Abstract
Two women had acromegaly due to a pituitary adenoma associated with phaeochromocytoma. Eight additional patients with this combination of tumours have been described by others. Our first patient had sustained hypertension, mild hypercalcaemia, and elevated basal levels of parathyroid hormone and calcitonin associated with malignant phaeochromocytoma and parathyroid hyperplasia. The second patient had episodic hypertension and normal basal serum calcium, parathyroid hormone, and calcitonin levels with a benign cystic phaeochromocytoma. Three patients had parathyroid hyperplasia. A separate group of four patients with phaeochromocytoma and pituitary adenoma without acromegaly has also been reported. These fourteen patients probably represent a non-familial variant of the multiple endocrine neoplasia syndrome. Our findings suggest that acromegalic patients with hyertension should be screened for phaeochromocytoma.
| Original language | English |
|---|---|
| Pages (from-to) | 605-612 |
| Number of pages | 8 |
| Journal | Clinical Endocrinology |
| Volume | 14 |
| Issue number | 6 |
| State | Published - 1981 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Endocrinology
Cite this
Acromegaly and pituitary adenoma with phaeochromocytoma : A variant of multiple endocrine neoplasia. / Anderson, R. J.; Lufkin, E. G.; Sizemore, G. W.; Carney, J. A.; Sheps, S. G.; Silliman, Y. E.
In: Clinical Endocrinology, Vol. 14, No. 6, 1981, p. 605-612.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Acromegaly and pituitary adenoma with phaeochromocytoma
T2 - A variant of multiple endocrine neoplasia
AU - Anderson, R. J.
AU - Lufkin, E. G.
AU - Sizemore, G. W.
AU - Carney, J. A.
AU - Sheps, S. G.
AU - Silliman, Y. E.
PY - 1981
Y1 - 1981
N2 - Two women had acromegaly due to a pituitary adenoma associated with phaeochromocytoma. Eight additional patients with this combination of tumours have been described by others. Our first patient had sustained hypertension, mild hypercalcaemia, and elevated basal levels of parathyroid hormone and calcitonin associated with malignant phaeochromocytoma and parathyroid hyperplasia. The second patient had episodic hypertension and normal basal serum calcium, parathyroid hormone, and calcitonin levels with a benign cystic phaeochromocytoma. Three patients had parathyroid hyperplasia. A separate group of four patients with phaeochromocytoma and pituitary adenoma without acromegaly has also been reported. These fourteen patients probably represent a non-familial variant of the multiple endocrine neoplasia syndrome. Our findings suggest that acromegalic patients with hyertension should be screened for phaeochromocytoma.
AB - Two women had acromegaly due to a pituitary adenoma associated with phaeochromocytoma. Eight additional patients with this combination of tumours have been described by others. Our first patient had sustained hypertension, mild hypercalcaemia, and elevated basal levels of parathyroid hormone and calcitonin associated with malignant phaeochromocytoma and parathyroid hyperplasia. The second patient had episodic hypertension and normal basal serum calcium, parathyroid hormone, and calcitonin levels with a benign cystic phaeochromocytoma. Three patients had parathyroid hyperplasia. A separate group of four patients with phaeochromocytoma and pituitary adenoma without acromegaly has also been reported. These fourteen patients probably represent a non-familial variant of the multiple endocrine neoplasia syndrome. Our findings suggest that acromegalic patients with hyertension should be screened for phaeochromocytoma.
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M3 - Article
VL - 14
SP - 605
EP - 612
JO - Clinical Endocrinology
JF - Clinical Endocrinology
SN - 0300-0664
IS - 6
ER -