• 3706 Citations
  • 37 h-Index
19982020
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Personal profile

External positions

Mayo Clinic

Shanxi Medical University

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  • 3 Similar Profiles
Cryptosporidium parvum Medicine & Life Sciences
Epithelial Cells Medicine & Life Sciences
MicroRNAs Medicine & Life Sciences
Cryptosporidium Medicine & Life Sciences
Cryptosporidiosis Medicine & Life Sciences
Infection Medicine & Life Sciences
Parasites Medicine & Life Sciences
Genes Medicine & Life Sciences

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Projects 2006 2020

Molecular Basis of Intestinal Cryptosporidiosis

Chen, X.

National Institutes of Health

2/4/151/31/20

Project: Research projectResearch Project

Cryptosporidiosis
Untranslated RNA
Parasites
Cryptosporidium
Infection

Epithelial exosomes and TLR-mediated mucosal defense

Chen, X.

National Institutes of Health

7/1/116/30/16

Project: Research projectResearch Project--Cooperative Agreements

Exosomes
Toll-Like Receptors
MicroRNAs
Epithelial Cells
Mucosal Immunity

MicroRNAs in Epithelial Innate Immunity to C. parvum

Chen, X.

National Institutes of Health

7/1/066/30/11

Project: Research projectResearch Project

Cryptosporidium parvum
MicroRNAs
Innate Immunity
Toll-Like Receptors
NF-kappa B

Research Output 1998 2018

Creatinine downregulates TNF-α in macrophage and T cell lines

Riesberg, L. A., McDonald, T. L., Wang, Y., Chen, X. M., Holzmer, S. W., Tracy, S. M. & Drescher, K. M. Oct 1 2018 In : Cytokine. 110, p. 29-38 10 p.

Research output: Contribution to journalArticle

Cerium
Creatinine
Down-Regulation
Tumor Necrosis Factor-alpha
Macrophages
3 Citations

Involvement of cryptosporidium parvum Cdg7-FLc-1000 RNA in the attenuation of intestinal epithelial cell migration via trans-suppression of host cell SMPD3

Ming, Z., Gong, A. Y., Wang, Y., Zhang, X. T., Li, M., Mathy, N. W., Strauss-Soukup, J. K. & Chen, X. M. Jan 1 2018 In : Journal of Infectious Diseases. 217, 1, p. 122-133 12 p.

Research output: Contribution to journalArticle

Cryptosporidium parvum
Cryptosporidiosis
Cryptosporidium
Parasitic Diseases
Intestinal Mucosa

Nuclear delivery of parasite Cdg2_FLc_0220 RNA transcript to epithelial cells during Cryptosporidium parvum infection modulates host gene transcription

Zhao, G. H., Gong, A. Y., Wang, Y., Zhang, X. T., Li, M., Mathy, N. W. & Chen, X. M. Feb 15 2018 In : Veterinary Parasitology. 251, p. 27-33 7 p.

Research output: Contribution to journalArticle

Cryptosporidium parvum
Cryptosporidium
Intestinal Mucosa
messenger RNA
intestinal mucosa

Trans-suppression of defense DEFB1 gene in intestinal epithelial cells following Cryptosporidium parvum infection is associated with host delivery of parasite Cdg7_FLc_1000 RNA

Ming, Z., Gong, A. Y., Wang, Y., Zhang, X. T., Li, M., Dolata, C. E. & Chen, X. M. Jan 26 2018 (Accepted/In press) In : Parasitology Research. p. 1-10 10 p.

Research output: Contribution to journalArticle

Cryptosporidium parvum
Cryptosporidium
Intestinal Mucosa
intestinal mucosa
Parasites

Trans-suppression of host CDH3 and LOXL4 genes during Cryptosporidium parvum infection involves nuclear delivery of parasite Cdg7_FLc_1000 RNA

Ming, Z., Gong, A. Y., Wang, Y., Zhang, X. T., Li, M., Li, Y., Pang, J., Dong, S., Strauss-Soukup, J. K. & Chen, X. M. Jan 1 2018 (Accepted/In press) In : International Journal for Parasitology.

Research output: Contribution to journalArticle

Protein-Lysine 6-Oxidase
Cryptosporidium parvum
Cadherins
Parasites
RNA