13. Synthesis and tritium labelling of 6β-amino-4,5α-epoxyraorphinans and their 14-hydroxy derivatives as potential affinity labelling probes with μ opioid agonist activity

Ferenc Ötvös, Géza Tóth, Sándor Lovas, Csaba Simon, Sándor Hosztafi

Research output: Contribution to journalArticle

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Abstract

The synthesis of 6β-(methylfumaramido) and 6β-chloroacetamido derivatives 1b and 1c of 6β-amino-7,8-didehydromorphinan and the corresponding 14-hydroxy derivatives 1e and 1f are described. The 7,8-dihydro derivatives of these compounds were synthesized in inactive (2b, c, e, f) as well as in tritiated form (3b, c, e, f).

Original languageEnglish
Pages (from-to)133-136
Number of pages4
JournalHelvetica Chimica Acta
Volume79
Issue number1
Publication statusPublished - 1996

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All Science Journal Classification (ASJC) codes

  • Chemistry(all)

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