An inositol phosphate as a calcium absorption enhancer in rats

Xin Shen, Connie M. Weaver, Anna Kempa-Steczko, Berdine R. Martin, Brian Q. Phillippy, Robert P. Heaney

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Certain inositol phosphate breakdown compounds have been shown to chelate and increase the solubility of minerals. A rat model using femur uptake of 45Ca was tested for its ability to screen the effect of inositol phosphytate breakdown products on enhancing calcium absorption. Phytate was shown to inhibit calcium absorption in a dose-related manner. A significant enhancing effect of 1,2,3,6-tetraphosphate on calcium absorption was found at the highest level studies (P <0.05), which suggests that this compound may ne a candidate for enhancing calcium absorption.

Original languageEnglish (US)
Pages (from-to)298-301
Number of pages4
JournalJournal of Nutritional Biochemistry
Issue number5
StatePublished - May 1998

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Molecular Biology
  • Nutrition and Dietetics
  • Clinical Biochemistry


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