A comparison of stent-induced stenosis in coronary and peripheral arteries

K. D. Krueger, A. K. Mitra, Michael Del Core, W. J. Hunter, Devendra K. Agrawal

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Background and objectives: Restenosis is a complication of interventional procedures such as angioplasty and stenting, often limiting the success of these procedures. Knowledge regarding the relative behaviour of different arteries after these procedures is limited, despite the extensive use of different vascular models. Although the results from studies using different vessels are analysed to predict the behaviour of coronary arteries and other vasculature, direct controlled comparisons between different arteries are necessary for a better understanding of the differential response to restenosis. Methods: This study examines the response to stenting in coronary and internal iliac arteries as characterised by intimal hyperplasia and restenosis. In a swine model of in-stent stenosis, coronary arteries exhibited higher levels of intimal hyperplasia and per cent stenosis than internal iliac arteries. Results: After normalisation for injury score, coronary arteries were found to undergo 47% more intimal hyperplasia (p

Original languageEnglish
Pages (from-to)575-579
Number of pages5
JournalJournal of Clinical Pathology - Clinical Molecular Pathology
Volume59
Issue number6
DOIs
StatePublished - Jun 2006

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Tunica Intima
Stents
Coronary Vessels
Pathologic Constriction
Hyperplasia
Iliac Artery
Arteries
Coronary Stenosis
Angioplasty
Blood Vessels
Swine
Wounds and Injuries

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine

Cite this

A comparison of stent-induced stenosis in coronary and peripheral arteries. / Krueger, K. D.; Mitra, A. K.; Del Core, Michael; Hunter, W. J.; Agrawal, Devendra K.

In: Journal of Clinical Pathology - Clinical Molecular Pathology, Vol. 59, No. 6, 06.2006, p. 575-579.

Research output: Contribution to journalArticle

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