Breast cancer and importance of zygosity determination in triplet sisters

Henry T. Lynch; Patrice Watson; Theresa Conway; Jane Lynch; Jeff Boyd

doi:10.1007/BF00713403

Breast cancer and importance of zygosity determination in triplet sisters

Henry T. Lynch, Patrice Watson, Theresa Conway, Jane Lynch, Jeff Boyd

Department of Preventive Medicine

Research output: Contribution to journal › Article

Abstract

This study is the first to examine the genetic risk in a breast cancer-prone family wherein two of three triplet sisters and their mother manifested breast cancer. The unaffected triplet, the proband, was found to be monozygotic with her deceased sister through DNA testing of tumor blocks and dizygotic to her living affected sister. Genetic counseling implications are discussed.

Original language	English (US)
Pages (from-to)	315-317
Number of pages	3
Journal	Breast Cancer Research and Treatment
Volume	36
Issue number	3
DOIs	https://doi.org/10.1007/BF00713403
State	Published - Jan 1 1995

All Science Journal Classification (ASJC) codes

Oncology
Cancer Research

Access to Document

10.1007/BF00713403

Fingerprint Dive into the research topics of 'Breast cancer and importance of zygosity determination in triplet sisters'. Together they form a unique fingerprint.

Cite this

Lynch, H. T., Watson, P., Conway, T., Lynch, J., & Boyd, J. (1995). Breast cancer and importance of zygosity determination in triplet sisters. Breast Cancer Research and Treatment, 36(3), 315-317. https://doi.org/10.1007/BF00713403

@article{1f6f781f4c4e43b1b58af0efbcf48458,

title = "Breast cancer and importance of zygosity determination in triplet sisters",

abstract = "This study is the first to examine the genetic risk in a breast cancer-prone family wherein two of three triplet sisters and their mother manifested breast cancer. The unaffected triplet, the proband, was found to be monozygotic with her deceased sister through DNA testing of tumor blocks and dizygotic to her living affected sister. Genetic counseling implications are discussed.",

author = "Lynch, {Henry T.} and Patrice Watson and Theresa Conway and Jane Lynch and Jeff Boyd",

year = "1995",

month = jan,

day = "1",

doi = "10.1007/BF00713403",

language = "English (US)",

volume = "36",

pages = "315--317",

journal = "Breast Cancer Research and Treatment",

issn = "0167-6806",

publisher = "Springer New York",

number = "3",

}

TY - JOUR

T1 - Breast cancer and importance of zygosity determination in triplet sisters

AU - Lynch, Henry T.

AU - Watson, Patrice

AU - Conway, Theresa

AU - Lynch, Jane

AU - Boyd, Jeff

PY - 1995/1/1

Y1 - 1995/1/1

N2 - This study is the first to examine the genetic risk in a breast cancer-prone family wherein two of three triplet sisters and their mother manifested breast cancer. The unaffected triplet, the proband, was found to be monozygotic with her deceased sister through DNA testing of tumor blocks and dizygotic to her living affected sister. Genetic counseling implications are discussed.

AB - This study is the first to examine the genetic risk in a breast cancer-prone family wherein two of three triplet sisters and their mother manifested breast cancer. The unaffected triplet, the proband, was found to be monozygotic with her deceased sister through DNA testing of tumor blocks and dizygotic to her living affected sister. Genetic counseling implications are discussed.

UR - http://www.scopus.com/inward/record.url?scp=0029144684&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029144684&partnerID=8YFLogxK

U2 - 10.1007/BF00713403

DO - 10.1007/BF00713403

M3 - Article

C2 - 8573714

AN - SCOPUS:0029144684

VL - 36

SP - 315

EP - 317

JO - Breast Cancer Research and Treatment

JF - Breast Cancer Research and Treatment

SN - 0167-6806

IS - 3

ER -