2-(1,2,3-Triazol-4-yl)pyridine-containing ethynylarenes as selective 'turn-on' fluorescent chemosensors for Ni(II)

Joseph A. Christensen, James T. Fletcher

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A series of ethynylarene compounds containing 2-(1,2,3-triazol-4-yl)pyridine chelating units were studied as fluorescent chemosensors for metal cations in aqueous solution. Analogs possessing two chelating units bridged by either 1,4-diethynylphenyl or 2,7-diethynylnaphthyl subunits displayed large hypsochromic shifts coupled with signal intensification when exposed to increasing concentrations of Ni(II), a unique response among 22 metal cation analytes. This response was shown to be reversible, and is proposed to derive from disruption of aggregate formation upon Ni(II) binding at the peripheral chelating units.

Original languageEnglish
Pages (from-to)4612-4615
Number of pages4
JournalTetrahedron Letters
Volume55
Issue number33
DOIs
StatePublished - Aug 13 2014

Fingerprint

Chelation
Cations
Metals
pyridine

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

2-(1,2,3-Triazol-4-yl)pyridine-containing ethynylarenes as selective 'turn-on' fluorescent chemosensors for Ni(II). / Christensen, Joseph A.; Fletcher, James T.

In: Tetrahedron Letters, Vol. 55, No. 33, 13.08.2014, p. 4612-4615.

Research output: Contribution to journalArticle

@article{497a1ca1480e40228b6a200182cfd4ba,
title = "2-(1,2,3-Triazol-4-yl)pyridine-containing ethynylarenes as selective 'turn-on' fluorescent chemosensors for Ni(II)",
abstract = "A series of ethynylarene compounds containing 2-(1,2,3-triazol-4-yl)pyridine chelating units were studied as fluorescent chemosensors for metal cations in aqueous solution. Analogs possessing two chelating units bridged by either 1,4-diethynylphenyl or 2,7-diethynylnaphthyl subunits displayed large hypsochromic shifts coupled with signal intensification when exposed to increasing concentrations of Ni(II), a unique response among 22 metal cation analytes. This response was shown to be reversible, and is proposed to derive from disruption of aggregate formation upon Ni(II) binding at the peripheral chelating units.",
author = "Christensen, {Joseph A.} and Fletcher, {James T.}",
year = "2014",
month = "8",
day = "13",
doi = "10.1016/j.tetlet.2014.06.059",
language = "English",
volume = "55",
pages = "4612--4615",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "33",

}

TY - JOUR

T1 - 2-(1,2,3-Triazol-4-yl)pyridine-containing ethynylarenes as selective 'turn-on' fluorescent chemosensors for Ni(II)

AU - Christensen, Joseph A.

AU - Fletcher, James T.

PY - 2014/8/13

Y1 - 2014/8/13

N2 - A series of ethynylarene compounds containing 2-(1,2,3-triazol-4-yl)pyridine chelating units were studied as fluorescent chemosensors for metal cations in aqueous solution. Analogs possessing two chelating units bridged by either 1,4-diethynylphenyl or 2,7-diethynylnaphthyl subunits displayed large hypsochromic shifts coupled with signal intensification when exposed to increasing concentrations of Ni(II), a unique response among 22 metal cation analytes. This response was shown to be reversible, and is proposed to derive from disruption of aggregate formation upon Ni(II) binding at the peripheral chelating units.

AB - A series of ethynylarene compounds containing 2-(1,2,3-triazol-4-yl)pyridine chelating units were studied as fluorescent chemosensors for metal cations in aqueous solution. Analogs possessing two chelating units bridged by either 1,4-diethynylphenyl or 2,7-diethynylnaphthyl subunits displayed large hypsochromic shifts coupled with signal intensification when exposed to increasing concentrations of Ni(II), a unique response among 22 metal cation analytes. This response was shown to be reversible, and is proposed to derive from disruption of aggregate formation upon Ni(II) binding at the peripheral chelating units.

UR - http://www.scopus.com/inward/record.url?scp=84908217621&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84908217621&partnerID=8YFLogxK

U2 - 10.1016/j.tetlet.2014.06.059

DO - 10.1016/j.tetlet.2014.06.059

M3 - Article

AN - SCOPUS:84908217621

VL - 55

SP - 4612

EP - 4615

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 33

ER -