Abstract
Allenyl enolates generated from 1,6 additions of organocopper reagents to 3-ethynyl-2-cycloalkenones act as ambident α,γ-nucleophiles. The γ:α ratio of products is a function of carbon hybridization, steric environment, and cycloalkenone ring size; typically, γ-products predominate.
| Original language | English |
|---|---|
| Pages (from-to) | 185-188 |
| Number of pages | 4 |
| Journal | Tetrahedron Letters |
| Volume | 33 |
| Issue number | 2 |
| DOIs | |
| State | Published - 1992 |
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All Science Journal Classification (ASJC) codes
- Biochemistry
- Organic Chemistry
- Drug Discovery
Cite this
Ambiphilic allenyl enolates : reactions with electrophiles. / Lee, Sang Ho; Shih, Mei Jue; Hulce, Martin.
In: Tetrahedron Letters, Vol. 33, No. 2, 1992, p. 185-188.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Ambiphilic allenyl enolates
T2 - reactions with electrophiles
AU - Lee, Sang Ho
AU - Shih, Mei Jue
AU - Hulce, Martin
PY - 1992
Y1 - 1992
N2 - Allenyl enolates generated from 1,6 additions of organocopper reagents to 3-ethynyl-2-cycloalkenones act as ambident α,γ-nucleophiles. The γ:α ratio of products is a function of carbon hybridization, steric environment, and cycloalkenone ring size; typically, γ-products predominate.
AB - Allenyl enolates generated from 1,6 additions of organocopper reagents to 3-ethynyl-2-cycloalkenones act as ambident α,γ-nucleophiles. The γ:α ratio of products is a function of carbon hybridization, steric environment, and cycloalkenone ring size; typically, γ-products predominate.
UR - http://www.scopus.com/inward/record.url?scp=0026512560&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026512560&partnerID=8YFLogxK
U2 - 10.1016/0040-4039(92)88045-7
DO - 10.1016/0040-4039(92)88045-7
M3 - Article
AN - SCOPUS:0026512560
VL - 33
SP - 185
EP - 188
JO - Tetrahedron Letters
JF - Tetrahedron Letters
SN - 0040-4039
IS - 2
ER -