Calcium and vitamin D

Robert P. Heaney, Connie M. Weaver

Research output: Contribution to journalReview article

84 Citations (Scopus)

Abstract

Calcium and vitamin D are essential for bone maintenance and for treatment-induced bone augmentation. Deficiencies of both nutrients are very common in the age group most afflicted by osteoporosis. Calcium enhancement of estrogen's effects now have been clearly demonstrated. Additionally, all currently approved bone active agents have been tested only in the presence of extra calcium, and newer anabolic agents create a skeletal need for mineral that will require even higher levels of calcium repletion. Prudent nutritional support for osteoporosis prevention and treatment consists of 30 to 40 mmol Ca/d together with sufficient vitamin D to maintain serum 25(OH)D levels above 80 nmol/L (i.e., ∼25 μg vitamin D/d).

Original languageEnglish
Pages (from-to)181-194
Number of pages14
JournalEndocrinology and Metabolism Clinics of North America
Volume32
Issue number1
DOIs
StatePublished - Feb 2003

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Vitamin D
Calcium
Bone
Bone and Bones
Osteoporosis
Anabolic Agents
Nutritional Support
Nutrients
Minerals
Estrogens
Age Groups
Maintenance
Food
Therapeutics
Serum

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Endocrinology

Cite this

Calcium and vitamin D. / Heaney, Robert P.; Weaver, Connie M.

In: Endocrinology and Metabolism Clinics of North America, Vol. 32, No. 1, 02.2003, p. 181-194.

Research output: Contribution to journalReview article

Heaney, Robert P. ; Weaver, Connie M. / Calcium and vitamin D. In: Endocrinology and Metabolism Clinics of North America. 2003 ; Vol. 32, No. 1. pp. 181-194.
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