A concise synthesis of highly substituted imidazoles via copper-mediated oxidative C-H functionalization

Amit N. Pandya; Devendra K. Agrawal

doi:10.1016/j.tetlet.2014.01.136

A concise synthesis of highly substituted imidazoles via copper-mediated oxidative C-H functionalization

Amit N. Pandya, Devendra K. Agrawal

Department of Clinical and Translational Science

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

We herein report a simple and concise route for the synthesis of highly substituted imidazole derivatives via copper-mediated oxidative C-H functionalization in good to high yields. The advantage of the reaction lies in its mild reaction conditions and readily available starting materials.

Original language	English
Pages (from-to)	1835-1838
Number of pages	4
Journal	Tetrahedron Letters
Volume	55
Issue number	10
DOIs	https://doi.org/10.1016/j.tetlet.2014.01.136
State	Published - Mar 5 2014

All Science Journal Classification (ASJC) codes

Biochemistry
Organic Chemistry
Drug Discovery

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title = "A concise synthesis of highly substituted imidazoles via copper-mediated oxidative C-H functionalization",

abstract = "We herein report a simple and concise route for the synthesis of highly substituted imidazole derivatives via copper-mediated oxidative C-H functionalization in good to high yields. The advantage of the reaction lies in its mild reaction conditions and readily available starting materials.",

author = "Pandya, {Amit N.} and Agrawal, {Devendra K.}",

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AU - Pandya, Amit N.

AU - Agrawal, Devendra K.

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N2 - We herein report a simple and concise route for the synthesis of highly substituted imidazole derivatives via copper-mediated oxidative C-H functionalization in good to high yields. The advantage of the reaction lies in its mild reaction conditions and readily available starting materials.

AB - We herein report a simple and concise route for the synthesis of highly substituted imidazole derivatives via copper-mediated oxidative C-H functionalization in good to high yields. The advantage of the reaction lies in its mild reaction conditions and readily available starting materials.

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M3 - Article

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 10

ER -

A concise synthesis of highly substituted imidazoles via copper-mediated oxidative C-H functionalization

Abstract

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