• 3910 Citations
  • 37 h-Index
19982020
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Personal profile

External positions

Mayo Clinic

Shanxi Medical University

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  • 6 Similar Profiles
Cryptosporidium parvum Medicine & Life Sciences
Epithelial Cells Medicine & Life Sciences
MicroRNAs Medicine & Life Sciences
Cryptosporidium Medicine & Life Sciences
Infection Medicine & Life Sciences
Parasites Medicine & Life Sciences
Cryptosporidiosis Medicine & Life Sciences
Long Noncoding RNA Medicine & Life Sciences

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Projects 2006 2020

Molecular Basis of Intestinal Cryptosporidiosis

Chen, X.

National Institutes of Health

2/4/151/31/20

Project: Research projectResearch Project

Cryptosporidiosis
Untranslated RNA
Parasites
Cryptosporidium
Infection

Epithelial exosomes and TLR-mediated mucosal defense

Chen, X.

National Institutes of Health

7/1/116/30/16

Project: Research projectResearch Project--Cooperative Agreements

Exosomes
Toll-Like Receptors
MicroRNAs
Epithelial Cells
Mucosal Immunity

MicroRNAs in Epithelial Innate Immunity to C. parvum

Chen, X.

National Institutes of Health

7/1/066/30/11

Project: Research projectResearch Project

Cryptosporidium parvum
MicroRNAs
Innate Immunity
Toll-Like Receptors
NF-kappa B

Research Output 1998 2018

Astrocyte EV-Induced lincRNA-Cox2 Regulates Microglial Phagocytosis: Implications for Morphine-Mediated Neurodegeneration

Hu, G., Liao, K., Niu, F., Yang, L., Dallon, B. W., Callen, S., Tian, C., Shu, J., Cui, J., Sun, Z., Lyubchenko, Y. L., Ka, M., Chen, X-M. & Buch, S., Dec 7 2018, In : Molecular Therapy - Nucleic Acids. 13, p. 450-463 14 p.

Research output: Contribution to journalArticle

Long Noncoding RNA
Phagocytosis
Astrocytes
Morphine
Microglia

Attenuation of intestinal epithelial cell migration during cryptosporidium parvum infection involves parasite Cdg7-FLc-1030 RNA-Mediated induction and release of dickkopf-1

Ming, Z., Wang, Y., Gong, A. Y., Zhang, X. T., Li, M., Chen, T., Mathy, N. W., Strauss-Soukup, J. K. & Chen, X-M., Sep 8 2018, In : Journal of Infectious Diseases. 218, 8, p. 1336-1347 12 p.

Research output: Contribution to journalArticle

Cryptosporidium parvum
Parasitic Diseases
Cell Movement
Epithelial Cells
RNA

Creatinine downregulates TNF-α in macrophage and T cell lines

Riesberg, L. A., McDonald, T. L., Wang, Y., Chen, X-M., Holzmer, S. W., Tracy, S. M. & Drescher, K. M., Oct 1 2018, In : Cytokine. 110, p. 29-38 10 p.

Research output: Contribution to journalArticle

T-cells
Macrophages
Creatinine
Down-Regulation
Tumor Necrosis Factor-alpha
5 Citations

Involvement of cryptosporidium parvum Cdg7-FLc-1000 RNA in the attenuation of intestinal epithelial cell migration via trans-suppression of host cell SMPD3

Ming, Z., Gong, A. Y., Wang, Y., Zhang, X. T., Li, M., Mathy, N. W., Strauss-Soukup, J. K. & Chen, X-M., Jan 1 2018, In : Journal of Infectious Diseases. 217, 1, p. 122-133 12 p.

Research output: Contribution to journalArticle

Cryptosporidium parvum
Cell Movement
Epithelial Cells
RNA
Methylation
1 Citations

Nuclear delivery of parasite Cdg2_FLc_0220 RNA transcript to epithelial cells during Cryptosporidium parvum infection modulates host gene transcription

Zhao, G. H., Gong, A. Y., Wang, Y., Zhang, X. T., Li, M., Mathy, N. W. & Chen, X-M., Feb 15 2018, In : Veterinary Parasitology. 251, p. 27-33 7 p.

Research output: Contribution to journalArticle

Cryptosporidium parvum
messenger RNA
Parasites
epithelial cells
transcription (genetics)