Abstract
Background and objectives Recent understanding of extrarenal production of calcitriol has led to the use of more vitaminD supplementation in CKD populations. This paper reports the effect of cholecalciferol supplementation on calcium absorption. Design, setting, participants, & measurements Paired calcium absorption tests were done before and after 12-13 weeks of 20,000 IUweekly cholecalciferol supplementation in 30 participants with stage 5 CKD on hemodialysis. The study was conducted from April to December of 2011. Calcium absorption was tested with a standardized meal containing 300 mg calcium carbonate intrinsically labeled with 45Ca; 25-hydroxyvitamin D and 1,25- dihydroxyvitamin D were measured. Results 25-Hydroxyvitamin D rose from 14.2 ng/ml (11.5-18.5) at baseline to 49.3 ng/ml (42.3-58.1) at the end of the study (P
| Original language | English |
|---|---|
| Pages (from-to) | 1003-1008 |
| Number of pages | 6 |
| Journal | Clinical journal of the American Society of Nephrology : CJASN |
| Volume | 8 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jun 7 2013 |
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All Science Journal Classification (ASJC) codes
- Nephrology
- Transplantation
- Epidemiology
- Critical Care and Intensive Care Medicine
Cite this
Calcium absorption response to cholecalciferol supplementation in hemodialysis. / Armas, Laura A G; Zena, Mohsen; Lund, Richard; Heaney, Robert P.
In: Clinical journal of the American Society of Nephrology : CJASN, Vol. 8, No. 6, 07.06.2013, p. 1003-1008.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Calcium absorption response to cholecalciferol supplementation in hemodialysis
AU - Armas, Laura A G
AU - Zena, Mohsen
AU - Lund, Richard
AU - Heaney, Robert P.
PY - 2013/6/7
Y1 - 2013/6/7
N2 - Background and objectives Recent understanding of extrarenal production of calcitriol has led to the use of more vitaminD supplementation in CKD populations. This paper reports the effect of cholecalciferol supplementation on calcium absorption. Design, setting, participants, & measurements Paired calcium absorption tests were done before and after 12-13 weeks of 20,000 IUweekly cholecalciferol supplementation in 30 participants with stage 5 CKD on hemodialysis. The study was conducted from April to December of 2011. Calcium absorption was tested with a standardized meal containing 300 mg calcium carbonate intrinsically labeled with 45Ca; 25-hydroxyvitamin D and 1,25- dihydroxyvitamin D were measured. Results 25-Hydroxyvitamin D rose from 14.2 ng/ml (11.5-18.5) at baseline to 49.3 ng/ml (42.3-58.1) at the end of the study (P
AB - Background and objectives Recent understanding of extrarenal production of calcitriol has led to the use of more vitaminD supplementation in CKD populations. This paper reports the effect of cholecalciferol supplementation on calcium absorption. Design, setting, participants, & measurements Paired calcium absorption tests were done before and after 12-13 weeks of 20,000 IUweekly cholecalciferol supplementation in 30 participants with stage 5 CKD on hemodialysis. The study was conducted from April to December of 2011. Calcium absorption was tested with a standardized meal containing 300 mg calcium carbonate intrinsically labeled with 45Ca; 25-hydroxyvitamin D and 1,25- dihydroxyvitamin D were measured. Results 25-Hydroxyvitamin D rose from 14.2 ng/ml (11.5-18.5) at baseline to 49.3 ng/ml (42.3-58.1) at the end of the study (P
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U2 - 10.2215/CJN.08610812
DO - 10.2215/CJN.08610812
M3 - Article
VL - 8
SP - 1003
EP - 1008
JO - Clinical journal of the American Society of Nephrology : CJASN
JF - Clinical journal of the American Society of Nephrology : CJASN
SN - 1555-9041
IS - 6
ER -