Scopus citations

Metabolic imaging of the organ of corti - A window on cochlea bioenergetics

Tiede, L. A., Steyger, P. S., Nichols, M. G. & Hallworth, R., Jun 24 2009, In : Brain Research. 1277, p. 37-41 5 p.

Research output: Contribution to journalArticle

20 Scopus citations
2007

Determination of hair cell metabolic state in isolated cochlear preparations by two-photon microscopy

Tiede, L. M., Rocha-Sanchez, S. M., Hallworth, R., Nichols, M. G. & Beisel, K., Mar 1 2007, In : Journal of Biomedical Optics. 12, 2, 021004.

Research output: Contribution to journalArticle

29 Scopus citations
2006

Near-infrared laser illumination transforms the fluorescence absorbing X-Gal reaction product BCI into a transparent, yet brightly fluorescent substance

Matei, V. A., Feng, F., Pauley, S., Beisel, K. W., Nichols, M. G. & Fritzsch, B., Jun 15 2006, In : Brain Research Bulletin. 70, 1, p. 33-43 11 p.

Research output: Contribution to journalArticle

17 Scopus citations
25 Scopus citations
2005

A comparison of the sensitivity of photodamage assays in rat basophilic leukemia cells

Barth, E. E., Hallworth, R. & Nichols, M. G., May 1 2005, In : Photochemistry and Photobiology. 81, 3, p. 556-562 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Reduction in DNA synthesis during two-photon microscopy of intrinsic reduced nicotinamide adenine dinucleotide fluorescence

Nichols, M. G., Barth, E. E. & Nichols, J. A., Mar 1 2005, In : Photochemistry and Photobiology. 81, 2, p. 259-269 11 p.

Research output: Contribution to journalArticle

15 Scopus citations
2001

Retrofitted confocal laser scanner for a commercial inverted fluorescence microscope

Bigelow, C. E., Harkrider, C. J., Conover, D. L., Foster, T. H., Georgakoudi, I., Mitra, S., Nichols, M. G. & Rajadhyaksha, M., Aug 1 2001, In : Review of Scientific Instruments. 72, 8, p. 3407-3410 4 p.

Research output: Contribution to journalArticle

13 Scopus citations
2000

Effect of molecular structure on the performance of triarylmethane dyes as therapeutic agents for photochemical purging of autologous bone marrow grafts from residual tumor cells

Indig, G. L., Anderson, G. S., Nichols, M. G., Bartlett, J. A., Mellon, W. S. & Sieber, F., Jan 2000, In : Journal of Pharmaceutical Sciences. 89, 1, p. 88-99 12 p.

Research output: Contribution to journalArticle

69 Scopus citations
1998

Localization of luminescent inhomogeneities in turbid media with spatially resolved measurements of cw diffuse luminescence emittance

Hull, E. L., Nichols, M. G. & Foster, T. H., May 1 1998, In : Applied Optics. 37, 13, p. 2755-2765 11 p.

Research output: Contribution to journalArticle

58 Scopus citations

Quantitative broadband near-infrared spectroscopy of tissue-simulating phantoms containing erythrocytes

Hull, E. L., Nichols, M. G. & Foster, T. H., Nov 1 1998, In : Physics in Medicine and Biology. 43, 11, p. 3381-3404 24 p.

Research output: Contribution to journalArticle

85 Scopus citations
1997

Design and testing of a white-light, steady-state diffuse reflectance spectrometer for determination of optical properties of highly scattering systems

Nichols, M. G., Hull, E. L. & Foster, T. H., Jan 1 1997, In : Applied Optics. 36, 1, p. 93-104 12 p.

Research output: Contribution to journalArticle

165 Scopus citations

The Mechanism of Photofrin® Photobleaching and Its Consequences for Photodynamic Dosimetry

Georgakoudi, I., Nichols, M. G. & Foster, T. H., Jan 1997, In : Photochemistry and Photobiology. 65, 1, p. 135-144 10 p.

Research output: Contribution to journalArticle

202 Scopus citations
1994

Oxygen diffusion and reaction kinetics in the photodynamic therapy of multicell tumour spheroids

Nichols, M. G. & Foster, T. H., Dec 1 1994, In : Physics in Medicine and Biology. 39, 12, p. 2161-2181 21 p., 003.

Research output: Contribution to journalArticle

102 Scopus citations
1993

Fluence Rate Effects in Photodynamic Therapy of Multicell Tumor Spheroids

Foster, T. H., Hartley, D. F., Nichols, M. G. & Hilf, R., Mar 1993, In : Cancer Research. 53, 6, p. 1249-1254 6 p.

Research output: Contribution to journalArticle

153 Scopus citations