Breast cancer and importance of zygosity determination in triplet sisters

Henry T. Lynch, Patrice Watson, Theresa Conway, Jane Lynch, Jeff Boyd

Research output: Contribution to journalArticle

Abstract

This study is the first to examine the genetic risk in a breast cancer-prone family wherein two of three triplet sisters and their mother manifested breast cancer. The unaffected triplet, the proband, was found to be monozygotic with her deceased sister through DNA testing of tumor blocks and dizygotic to her living affected sister. Genetic counseling implications are discussed.

Original languageEnglish
Pages (from-to)315-317
Number of pages3
JournalBreast Cancer Research and Treatment
Volume36
Issue number3
DOIs
StatePublished - Jan 1995

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Breast Neoplasms
Genetic Counseling
DNA
Neoplasms

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

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Breast cancer and importance of zygosity determination in triplet sisters. / Lynch, Henry T.; Watson, Patrice; Conway, Theresa; Lynch, Jane; Boyd, Jeff.

In: Breast Cancer Research and Treatment, Vol. 36, No. 3, 01.1995, p. 315-317.

Research output: Contribution to journalArticle

Lynch, Henry T. ; Watson, Patrice ; Conway, Theresa ; Lynch, Jane ; Boyd, Jeff. / Breast cancer and importance of zygosity determination in triplet sisters. In: Breast Cancer Research and Treatment. 1995 ; Vol. 36, No. 3. pp. 315-317.
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