Abstract
Allenyl enolates generated from 1,6 additions of organocopper reagents to 3-ethynyl-2-cycloalkenones act as ambident α,γ-nucleophiles. The γ:α ratio of products is a function of carbon hybridization, steric environment, and cycloalkenone ring size; typically, γ-products predominate.
Original language | English (US) |
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Pages (from-to) | 185-188 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 33 |
Issue number | 2 |
DOIs | |
State | Published - 1992 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Drug Discovery
- Organic Chemistry