Bone Biopsy and Histomorphometry in Clinical Practice

Robert R. Recker

doi:10.1002/9781118453926.ch36

Bone Biopsy and Histomorphometry in Clinical Practice

Robert R. Recker

Department of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

5 Scopus citations

Abstract

This chapter reviews the underlying organization and function of bone cells and identifies a set of basic structural and kinetic histomorphometric variables. Bone biopsy specimens for histomorphometric examination are ordinarily obtained at the transilial site and shipped to specialized laboratories for processing and microscopic analysis. The chapter outlines an approach to interpretation of findings, with examples from a range of metabolic bone diseases. It describes techniques for obtaining, processing, and analyzing transilial biopsy specimens. The chapter discusses clinical situations in which bone histomorphometry can be useful, and relates histomorphometric measures to data from other methods for assessing bone properties and bone physiology.

Original language	English (US)
Title of host publication	Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism: Eighth Edition
Publisher	Wiley Blackwell
Pages	307-316
Number of pages	10
ISBN (Electronic)	9781118453926
ISBN (Print)	9781118453889
DOIs	https://doi.org/10.1002/9781118453926.ch36
State	Published - Jul 19 2013

All Science Journal Classification (ASJC) codes

Biochemistry, Genetics and Molecular Biology(all)

Access to Document

10.1002/9781118453926.ch36

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