A giant cystic pheochromocytoma of the adrenal gland

Zenggang Pan, Susan Repertinger, Caishu Deng, Poonam Sharma

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Adrenal pheochromocytomas are rare catecholamine-secreting tumors that originate from chromaffin cells in the adrenal medulla, and giant pheochromocytomas with cystic changes are particularly rare. We report a case of a 46-year-old man who presented with episodic hypertension and headache. Radiographic studies showed an 18-cm cystic mass in the left upper quadrant of the abdomen; further workups, which included light microscopy, immunohistochemical, and electron microscopic analysis, revealed a pheochromocytoma of the left adrenal gland. Cytogenetic analysis and genetic mutation analyses for von-Hippel-Lindau (VHL), rearranged during transfection (RET), and succinate dehydrogenase complex subunit B (SDHB) genes were also performed but failed to reveal any abnormalities within the tumor cells.

Original languageEnglish (US)
Pages (from-to)133-138
Number of pages6
JournalEndocrine Pathology
Issue number2
StatePublished - Jun 1 2008

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology


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