A computer investigation into the origin of the code

Marc S. Rendell

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Quantum mechanical methods are used to simulate interactions between glycine and polynucleotide base sequences. High-magnitude, configurationally specific interactions with features similar to Watson-Crick base pairing are obtained. Glycine manifests preferential affinities in complexing with the stacked base pairs. The feasibility of selective interaction between polar amino acids and polynucleotide base sequences is considered. The implications of such interactions for the origin of the genetic code are discussed.

Original languageEnglish
Pages (from-to)4337-4341
Number of pages5
JournalJournal of the American Chemical Society
Volume94
Issue number12
StatePublished - 1972
Externally publishedYes

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Polynucleotides
Base Pairing
Glycine
Amino acids
Genetic Code
Amino Acids

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

Cite this

A computer investigation into the origin of the code. / Rendell, Marc S.

In: Journal of the American Chemical Society, Vol. 94, No. 12, 1972, p. 4337-4341.

Research output: Contribution to journalArticle

Rendell, Marc S. / A computer investigation into the origin of the code. In: Journal of the American Chemical Society. 1972 ; Vol. 94, No. 12. pp. 4337-4341.
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