A giant cystic pheochromocytoma of the adrenal gland

Zenggang Pan, Susan Repertinger, Caishu Deng, Poonam K Sharma

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Adrenal pheochromocytomas are rare catecholamine-secreting tumors that originate from chromaffin cells in the adrenal medulla, and giant pheochromocytomas with cystic changes are particularly rare. We report a case of a 46-year-old man who presented with episodic hypertension and headache. Radiographic studies showed an 18-cm cystic mass in the left upper quadrant of the abdomen; further workups, which included light microscopy, immunohistochemical, and electron microscopic analysis, revealed a pheochromocytoma of the left adrenal gland. Cytogenetic analysis and genetic mutation analyses for von-Hippel-Lindau (VHL), rearranged during transfection (RET), and succinate dehydrogenase complex subunit B (SDHB) genes were also performed but failed to reveal any abnormalities within the tumor cells.

Original languageEnglish
Pages (from-to)133-138
Number of pages6
JournalEndocrine Pathology
Volume19
Issue number2
DOIs
StatePublished - Jun 2008

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Pheochromocytoma
Adrenal Glands
Chromaffin Cells
Adrenal Medulla
Succinate Dehydrogenase
Cytogenetic Analysis
Abdomen
Catecholamines
Transfection
Headache
Neoplasms
Electron Microscopy
Hypertension
Light
Mutation
Genes

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Cite this

A giant cystic pheochromocytoma of the adrenal gland. / Pan, Zenggang; Repertinger, Susan; Deng, Caishu; Sharma, Poonam K.

In: Endocrine Pathology, Vol. 19, No. 2, 06.2008, p. 133-138.

Research output: Contribution to journalArticle

Pan, Zenggang ; Repertinger, Susan ; Deng, Caishu ; Sharma, Poonam K. / A giant cystic pheochromocytoma of the adrenal gland. In: Endocrine Pathology. 2008 ; Vol. 19, No. 2. pp. 133-138.
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