Abstract
A radiometric assay for the determination of AHH activity in lymphocytes is described. Subjects included eleven male patients with histologically verified lung cancer (nine squamous cell car-cinoma and two adenocarcinoma) and eleven age-and sex-matched controls. Lung cancer patients exhibited considerably greater varia-tion and elevated levels of both AHH activity per se and AHH activity adjusted for total cellular DNA than control individuals. Methodology for AHH determinations and implications for lung cancer epidemiology and control are discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 105-109 |
| Number of pages | 5 |
| Journal | Oncology |
| Volume | 33 |
| Issue number | 3 |
| DOIs | |
| State | Published - 1976 |
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All Science Journal Classification (ASJC) codes
- Cancer Research
- Oncology
Cite this
Aryl-hydrocarbon hydroxylase activity in lymphocytes from lung cancer patients and normal controls. / Guirgis, H. A.; Lynch, Henry T.; Mate, T.; Harris, R. E.; Wells, I.; Caha, L.; Anderson, J.; Maloney, K.; Rankin, L.
In: Oncology, Vol. 33, No. 3, 1976, p. 105-109.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Aryl-hydrocarbon hydroxylase activity in lymphocytes from lung cancer patients and normal controls
AU - Guirgis, H. A.
AU - Lynch, Henry T.
AU - Mate, T.
AU - Harris, R. E.
AU - Wells, I.
AU - Caha, L.
AU - Anderson, J.
AU - Maloney, K.
AU - Rankin, L.
PY - 1976
Y1 - 1976
N2 - A radiometric assay for the determination of AHH activity in lymphocytes is described. Subjects included eleven male patients with histologically verified lung cancer (nine squamous cell car-cinoma and two adenocarcinoma) and eleven age-and sex-matched controls. Lung cancer patients exhibited considerably greater varia-tion and elevated levels of both AHH activity per se and AHH activity adjusted for total cellular DNA than control individuals. Methodology for AHH determinations and implications for lung cancer epidemiology and control are discussed.
AB - A radiometric assay for the determination of AHH activity in lymphocytes is described. Subjects included eleven male patients with histologically verified lung cancer (nine squamous cell car-cinoma and two adenocarcinoma) and eleven age-and sex-matched controls. Lung cancer patients exhibited considerably greater varia-tion and elevated levels of both AHH activity per se and AHH activity adjusted for total cellular DNA than control individuals. Methodology for AHH determinations and implications for lung cancer epidemiology and control are discussed.
UR - http://www.scopus.com/inward/record.url?scp=0017056286&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0017056286&partnerID=8YFLogxK
U2 - 10.1159/000225116
DO - 10.1159/000225116
M3 - Article
C2 - 1012643
AN - SCOPUS:0017056286
VL - 33
SP - 105
EP - 109
JO - Oncology
JF - Oncology
SN - 0030-2414
IS - 3
ER -