Aortic baroreceptor characteristics in dogs with chronic high output failure

M. J. Niebauer, Mark Jeffrey Holmberg, I. H. Zucker

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

It has been shown that the arterial baroreflex is depressed in heart failure. The role of alterations in afferent discharge as a possible mechanism for this depression has not been investigated previously. Single unit aortic baroreceptor activity was recorded from six normal dogs and from nine dogs, each with a chronic aorto-caval fistula (AVF). At the time of the acute experiment, mean arterial blood pressure (MABP) was not significantly different in the two groups of dogs; however, pulse pressure was significantly higher in the AVF dogs (45.7±2.4 mm Hg vs, 24.4±2.0 mm Hg; p

Original languageEnglish
Pages (from-to)111-122
Number of pages12
JournalBasic Research in Cardiology
Volume81
Issue number2
DOIs
StatePublished - Mar 1986
Externally publishedYes

Fingerprint

Pressoreceptors
Dogs
Venae Cavae
Fistula
Arterial Pressure
Baroreflex
Heart Failure
Blood Pressure

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Aortic baroreceptor characteristics in dogs with chronic high output failure. / Niebauer, M. J.; Holmberg, Mark Jeffrey; Zucker, I. H.

In: Basic Research in Cardiology, Vol. 81, No. 2, 03.1986, p. 111-122.

Research output: Contribution to journalArticle

@article{b03039d4dcb6438ba9e81a5601856db9,
title = "Aortic baroreceptor characteristics in dogs with chronic high output failure",
abstract = "It has been shown that the arterial baroreflex is depressed in heart failure. The role of alterations in afferent discharge as a possible mechanism for this depression has not been investigated previously. Single unit aortic baroreceptor activity was recorded from six normal dogs and from nine dogs, each with a chronic aorto-caval fistula (AVF). At the time of the acute experiment, mean arterial blood pressure (MABP) was not significantly different in the two groups of dogs; however, pulse pressure was significantly higher in the AVF dogs (45.7±2.4 mm Hg vs, 24.4±2.0 mm Hg; p",
author = "Niebauer, {M. J.} and Holmberg, {Mark Jeffrey} and Zucker, {I. H.}",
year = "1986",
month = "3",
doi = "10.1007/BF01907376",
language = "English",
volume = "81",
pages = "111--122",
journal = "Basic Research in Cardiology",
issn = "0300-8428",
publisher = "D. Steinkopff-Verlag",
number = "2",

}

TY - JOUR

T1 - Aortic baroreceptor characteristics in dogs with chronic high output failure

AU - Niebauer, M. J.

AU - Holmberg, Mark Jeffrey

AU - Zucker, I. H.

PY - 1986/3

Y1 - 1986/3

N2 - It has been shown that the arterial baroreflex is depressed in heart failure. The role of alterations in afferent discharge as a possible mechanism for this depression has not been investigated previously. Single unit aortic baroreceptor activity was recorded from six normal dogs and from nine dogs, each with a chronic aorto-caval fistula (AVF). At the time of the acute experiment, mean arterial blood pressure (MABP) was not significantly different in the two groups of dogs; however, pulse pressure was significantly higher in the AVF dogs (45.7±2.4 mm Hg vs, 24.4±2.0 mm Hg; p

AB - It has been shown that the arterial baroreflex is depressed in heart failure. The role of alterations in afferent discharge as a possible mechanism for this depression has not been investigated previously. Single unit aortic baroreceptor activity was recorded from six normal dogs and from nine dogs, each with a chronic aorto-caval fistula (AVF). At the time of the acute experiment, mean arterial blood pressure (MABP) was not significantly different in the two groups of dogs; however, pulse pressure was significantly higher in the AVF dogs (45.7±2.4 mm Hg vs, 24.4±2.0 mm Hg; p

UR - http://www.scopus.com/inward/record.url?scp=0022575832&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022575832&partnerID=8YFLogxK

U2 - 10.1007/BF01907376

DO - 10.1007/BF01907376

M3 - Article

VL - 81

SP - 111

EP - 122

JO - Basic Research in Cardiology

JF - Basic Research in Cardiology

SN - 0300-8428

IS - 2

ER -