Aortic baroreceptor characteristics in dogs with chronic high output failure

M. J. Niebauer; M. J. Holmberg; I. H. Zucker

doi:10.1007/BF01907376

Aortic baroreceptor characteristics in dogs with chronic high output failure

M. J. Niebauer, M. J. Holmberg, I. H. Zucker

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

It has been shown that the arterial baroreflex is depressed in heart failure. The role of alterations in afferent discharge as a possible mechanism for this depression has not been investigated previously. Single unit aortic baroreceptor activity was recorded from six normal dogs and from nine dogs, each with a chronic aorto-caval fistula (AVF). At the time of the acute experiment, mean arterial blood pressure (MABP) was not significantly different in the two groups of dogs; however, pulse pressure was significantly higher in the AVF dogs (45.7±2.4 mm Hg vs, 24.4±2.0 mm Hg; p

Original language	English (US)
Pages (from-to)	111-122
Number of pages	12
Journal	Basic Research in Cardiology
Volume	81
Issue number	2
DOIs	https://doi.org/10.1007/BF01907376
State	Published - Mar 1 1986
Externally published	Yes

All Science Journal Classification (ASJC) codes

Physiology
Cardiology and Cardiovascular Medicine
Physiology (medical)

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AB - It has been shown that the arterial baroreflex is depressed in heart failure. The role of alterations in afferent discharge as a possible mechanism for this depression has not been investigated previously. Single unit aortic baroreceptor activity was recorded from six normal dogs and from nine dogs, each with a chronic aorto-caval fistula (AVF). At the time of the acute experiment, mean arterial blood pressure (MABP) was not significantly different in the two groups of dogs; however, pulse pressure was significantly higher in the AVF dogs (45.7±2.4 mm Hg vs, 24.4±2.0 mm Hg; p

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Aortic baroreceptor characteristics in dogs with chronic high output failure

Abstract

All Science Journal Classification (ASJC) codes

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