Aluminum does not accumulate in teenagers and adults on prolonged parenteral nutrition containing free amino acids

M. B. Heyman; G. L. Klein; A. Wong; R. R. Recker; J. B. Tyrrell; A. C. Alfrey; D. J. Sherrard; D. C. Hohn

doi:10.1177/014860718601000186

Aluminum does not accumulate in teenagers and adults on prolonged parenteral nutrition containing free amino acids

M. B. Heyman, G. L. Klein, A. Wong, R. R. Recker, J. B. Tyrrell, A. C. Alfrey, D. J. Sherrard, D. C. Hohn

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

Prolonged total parenteral nutrition (TPN) with solutions containing hydrolyzed casein has been associated with aluminum accumulation in patients with bone disease. We investigated the effects of free amino acids in TPN solution on plasma, urine, and bone aluminum in 6 patients, 5 of whom had symptoms of bone disease or documented demineralization. No evidence of aluminum accumulation was found. TPN with free amino acids, containing 42 μg aluminum per liter or less, does not lead to aluminum loading in adolescents or adults.

Original language	English (US)
Pages (from-to)	86-87
Number of pages	2
Journal	Journal of Parenteral and Enteral Nutrition
Volume	10
Issue number	1
DOIs	https://doi.org/10.1177/014860718601000186
State	Published - Jan 1 1986
Externally published	Yes

All Science Journal Classification (ASJC) codes

Medicine (miscellaneous)
Nutrition and Dietetics

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10.1177/014860718601000186

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Aluminum does not accumulate in teenagers and adults on prolonged parenteral nutrition containing free amino acids. / Heyman, M. B.; Klein, G. L.; Wong, A.; Recker, R. R.; Tyrrell, J. B.; Alfrey, A. C.; Sherrard, D. J.; Hohn, D. C.

In: Journal of Parenteral and Enteral Nutrition, Vol. 10, No. 1, 01.01.1986, p. 86-87.

Research output: Contribution to journal › Article › peer-review

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abstract = "Prolonged total parenteral nutrition (TPN) with solutions containing hydrolyzed casein has been associated with aluminum accumulation in patients with bone disease. We investigated the effects of free amino acids in TPN solution on plasma, urine, and bone aluminum in 6 patients, 5 of whom had symptoms of bone disease or documented demineralization. No evidence of aluminum accumulation was found. TPN with free amino acids, containing 42 μg aluminum per liter or less, does not lead to aluminum loading in adolescents or adults.",

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AU - Tyrrell, J. B.

AU - Alfrey, A. C.

AU - Sherrard, D. J.

AU - Hohn, D. C.

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N2 - Prolonged total parenteral nutrition (TPN) with solutions containing hydrolyzed casein has been associated with aluminum accumulation in patients with bone disease. We investigated the effects of free amino acids in TPN solution on plasma, urine, and bone aluminum in 6 patients, 5 of whom had symptoms of bone disease or documented demineralization. No evidence of aluminum accumulation was found. TPN with free amino acids, containing 42 μg aluminum per liter or less, does not lead to aluminum loading in adolescents or adults.

AB - Prolonged total parenteral nutrition (TPN) with solutions containing hydrolyzed casein has been associated with aluminum accumulation in patients with bone disease. We investigated the effects of free amino acids in TPN solution on plasma, urine, and bone aluminum in 6 patients, 5 of whom had symptoms of bone disease or documented demineralization. No evidence of aluminum accumulation was found. TPN with free amino acids, containing 42 μg aluminum per liter or less, does not lead to aluminum loading in adolescents or adults.

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Aluminum does not accumulate in teenagers and adults on prolonged parenteral nutrition containing free amino acids

Abstract

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