13. Synthesis and tritium labelling of 6β-amino-4,5α-epoxyraorphinans and their 14-hydroxy derivatives as potential affinity labelling probes with μ opioid agonist activity

Ferenc Ötvös; Géza Tóth; Sándor Lovas; Csaba Simon; Sándor Hosztafi

doi:10.1002/hlca.19960790114

13. Synthesis and tritium labelling of 6β-amino-4,5α-epoxyraorphinans and their 14-hydroxy derivatives as potential affinity labelling probes with μ opioid agonist activity

Ferenc Ötvös, Géza Tóth, Sándor Lovas, Csaba Simon, Sándor Hosztafi

Department of Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

The synthesis of 6β-(methylfumaramido) and 6β-chloroacetamido derivatives 1b and 1c of 6β-amino-7,8-didehydromorphinan and the corresponding 14-hydroxy derivatives 1e and 1f are described. The 7,8-dihydro derivatives of these compounds were synthesized in inactive (2b, c, e, f) as well as in tritiated form (3b, c, e, f).

Original language	English (US)
Pages (from-to)	133-136
Number of pages	4
Journal	Helvetica Chimica Acta
Volume	79
Issue number	1
DOIs	https://doi.org/10.1002/hlca.19960790114
State	Published - 1996

All Science Journal Classification (ASJC) codes

Catalysis
Biochemistry
Drug Discovery
Physical and Theoretical Chemistry
Organic Chemistry
Inorganic Chemistry

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10.1002/hlca.19960790114

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13. Synthesis and tritium labelling of 6β-amino-4,5α-epoxyraorphinans and their 14-hydroxy derivatives as potential affinity labelling probes with μ opioid agonist activity. / Ötvös, Ferenc; Tóth, Géza; Lovas, Sándor; Simon, Csaba; Hosztafi, Sándor.

In: Helvetica Chimica Acta, Vol. 79, No. 1, 1996, p. 133-136.

Research output: Contribution to journal › Article › peer-review

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