A long-term comparison of plication configurations for endoluminal gastroplication

Circumferential versus helical

Richard E. Davis, Atif Iqbal, Janese D. Gerhardt, Rebecca A. Welch, Kiran Turaga, Brent Tierney, Mumnoon Haider, Charles Filipi

Research output: Contribution to journalArticle

Abstract

Goals: To determine the long-term efficacy of endoluminal gastroplication (ELGP) and the most effective plication configuration. Background: Endoluminal gastroplication is an intriguing therapy for gastroesophageal reflux disease. We conducted a retrospective review of a prospective experience of patient cohorts comparing outcomes of the circumferential and helical plication patterns. Study: Twenty patients underwent ELGP, with 9 receiving the circumferential (Group 1) and 11 the helical pattern (Group 2). Manometry, endoscopy, and 24-hour pH monitoring were performed at baseline and at 6 months. Symptom scores and medication usage were assessed at baseline, 1, 3, 6, 12, and 18 months. Results: Both groups did not differ significantly from each other with respect to symptom improvement, medication usage, or other variables measured. At 6 months, symptom scores, histamine-2 receptor antagonist (H2RA), proton pump inhibitor usage, and hernia size decreased significantly. No other parameter showed a significant change. At the 18-month follow-up, symptom scores and H2RA usage decreased significantly. Conclusion: ELGP improves heartburn and regurgitation scores at 18 months. Our study suggests that there is no benefit to additional plications when using the helical pattern.

Original languageEnglish
Pages (from-to)869-876
Number of pages8
JournalJournal of Clinical Gastroenterology
Volume39
Issue number10
DOIs
StatePublished - Nov 2005

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Histamine Receptors
Heartburn
Proton Pump Inhibitors
Manometry
Hernia
Gastroesophageal Reflux
Endoscopy
Therapeutics

All Science Journal Classification (ASJC) codes

  • Gastroenterology

Cite this

A long-term comparison of plication configurations for endoluminal gastroplication : Circumferential versus helical. / Davis, Richard E.; Iqbal, Atif; Gerhardt, Janese D.; Welch, Rebecca A.; Turaga, Kiran; Tierney, Brent; Haider, Mumnoon; Filipi, Charles.

In: Journal of Clinical Gastroenterology, Vol. 39, No. 10, 11.2005, p. 869-876.

Research output: Contribution to journalArticle

Davis, Richard E. ; Iqbal, Atif ; Gerhardt, Janese D. ; Welch, Rebecca A. ; Turaga, Kiran ; Tierney, Brent ; Haider, Mumnoon ; Filipi, Charles. / A long-term comparison of plication configurations for endoluminal gastroplication : Circumferential versus helical. In: Journal of Clinical Gastroenterology. 2005 ; Vol. 39, No. 10. pp. 869-876.
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