Abstract
This chapter reviews the underlying organization and function of bone cells and identifies a set of basic structural and kinetic histomorphometric variables. Bone biopsy specimens for histomorphometric examination are ordinarily obtained at the transilial site and shipped to specialized laboratories for processing and microscopic analysis. The chapter outlines an approach to interpretation of findings, with examples from a range of metabolic bone diseases. It describes techniques for obtaining, processing, and analyzing transilial biopsy specimens. The chapter discusses clinical situations in which bone histomorphometry can be useful, and relates histomorphometric measures to data from other methods for assessing bone properties and bone physiology.
| Original language | English (US) |
|---|---|
| Title of host publication | Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism: Eighth Edition |
| Publisher | Wiley Blackwell |
| Pages | 307-316 |
| Number of pages | 10 |
| ISBN (Electronic) | 9781118453926 |
| ISBN (Print) | 9781118453889 |
| DOIs | |
| Publication status | Published - Jul 19 2013 |
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All Science Journal Classification (ASJC) codes
- Biochemistry, Genetics and Molecular Biology(all)