Abstract
This case report describes the clinical course and diagnostic challenges arising in a 75 year old man who initially presented with progressive shortness of breath. Imaging revealed a pleural effusion, which was recurrent following thoracentesis. While his initial workup suggested an autoimmune etiology, further diagnostic testing revealed a diagnosis of malignant pleural mesothelioma. Curiously, the patient had no known asbestos exposure, which is classically associated with acquired mesothelioma. There are a small number of similar cases with a possible overlap between positive autoimmune serologies and mesothelioma; however, the underlying pathophysiology remains elusive. It is the authors' goal to contribute this case to the few cases describing such overlap syndromes.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 301-303 |
| Number of pages | 3 |
| Journal | Respiratory Medicine Case Reports |
| Volume | 26 |
| DOIs | |
| State | Published - Jan 1 2019 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Pulmonary and Respiratory Medicine
Cite this
A 75 year old male with recurrent unilateral pleural effusion and positive ANA. / Wallen, Tanner; Jagan, Nikhil; Krishnan, Mridula; Depew, Zachary.
In: Respiratory Medicine Case Reports, Vol. 26, 01.01.2019, p. 301-303.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A 75 year old male with recurrent unilateral pleural effusion and positive ANA
AU - Wallen, Tanner
AU - Jagan, Nikhil
AU - Krishnan, Mridula
AU - Depew, Zachary
PY - 2019/1/1
Y1 - 2019/1/1
N2 - This case report describes the clinical course and diagnostic challenges arising in a 75 year old man who initially presented with progressive shortness of breath. Imaging revealed a pleural effusion, which was recurrent following thoracentesis. While his initial workup suggested an autoimmune etiology, further diagnostic testing revealed a diagnosis of malignant pleural mesothelioma. Curiously, the patient had no known asbestos exposure, which is classically associated with acquired mesothelioma. There are a small number of similar cases with a possible overlap between positive autoimmune serologies and mesothelioma; however, the underlying pathophysiology remains elusive. It is the authors' goal to contribute this case to the few cases describing such overlap syndromes.
AB - This case report describes the clinical course and diagnostic challenges arising in a 75 year old man who initially presented with progressive shortness of breath. Imaging revealed a pleural effusion, which was recurrent following thoracentesis. While his initial workup suggested an autoimmune etiology, further diagnostic testing revealed a diagnosis of malignant pleural mesothelioma. Curiously, the patient had no known asbestos exposure, which is classically associated with acquired mesothelioma. There are a small number of similar cases with a possible overlap between positive autoimmune serologies and mesothelioma; however, the underlying pathophysiology remains elusive. It is the authors' goal to contribute this case to the few cases describing such overlap syndromes.
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UR - http://www.scopus.com/inward/citedby.url?scp=85062008260&partnerID=8YFLogxK
U2 - 10.1016/j.rmcr.2019.02.019
DO - 10.1016/j.rmcr.2019.02.019
M3 - Article
VL - 26
SP - 301
EP - 303
JO - Respiratory Medicine Case Reports
JF - Respiratory Medicine Case Reports
SN - 2213-0071
ER -