Calcium supplements

Practical considerations

R. P. Heaney

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

The preferable source of calcium is a balanced diet, but medicinal supplements are sometimes necessary if patients are to reach desired intakes. A divided dose regimen (4×/d; i.e., with meals and at bedtime) results in substantially greater absorption of a supplement than does l×/d dosing. However, differences in chemical solubility between supplement preparations are of little importance, with calcium carbonate preparations, for example, being absorbed as well or better than some much more highly soluble salts. Gastric acid is not necessary for absorption of even poorly soluble preparations, so long as they are taken with meals. Because typical patients exhibit a wide range of absorption efficiencies, it is desirable to assess absorption fraction before beginning a supplement regimen. (Some patients will need three times as large a dose as others to absorb the same amount of calcium.) Calcium intakes up to at least 62.5 mmol (2500 mg) are safe for virtually all patients.

Original languageEnglish
Pages (from-to)65-71
Number of pages7
JournalOsteoporosis International
Volume1
Issue number2
DOIs
StatePublished - Feb 1991

Fingerprint

Calcium
Meals
Calcium Carbonate
Gastric Acid
Solubility
Salts
Diet

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Calcium supplements : Practical considerations. / Heaney, R. P.

In: Osteoporosis International, Vol. 1, No. 2, 02.1991, p. 65-71.

Research output: Contribution to journalArticle

Heaney, R. P. / Calcium supplements : Practical considerations. In: Osteoporosis International. 1991 ; Vol. 1, No. 2. pp. 65-71.
@article{461bd9b194ba424b9bd4140cdc3f5fa4,
title = "Calcium supplements: Practical considerations",
abstract = "The preferable source of calcium is a balanced diet, but medicinal supplements are sometimes necessary if patients are to reach desired intakes. A divided dose regimen (4×/d; i.e., with meals and at bedtime) results in substantially greater absorption of a supplement than does l×/d dosing. However, differences in chemical solubility between supplement preparations are of little importance, with calcium carbonate preparations, for example, being absorbed as well or better than some much more highly soluble salts. Gastric acid is not necessary for absorption of even poorly soluble preparations, so long as they are taken with meals. Because typical patients exhibit a wide range of absorption efficiencies, it is desirable to assess absorption fraction before beginning a supplement regimen. (Some patients will need three times as large a dose as others to absorb the same amount of calcium.) Calcium intakes up to at least 62.5 mmol (2500 mg) are safe for virtually all patients.",
author = "Heaney, {R. P.}",
year = "1991",
month = "2",
doi = "10.1007/BF01880445",
language = "English",
volume = "1",
pages = "65--71",
journal = "Osteoporosis International",
issn = "0937-941X",
publisher = "Springer London",
number = "2",

}

TY - JOUR

T1 - Calcium supplements

T2 - Practical considerations

AU - Heaney, R. P.

PY - 1991/2

Y1 - 1991/2

N2 - The preferable source of calcium is a balanced diet, but medicinal supplements are sometimes necessary if patients are to reach desired intakes. A divided dose regimen (4×/d; i.e., with meals and at bedtime) results in substantially greater absorption of a supplement than does l×/d dosing. However, differences in chemical solubility between supplement preparations are of little importance, with calcium carbonate preparations, for example, being absorbed as well or better than some much more highly soluble salts. Gastric acid is not necessary for absorption of even poorly soluble preparations, so long as they are taken with meals. Because typical patients exhibit a wide range of absorption efficiencies, it is desirable to assess absorption fraction before beginning a supplement regimen. (Some patients will need three times as large a dose as others to absorb the same amount of calcium.) Calcium intakes up to at least 62.5 mmol (2500 mg) are safe for virtually all patients.

AB - The preferable source of calcium is a balanced diet, but medicinal supplements are sometimes necessary if patients are to reach desired intakes. A divided dose regimen (4×/d; i.e., with meals and at bedtime) results in substantially greater absorption of a supplement than does l×/d dosing. However, differences in chemical solubility between supplement preparations are of little importance, with calcium carbonate preparations, for example, being absorbed as well or better than some much more highly soluble salts. Gastric acid is not necessary for absorption of even poorly soluble preparations, so long as they are taken with meals. Because typical patients exhibit a wide range of absorption efficiencies, it is desirable to assess absorption fraction before beginning a supplement regimen. (Some patients will need three times as large a dose as others to absorb the same amount of calcium.) Calcium intakes up to at least 62.5 mmol (2500 mg) are safe for virtually all patients.

UR - http://www.scopus.com/inward/record.url?scp=0026102844&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026102844&partnerID=8YFLogxK

U2 - 10.1007/BF01880445

DO - 10.1007/BF01880445

M3 - Article

VL - 1

SP - 65

EP - 71

JO - Osteoporosis International

JF - Osteoporosis International

SN - 0937-941X

IS - 2

ER -