Abstract
It has been shown that the arterial baroreflex is depressed in heart failure. The role of alterations in afferent discharge as a possible mechanism for this depression has not been investigated previously. Single unit aortic baroreceptor activity was recorded from six normal dogs and from nine dogs, each with a chronic aorto-caval fistula (AVF). At the time of the acute experiment, mean arterial blood pressure (MABP) was not significantly different in the two groups of dogs; however, pulse pressure was significantly higher in the AVF dogs (45.7±2.4 mm Hg vs, 24.4±2.0 mm Hg; p
| Original language | English (US) |
|---|---|
| Pages (from-to) | 111-122 |
| Number of pages | 12 |
| Journal | Basic Research in Cardiology |
| Volume | 81 |
| Issue number | 2 |
| DOIs | |
| State | Published - Mar 1 1986 |
All Science Journal Classification (ASJC) codes
- Physiology
- Cardiology and Cardiovascular Medicine
- Physiology (medical)
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Cite this
Niebauer, M. J., Holmberg, M. J., & Zucker, I. H. (1986). Aortic baroreceptor characteristics in dogs with chronic high output failure. Basic Research in Cardiology, 81(2), 111-122. https://doi.org/10.1007/BF01907376