Abstract
A simple and efficient approach for the synthesis of 2-aminoquinazoline derivatives in moderate to good yields. This reaction employs mild reaction conditions, is metal-free and utilizes readily available starting materials making it a more viable reaction for scale up synthesis and ligand diversity. Notably, this methodology allows for the synthesis of 2-aminoquinazolines using a free amine or cyclic amine enabling structural diversity and good atom economy.
Original language | English (US) |
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Pages (from-to) | 1276-1279 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 58 |
Issue number | 13 |
DOIs | |
State | Published - 2017 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Drug Discovery
- Organic Chemistry