Antihyperlipidemic statins: A self-contained, clinically relevant medicinal chemistry lesson

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29 Citations (Scopus)

Abstract

Medicinal chemistry instruction at Creighton University is designed to provide an in-depth, scientifically grounded and clinically relevant learning experience for pharmacy students. Each topic covered in the 2-semester required course sequence is selected based on the general utility of the compounds in question and/or the therapeutic importance of the drugs in treating life-threatening diseases. All lessons provided to campus- and Internet-based students by the author are in the form of a descriptive and conversational narrative, and course requirements are in place to assure that students read the lesson prior to the class period in which it is discussed. Learning tools and aids are provided to help students readily discern the most critical aspects of each lesson, to practice required critical thinking and analysis skills, and to self-assess competency in meeting specific learning objectives. This manuscript illustrates this approach by sharing a lesson on the chemistry and clinically relevant structure-activity relationships of antihyperlipidemic statins, and the tools utilized to optimize learning of the lesson's important chemical and therapeutic messages.

Original languageEnglish
Article number77
Pages (from-to)546-560
Number of pages15
JournalAmerican Journal of Pharmaceutical Education
Volume69
Issue number4
StatePublished - 2005

Fingerprint

Hypolipidemic Agents
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Pharmaceutical Chemistry
chemistry
Learning
Students
chemistry instruction
student
Pharmacy Students
learning
activity structure
learning objective
Structure-Activity Relationship
Internet
semester
drug
Disease
narrative
Therapeutics
Pharmaceutical Preparations

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Education

Cite this

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