• 442 Citations
  • 14 h-Index
1984 …2014
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Personal profile

External positions

Emory University

Max Planck Institute for Experimental Medicine

Salk Institute for Biological Studies

Fingerprint Dive into the research topics where Robert Mackin is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Proinsulin Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Proglucagon Medicine & Life Sciences
Secretory Vesicles Medicine & Life Sciences
Purification Chemical Compounds
Proprotein Convertase 2 Medicine & Life Sciences
Carboxypeptidase B Medicine & Life Sciences
Peptides Medicine & Life Sciences

Research Output 1984 2014

  • 442 Citations
  • 14 h-Index
  • 26 Article
  • 1 Review article
Inclusion Bodies
divinyl benzene
2 Citations (Scopus)

Epidemiology and clinical diagnosis: Alzheimer disease

Mackin, R., Oct 2013, In : PET Clinics. 8, 4, p. 391-405 15 p.

Research output: Contribution to journalArticle

Alzheimer Disease
28 Citations (Scopus)

An Achilles' heel in an amyloidogenic protein and its repair: Insulin fibrillation and therapeutic design

Yang, Y., Petkova, A., Huang, K., Xu, B., Hua, Q. X., Ye, I. J., Chu, Y. C., Hu, S. Q., Phillips, N. B., Whittaker, J., Ismail-Beigi, F., Mackin, R., Katsoyannis, P. G., Tycko, R. & Weiss, M. A., Apr 2 2010, In : Journal of Biological Chemistry. 285, 14, p. 10806-10821 16 p.

Research output: Contribution to journalArticle

Amyloidogenic Proteins
Chemical shift
Substitution reactions
33 Citations (Scopus)

Solution structure of proinsulin: Connecting domain flexibility and prohormone processing

Yang, Y., Hua, Q. X., Liu, J., Shimizu, E. H., Choquette, M. H., Mackin, R. & Weiss, M. A., Mar 12 2010, In : Journal of Biological Chemistry. 285, 11, p. 7847-7851 5 p.

Research output: Contribution to journalArticle

Medical problems
Diabetes Mellitus
18 Citations (Scopus)

Crystal structure of a "nonfoldable" insulin. Impaired folding efficiency despite native activity

Liu, M., Wan, Z. I., Chu, Y. C., Aladdin, H., Klaproth, B., Choquette, M., Hua, Q. X., Mackin, R., Rao, J. S., De Meyts, P., Katsoyannis, P. G., Arvan, P. & Weiss, M. A., Dec 11 2009, In : Journal of Biological Chemistry. 284, 50, p. 35259-35272 14 p.

Research output: Contribution to journalArticle

Crystal structure
Substitution reactions