LincRNAs in Mucosal Defense to AIDS Opportunistic Pathogen Cryptosporidium

  • Chen, Xian-Ming (CoPI)
  • Chen, Xian-ming X (PI)

Project: Research project

Project Details


Health Relevance Cryptosporidial infection remains significant in AIDS patients and young children. The proposed research will study the role of epithelial lincRNAs in IFN-γ-mediated GI mucosal immune responses. The overall goal is to elucidate the molecular mechanisms by which epithelial cell-specific lincRNAs coordinate mucosal anti- Cryptosporidium defense and provide a basis for the identification of novel targets for therapeutic intervention.
Effective start/end date11/6/1710/31/22


  • National Institute of Allergy and Infectious Diseases: $363,750.00
  • National Institute of Allergy and Infectious Diseases: $363,750.00


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