Abstract
To identify quantitative trait loci (QTLs) that contribute to obesity, we performed a large-scale whole genome linkage scan (WGS) involving 4,102 individuals from 434 Caucasian families. The most pronounced linkage evidence was found at the genomic region 20p11-12 for fat mass (LOD = 3.31) and percentage fat mass (PFM) (LOD = 2.92). We also identified several regions showing suggestive linkage signals (threshold LOD = 1.9) for obesity phenotypes, including 5q35, 8q13, 10p12, and 17q11.
Original language | English (US) |
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Pages (from-to) | 145-148 |
Number of pages | 4 |
Journal | Human Genetics |
Volume | 121 |
Issue number | 1 |
DOIs | |
State | Published - Mar 2007 |
All Science Journal Classification (ASJC) codes
- Genetics
- Genetics(clinical)