TY - JOUR
T1 - Bariatric surgery, safety and type 2 diabetes
AU - Spanakis, Elias
AU - Gragnoli, Claudia
N1 - Funding Information:
Acknowledgments This study was made possible by the Penn State University Dean’s Pilot and Feasibility Grant and by grant number D1BTH06321–01 from the Office for the Advancement of Telehealth, Health Resources and Services Administration, Department of Health and Human Services. This project is funded, in part, under a grant from the Pennsylvania Department of Health using Tobacco Settlement Funds. The Department specifically disclaims responsibility for any analyses, interpretations, or conclusions.
PY - 2009/3
Y1 - 2009/3
N2 - Obesity and type 2 diabetes (T2D) represent major health concerns in the USA. Weight loss is the most important aspect in T2D management, as it reduces both morbidity and mortality. Available lifestyle, behavioral, and pharmacological strategies provide just mild to moderate weight loss. The greatest degree of T2D prevention or T2D amelioration in obese subjects has been reported in subjects who underwent bariatric surgery. In the current review, we will describe various types of bariatric surgery, related safety profiles, and their effect on T2D, as well as the potential mechanisms involved in the remission of T2D. Finally, we hereby examine whether bariatric surgery may be considered a treatment for T2D in pregnant women, children, adolescents and subjects at least 65 years old.
AB - Obesity and type 2 diabetes (T2D) represent major health concerns in the USA. Weight loss is the most important aspect in T2D management, as it reduces both morbidity and mortality. Available lifestyle, behavioral, and pharmacological strategies provide just mild to moderate weight loss. The greatest degree of T2D prevention or T2D amelioration in obese subjects has been reported in subjects who underwent bariatric surgery. In the current review, we will describe various types of bariatric surgery, related safety profiles, and their effect on T2D, as well as the potential mechanisms involved in the remission of T2D. Finally, we hereby examine whether bariatric surgery may be considered a treatment for T2D in pregnant women, children, adolescents and subjects at least 65 years old.
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U2 - 10.1007/s11695-008-9687-4
DO - 10.1007/s11695-008-9687-4
M3 - Review article
C2 - 18830788
AN - SCOPUS:65449179583
VL - 19
SP - 363
EP - 368
JO - Obesity Surgery
JF - Obesity Surgery
SN - 0960-8923
IS - 3
ER -