INTRODUCTION: This case series illustrates the use of the new classification system of periodontal diseases and conditions. This case series highlights how the assessment of the rate of progression of periodontal disease, that is, grading, allows for the identification of individual patients, who are more likely to require active periodontal treatment intervention to prevent onset of disease, need long-term disease control, or referral to a periodontist. CASE PRESENTATION: A 17-year-old female presents with slight gingival inflammation. However, exploration into indirect evidence of disease progression, that is, family history of periodontal disease, leads to the discovery of advanced disease in the mother. The patient was diagnosed with generalized Stage I Grade C periodontitis. The patient was managed with initial periodontal therapy, consisting of scaling and root planing with systemic antibiotic therapy. Special consideration was taken to mitigate the potential for rapid disease progression because of indirect evidence of familial history of aggressive periodontitis and indicated the need for early intervention. The case resulted in remission of the progression of periodontal disease. CONCLUSIONS: Applying the staging and grading system leads to an understanding of the need for periodontal referral and early periodontal treatment intervention. Wide adoption of staging and grading could increase early referral leading to early periodontal treatment intervention, decreased tooth loss, and have a potential effect on overall health improvement and wellness.