TY - JOUR
T1 - 13. Synthesis and tritium labelling of 6β-amino-4,5α-epoxyraorphinans and their 14-hydroxy derivatives as potential affinity labelling probes with μ opioid agonist activity
AU - Ötvös, Ferenc
AU - Tóth, Géza
AU - Lovas, Sándor
AU - Simon, Csaba
AU - Hosztafi, Sándor
PY - 1996
Y1 - 1996
N2 - The synthesis of 6β-(methylfumaramido) and 6β-chloroacetamido derivatives 1b and 1c of 6β-amino-7,8-didehydromorphinan and the corresponding 14-hydroxy derivatives 1e and 1f are described. The 7,8-dihydro derivatives of these compounds were synthesized in inactive (2b, c, e, f) as well as in tritiated form (3b, c, e, f).
AB - The synthesis of 6β-(methylfumaramido) and 6β-chloroacetamido derivatives 1b and 1c of 6β-amino-7,8-didehydromorphinan and the corresponding 14-hydroxy derivatives 1e and 1f are described. The 7,8-dihydro derivatives of these compounds were synthesized in inactive (2b, c, e, f) as well as in tritiated form (3b, c, e, f).
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U2 - 10.1002/hlca.19960790114
DO - 10.1002/hlca.19960790114
M3 - Article
AN - SCOPUS:0041022342
VL - 79
SP - 133
EP - 136
JO - Helvetica Chimica Acta
JF - Helvetica Chimica Acta
SN - 0018-019X
IS - 1
ER -