Assessing vitamin D status

Robert P. Heaney

Research output: Contribution to journalReview article

41 Citations (Scopus)

Abstract

Purpose of Review: To characterize methods evaluating and to summarize studies linking various serum 25-hydroxyvitamin D [25(OH)D] concentrations with health status. Recent Findings: Elucidation of the cell-biologic mechanism of vitamin D action, and numerous clinical trials and observational studies relating vitamin D status to health and disease. Conclusion: The distinction between deficiency and insufficiency is not useful or necessary. Serum 25(OH)D values below 120 nmol/l (48 ng/ml) are associated with preventable disease and are therefore indicative of deficiency. The upper limit of the normal range can be set at 225 nmol/l (90 ng/ml), although toxicity is rare below 500 nmol/l (200 ng/ml).

Original languageEnglish
Pages (from-to)440-444
Number of pages5
JournalCurrent Opinion in Clinical Nutrition and Metabolic Care
Volume14
Issue number5
DOIs
StatePublished - Sep 2011

Fingerprint

Vitamin D
Health Status
Biological Products
Serum
Observational Studies
Reference Values
Clinical Trials
25-hydroxyvitamin D
Clinical Studies

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Assessing vitamin D status. / Heaney, Robert P.

In: Current Opinion in Clinical Nutrition and Metabolic Care, Vol. 14, No. 5, 09.2011, p. 440-444.

Research output: Contribution to journalReview article

Heaney, Robert P. / Assessing vitamin D status. In: Current Opinion in Clinical Nutrition and Metabolic Care. 2011 ; Vol. 14, No. 5. pp. 440-444.
@article{9f8c14273c314f1996198c604131c0ec,
title = "Assessing vitamin D status",
abstract = "Purpose of Review: To characterize methods evaluating and to summarize studies linking various serum 25-hydroxyvitamin D [25(OH)D] concentrations with health status. Recent Findings: Elucidation of the cell-biologic mechanism of vitamin D action, and numerous clinical trials and observational studies relating vitamin D status to health and disease. Conclusion: The distinction between deficiency and insufficiency is not useful or necessary. Serum 25(OH)D values below 120 nmol/l (48 ng/ml) are associated with preventable disease and are therefore indicative of deficiency. The upper limit of the normal range can be set at 225 nmol/l (90 ng/ml), although toxicity is rare below 500 nmol/l (200 ng/ml).",
author = "Heaney, {Robert P.}",
year = "2011",
month = "9",
doi = "10.1097/MCO.0b013e328348ed85",
language = "English",
volume = "14",
pages = "440--444",
journal = "Current Opinion in Clinical Nutrition and Metabolic Care",
issn = "1363-1950",
publisher = "Lippincott Williams and Wilkins",
number = "5",

}

TY - JOUR

T1 - Assessing vitamin D status

AU - Heaney, Robert P.

PY - 2011/9

Y1 - 2011/9

N2 - Purpose of Review: To characterize methods evaluating and to summarize studies linking various serum 25-hydroxyvitamin D [25(OH)D] concentrations with health status. Recent Findings: Elucidation of the cell-biologic mechanism of vitamin D action, and numerous clinical trials and observational studies relating vitamin D status to health and disease. Conclusion: The distinction between deficiency and insufficiency is not useful or necessary. Serum 25(OH)D values below 120 nmol/l (48 ng/ml) are associated with preventable disease and are therefore indicative of deficiency. The upper limit of the normal range can be set at 225 nmol/l (90 ng/ml), although toxicity is rare below 500 nmol/l (200 ng/ml).

AB - Purpose of Review: To characterize methods evaluating and to summarize studies linking various serum 25-hydroxyvitamin D [25(OH)D] concentrations with health status. Recent Findings: Elucidation of the cell-biologic mechanism of vitamin D action, and numerous clinical trials and observational studies relating vitamin D status to health and disease. Conclusion: The distinction between deficiency and insufficiency is not useful or necessary. Serum 25(OH)D values below 120 nmol/l (48 ng/ml) are associated with preventable disease and are therefore indicative of deficiency. The upper limit of the normal range can be set at 225 nmol/l (90 ng/ml), although toxicity is rare below 500 nmol/l (200 ng/ml).

UR - http://www.scopus.com/inward/record.url?scp=80051706694&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80051706694&partnerID=8YFLogxK

U2 - 10.1097/MCO.0b013e328348ed85

DO - 10.1097/MCO.0b013e328348ed85

M3 - Review article

C2 - 21832900

AN - SCOPUS:80051706694

VL - 14

SP - 440

EP - 444

JO - Current Opinion in Clinical Nutrition and Metabolic Care

JF - Current Opinion in Clinical Nutrition and Metabolic Care

SN - 1363-1950

IS - 5

ER -