Abstract
Adrenal pheochromocytomas are rare catecholamine-secreting tumors that originate from chromaffin cells in the adrenal medulla, and giant pheochromocytomas with cystic changes are particularly rare. We report a case of a 46-year-old man who presented with episodic hypertension and headache. Radiographic studies showed an 18-cm cystic mass in the left upper quadrant of the abdomen; further workups, which included light microscopy, immunohistochemical, and electron microscopic analysis, revealed a pheochromocytoma of the left adrenal gland. Cytogenetic analysis and genetic mutation analyses for von-Hippel-Lindau (VHL), rearranged during transfection (RET), and succinate dehydrogenase complex subunit B (SDHB) genes were also performed but failed to reveal any abnormalities within the tumor cells.
| Original language | English |
|---|---|
| Pages (from-to) | 133-138 |
| Number of pages | 6 |
| Journal | Endocrine Pathology |
| Volume | 19 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jun 2008 |
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All Science Journal Classification (ASJC) codes
- Pathology and Forensic Medicine
- Endocrinology
- Endocrinology, Diabetes and Metabolism
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A giant cystic pheochromocytoma of the adrenal gland. / Pan, Zenggang; Repertinger, Susan; Deng, Caishu; Sharma, Poonam K.
In: Endocrine Pathology, Vol. 19, No. 2, 06.2008, p. 133-138.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A giant cystic pheochromocytoma of the adrenal gland
AU - Pan, Zenggang
AU - Repertinger, Susan
AU - Deng, Caishu
AU - Sharma, Poonam K
PY - 2008/6
Y1 - 2008/6
N2 - Adrenal pheochromocytomas are rare catecholamine-secreting tumors that originate from chromaffin cells in the adrenal medulla, and giant pheochromocytomas with cystic changes are particularly rare. We report a case of a 46-year-old man who presented with episodic hypertension and headache. Radiographic studies showed an 18-cm cystic mass in the left upper quadrant of the abdomen; further workups, which included light microscopy, immunohistochemical, and electron microscopic analysis, revealed a pheochromocytoma of the left adrenal gland. Cytogenetic analysis and genetic mutation analyses for von-Hippel-Lindau (VHL), rearranged during transfection (RET), and succinate dehydrogenase complex subunit B (SDHB) genes were also performed but failed to reveal any abnormalities within the tumor cells.
AB - Adrenal pheochromocytomas are rare catecholamine-secreting tumors that originate from chromaffin cells in the adrenal medulla, and giant pheochromocytomas with cystic changes are particularly rare. We report a case of a 46-year-old man who presented with episodic hypertension and headache. Radiographic studies showed an 18-cm cystic mass in the left upper quadrant of the abdomen; further workups, which included light microscopy, immunohistochemical, and electron microscopic analysis, revealed a pheochromocytoma of the left adrenal gland. Cytogenetic analysis and genetic mutation analyses for von-Hippel-Lindau (VHL), rearranged during transfection (RET), and succinate dehydrogenase complex subunit B (SDHB) genes were also performed but failed to reveal any abnormalities within the tumor cells.
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U2 - 10.1007/s12022-008-9016-4
DO - 10.1007/s12022-008-9016-4
M3 - Article
VL - 19
SP - 133
EP - 138
JO - Endocrine Pathology
JF - Endocrine Pathology
SN - 1046-3976
IS - 2
ER -