Abstract
It has been shown that the arterial baroreflex is depressed in heart failure. The role of alterations in afferent discharge as a possible mechanism for this depression has not been investigated previously. Single unit aortic baroreceptor activity was recorded from six normal dogs and from nine dogs, each with a chronic aorto-caval fistula (AVF). At the time of the acute experiment, mean arterial blood pressure (MABP) was not significantly different in the two groups of dogs; however, pulse pressure was significantly higher in the AVF dogs (45.7±2.4 mm Hg vs, 24.4±2.0 mm Hg; p
| Original language | English |
|---|---|
| Pages (from-to) | 111-122 |
| Number of pages | 12 |
| Journal | Basic Research in Cardiology |
| Volume | 81 |
| Issue number | 2 |
| DOIs | |
| State | Published - Mar 1986 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Cardiology and Cardiovascular Medicine
Cite this
Aortic baroreceptor characteristics in dogs with chronic high output failure. / Niebauer, M. J.; Holmberg, Mark Jeffrey; Zucker, I. H.
In: Basic Research in Cardiology, Vol. 81, No. 2, 03.1986, p. 111-122.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Aortic baroreceptor characteristics in dogs with chronic high output failure
AU - Niebauer, M. J.
AU - Holmberg, Mark Jeffrey
AU - Zucker, I. H.
PY - 1986/3
Y1 - 1986/3
N2 - It has been shown that the arterial baroreflex is depressed in heart failure. The role of alterations in afferent discharge as a possible mechanism for this depression has not been investigated previously. Single unit aortic baroreceptor activity was recorded from six normal dogs and from nine dogs, each with a chronic aorto-caval fistula (AVF). At the time of the acute experiment, mean arterial blood pressure (MABP) was not significantly different in the two groups of dogs; however, pulse pressure was significantly higher in the AVF dogs (45.7±2.4 mm Hg vs, 24.4±2.0 mm Hg; p
AB - It has been shown that the arterial baroreflex is depressed in heart failure. The role of alterations in afferent discharge as a possible mechanism for this depression has not been investigated previously. Single unit aortic baroreceptor activity was recorded from six normal dogs and from nine dogs, each with a chronic aorto-caval fistula (AVF). At the time of the acute experiment, mean arterial blood pressure (MABP) was not significantly different in the two groups of dogs; however, pulse pressure was significantly higher in the AVF dogs (45.7±2.4 mm Hg vs, 24.4±2.0 mm Hg; p
UR - http://www.scopus.com/inward/record.url?scp=0022575832&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0022575832&partnerID=8YFLogxK
U2 - 10.1007/BF01907376
DO - 10.1007/BF01907376
M3 - Article
VL - 81
SP - 111
EP - 122
JO - Basic Research in Cardiology
JF - Basic Research in Cardiology
SN - 0300-8428
IS - 2
ER -