Abstract
Goals: To determine the long-term efficacy of endoluminal gastroplication (ELGP) and the most effective plication configuration. Background: Endoluminal gastroplication is an intriguing therapy for gastroesophageal reflux disease. We conducted a retrospective review of a prospective experience of patient cohorts comparing outcomes of the circumferential and helical plication patterns. Study: Twenty patients underwent ELGP, with 9 receiving the circumferential (Group 1) and 11 the helical pattern (Group 2). Manometry, endoscopy, and 24-hour pH monitoring were performed at baseline and at 6 months. Symptom scores and medication usage were assessed at baseline, 1, 3, 6, 12, and 18 months. Results: Both groups did not differ significantly from each other with respect to symptom improvement, medication usage, or other variables measured. At 6 months, symptom scores, histamine-2 receptor antagonist (H2RA), proton pump inhibitor usage, and hernia size decreased significantly. No other parameter showed a significant change. At the 18-month follow-up, symptom scores and H2RA usage decreased significantly. Conclusion: ELGP improves heartburn and regurgitation scores at 18 months. Our study suggests that there is no benefit to additional plications when using the helical pattern.
| Original language | English |
|---|---|
| Pages (from-to) | 869-876 |
| Number of pages | 8 |
| Journal | Journal of Clinical Gastroenterology |
| Volume | 39 |
| Issue number | 10 |
| DOIs | |
| State | Published - Nov 2005 |
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All Science Journal Classification (ASJC) codes
- Gastroenterology
Cite this
A long-term comparison of plication configurations for endoluminal gastroplication : Circumferential versus helical. / Davis, Richard E.; Iqbal, Atif; Gerhardt, Janese D.; Welch, Rebecca A.; Turaga, Kiran; Tierney, Brent; Haider, Mumnoon; Filipi, Charles.
In: Journal of Clinical Gastroenterology, Vol. 39, No. 10, 11.2005, p. 869-876.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A long-term comparison of plication configurations for endoluminal gastroplication
T2 - Circumferential versus helical
AU - Davis, Richard E.
AU - Iqbal, Atif
AU - Gerhardt, Janese D.
AU - Welch, Rebecca A.
AU - Turaga, Kiran
AU - Tierney, Brent
AU - Haider, Mumnoon
AU - Filipi, Charles
PY - 2005/11
Y1 - 2005/11
N2 - Goals: To determine the long-term efficacy of endoluminal gastroplication (ELGP) and the most effective plication configuration. Background: Endoluminal gastroplication is an intriguing therapy for gastroesophageal reflux disease. We conducted a retrospective review of a prospective experience of patient cohorts comparing outcomes of the circumferential and helical plication patterns. Study: Twenty patients underwent ELGP, with 9 receiving the circumferential (Group 1) and 11 the helical pattern (Group 2). Manometry, endoscopy, and 24-hour pH monitoring were performed at baseline and at 6 months. Symptom scores and medication usage were assessed at baseline, 1, 3, 6, 12, and 18 months. Results: Both groups did not differ significantly from each other with respect to symptom improvement, medication usage, or other variables measured. At 6 months, symptom scores, histamine-2 receptor antagonist (H2RA), proton pump inhibitor usage, and hernia size decreased significantly. No other parameter showed a significant change. At the 18-month follow-up, symptom scores and H2RA usage decreased significantly. Conclusion: ELGP improves heartburn and regurgitation scores at 18 months. Our study suggests that there is no benefit to additional plications when using the helical pattern.
AB - Goals: To determine the long-term efficacy of endoluminal gastroplication (ELGP) and the most effective plication configuration. Background: Endoluminal gastroplication is an intriguing therapy for gastroesophageal reflux disease. We conducted a retrospective review of a prospective experience of patient cohorts comparing outcomes of the circumferential and helical plication patterns. Study: Twenty patients underwent ELGP, with 9 receiving the circumferential (Group 1) and 11 the helical pattern (Group 2). Manometry, endoscopy, and 24-hour pH monitoring were performed at baseline and at 6 months. Symptom scores and medication usage were assessed at baseline, 1, 3, 6, 12, and 18 months. Results: Both groups did not differ significantly from each other with respect to symptom improvement, medication usage, or other variables measured. At 6 months, symptom scores, histamine-2 receptor antagonist (H2RA), proton pump inhibitor usage, and hernia size decreased significantly. No other parameter showed a significant change. At the 18-month follow-up, symptom scores and H2RA usage decreased significantly. Conclusion: ELGP improves heartburn and regurgitation scores at 18 months. Our study suggests that there is no benefit to additional plications when using the helical pattern.
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UR - http://www.scopus.com/inward/citedby.url?scp=27144481376&partnerID=8YFLogxK
U2 - 10.1097/01.mcg.0000180632.99936.6f
DO - 10.1097/01.mcg.0000180632.99936.6f
M3 - Article
VL - 39
SP - 869
EP - 876
JO - Journal of Clinical Gastroenterology
JF - Journal of Clinical Gastroenterology
SN - 0192-0790
IS - 10
ER -