A 75 year old male with recurrent unilateral pleural effusion and positive ANA

Tanner Wallen, Nikhil Jagan, Mridula Krishnan, Zachary Depew

Abstract

This case report describes the clinical course and diagnostic challenges arising in a 75 year old man who initially presented with progressive shortness of breath. Imaging revealed a pleural effusion, which was recurrent following thoracentesis. While his initial workup suggested an autoimmune etiology, further diagnostic testing revealed a diagnosis of malignant pleural mesothelioma. Curiously, the patient had no known asbestos exposure, which is classically associated with acquired mesothelioma. There are a small number of similar cases with a possible overlap between positive autoimmune serologies and mesothelioma; however, the underlying pathophysiology remains elusive. It is the authors' goal to contribute this case to the few cases describing such overlap syndromes.

Original languageEnglish (US)
Pages (from-to)301-303
Number of pages3
JournalRespiratory Medicine Case Reports
Volume26
DOIs
Publication statusPublished - Jan 1 2019

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All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine

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