Abstract
Outpatient transesophageal echocardiography was performed in a 69-year- old man with a history of aortic valve repair. During the procedure the patient became markedly cyanotic and hypotensive. Oxygen saturation measured by pulse oximetry decreased from 97% to the mid-80s. The man's condition continued to deteriorate. On transfer to a critical care unit, blood analysis by co-oximetry showed methemoglobin saturation of 67.8%. The patient's condition improved significantly after intravenous administration of methylene blue 1 mg/kg. With increasing numbers of outpatient procedures performed under topical anesthesia, measures should be in place to deal with a potential life-threatening adverse event such as methemoglobinemia.
| Original language | English |
|---|---|
| Pages (from-to) | 735-738 |
| Number of pages | 4 |
| Journal | Pharmacotherapy |
| Volume | 20 |
| Issue number | 6 I |
| State | Published - 2000 |
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All Science Journal Classification (ASJC) codes
- Pharmacology (medical)
- Pharmacology, Toxicology and Pharmaceutics(all)
Cite this
Benzocaine-induced methemoglobinemia during an outpatient procedure. / Wurdeman, Richard L.; Mohiuddin, Syed M.; Holmberg, Mark Jeffrey; Shalaby, Alaa.
In: Pharmacotherapy, Vol. 20, No. 6 I, 2000, p. 735-738.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Benzocaine-induced methemoglobinemia during an outpatient procedure
AU - Wurdeman, Richard L.
AU - Mohiuddin, Syed M.
AU - Holmberg, Mark Jeffrey
AU - Shalaby, Alaa
PY - 2000
Y1 - 2000
N2 - Outpatient transesophageal echocardiography was performed in a 69-year- old man with a history of aortic valve repair. During the procedure the patient became markedly cyanotic and hypotensive. Oxygen saturation measured by pulse oximetry decreased from 97% to the mid-80s. The man's condition continued to deteriorate. On transfer to a critical care unit, blood analysis by co-oximetry showed methemoglobin saturation of 67.8%. The patient's condition improved significantly after intravenous administration of methylene blue 1 mg/kg. With increasing numbers of outpatient procedures performed under topical anesthesia, measures should be in place to deal with a potential life-threatening adverse event such as methemoglobinemia.
AB - Outpatient transesophageal echocardiography was performed in a 69-year- old man with a history of aortic valve repair. During the procedure the patient became markedly cyanotic and hypotensive. Oxygen saturation measured by pulse oximetry decreased from 97% to the mid-80s. The man's condition continued to deteriorate. On transfer to a critical care unit, blood analysis by co-oximetry showed methemoglobin saturation of 67.8%. The patient's condition improved significantly after intravenous administration of methylene blue 1 mg/kg. With increasing numbers of outpatient procedures performed under topical anesthesia, measures should be in place to deal with a potential life-threatening adverse event such as methemoglobinemia.
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UR - http://www.scopus.com/inward/citedby.url?scp=0034080538&partnerID=8YFLogxK
M3 - Article
C2 - 10853630
AN - SCOPUS:0034080538
VL - 20
SP - 735
EP - 738
JO - Pharmacotherapy
JF - Pharmacotherapy
SN - 0277-0008
IS - 6 I
ER -