Abstract
Certain inositol phosphate breakdown compounds have been shown to chelate and increase the solubility of minerals. A rat model using femur uptake of 45Ca was tested for its ability to screen the effect of inositol phosphytate breakdown products on enhancing calcium absorption. Phytate was shown to inhibit calcium absorption in a dose-related manner. A significant enhancing effect of 1,2,3,6-tetraphosphate on calcium absorption was found at the highest level studies (P <0.05), which suggests that this compound may ne a candidate for enhancing calcium absorption.
| Original language | English |
|---|---|
| Pages (from-to) | 298-301 |
| Number of pages | 4 |
| Journal | Journal of Nutritional Biochemistry |
| Volume | 9 |
| Issue number | 5 |
| DOIs | |
| State | Published - May 1998 |
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All Science Journal Classification (ASJC) codes
- Biochemistry
- Endocrinology, Diabetes and Metabolism
Cite this
An inositol phosphate as a calcium absorption enhancer in rats. / Shen, Xin; Weaver, Connie M.; Kempa-Steczko, Anna; Martin, Berdine R.; Phillippy, Brian Q.; Heaney, Robert P.
In: Journal of Nutritional Biochemistry, Vol. 9, No. 5, 05.1998, p. 298-301.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - An inositol phosphate as a calcium absorption enhancer in rats
AU - Shen, Xin
AU - Weaver, Connie M.
AU - Kempa-Steczko, Anna
AU - Martin, Berdine R.
AU - Phillippy, Brian Q.
AU - Heaney, Robert P.
PY - 1998/5
Y1 - 1998/5
N2 - Certain inositol phosphate breakdown compounds have been shown to chelate and increase the solubility of minerals. A rat model using femur uptake of 45Ca was tested for its ability to screen the effect of inositol phosphytate breakdown products on enhancing calcium absorption. Phytate was shown to inhibit calcium absorption in a dose-related manner. A significant enhancing effect of 1,2,3,6-tetraphosphate on calcium absorption was found at the highest level studies (P <0.05), which suggests that this compound may ne a candidate for enhancing calcium absorption.
AB - Certain inositol phosphate breakdown compounds have been shown to chelate and increase the solubility of minerals. A rat model using femur uptake of 45Ca was tested for its ability to screen the effect of inositol phosphytate breakdown products on enhancing calcium absorption. Phytate was shown to inhibit calcium absorption in a dose-related manner. A significant enhancing effect of 1,2,3,6-tetraphosphate on calcium absorption was found at the highest level studies (P <0.05), which suggests that this compound may ne a candidate for enhancing calcium absorption.
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UR - http://www.scopus.com/inward/citedby.url?scp=0032078188&partnerID=8YFLogxK
U2 - 10.1016/S0955-2863(98)00020-5
DO - 10.1016/S0955-2863(98)00020-5
M3 - Article
VL - 9
SP - 298
EP - 301
JO - Journal of Nutritional Biochemistry
JF - Journal of Nutritional Biochemistry
SN - 0955-2863
IS - 5
ER -