A 75 year old male with recurrent unilateral pleural effusion and positive ANA

Tanner Wallen, Nikhil Jagan, Mridula Krishnan, Zachary Depew

Research output: Contribution to journalArticle

Abstract

This case report describes the clinical course and diagnostic challenges arising in a 75 year old man who initially presented with progressive shortness of breath. Imaging revealed a pleural effusion, which was recurrent following thoracentesis. While his initial workup suggested an autoimmune etiology, further diagnostic testing revealed a diagnosis of malignant pleural mesothelioma. Curiously, the patient had no known asbestos exposure, which is classically associated with acquired mesothelioma. There are a small number of similar cases with a possible overlap between positive autoimmune serologies and mesothelioma; however, the underlying pathophysiology remains elusive. It is the authors' goal to contribute this case to the few cases describing such overlap syndromes.

Original languageEnglish (US)
Pages (from-to)301-303
Number of pages3
JournalRespiratory Medicine Case Reports
Volume26
DOIs
StatePublished - Jan 1 2019
Externally publishedYes

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Mesothelioma
Pleural Effusion
Asbestos
Serology
Dyspnea
Malignant Mesothelioma
Thoracentesis

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine

Cite this

A 75 year old male with recurrent unilateral pleural effusion and positive ANA. / Wallen, Tanner; Jagan, Nikhil; Krishnan, Mridula; Depew, Zachary.

In: Respiratory Medicine Case Reports, Vol. 26, 01.01.2019, p. 301-303.

Research output: Contribution to journalArticle

Wallen, Tanner ; Jagan, Nikhil ; Krishnan, Mridula ; Depew, Zachary. / A 75 year old male with recurrent unilateral pleural effusion and positive ANA. In: Respiratory Medicine Case Reports. 2019 ; Vol. 26. pp. 301-303.
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