Abstract
Adrenal pheochromocytomas are rare catecholamine-secreting tumors that originate from chromaffin cells in the adrenal medulla, and giant pheochromocytomas with cystic changes are particularly rare. We report a case of a 46-year-old man who presented with episodic hypertension and headache. Radiographic studies showed an 18-cm cystic mass in the left upper quadrant of the abdomen; further workups, which included light microscopy, immunohistochemical, and electron microscopic analysis, revealed a pheochromocytoma of the left adrenal gland. Cytogenetic analysis and genetic mutation analyses for von-Hippel-Lindau (VHL), rearranged during transfection (RET), and succinate dehydrogenase complex subunit B (SDHB) genes were also performed but failed to reveal any abnormalities within the tumor cells.
Original language | English (US) |
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Pages (from-to) | 133-138 |
Number of pages | 6 |
Journal | Endocrine Pathology |
Volume | 19 |
Issue number | 2 |
DOIs | |
State | Published - Jun 1 2008 |
All Science Journal Classification (ASJC) codes
- Pathology and Forensic Medicine
- Endocrinology, Diabetes and Metabolism
- Endocrinology