Abstract
The authors studied a kindred among whom adenocarcinoma of the colon and endometrium and multiple primary malignant neoplasms have occurred with increased frequency through three generations. These findings fulfill the criteria for the cancer family syndrome which includes: increased frequency of adenocarcinoma, particularly of colon and endometrium; increased frequency of multiple primary malignant neoplasms; early age of onset of cancer, when compared to expectations from the general population; and vertical transmission of cancer consistent with autosomal dominant mode of genetic transmission.
| Original language | English |
|---|---|
| Pages (from-to) | 33-37 |
| Number of pages | 5 |
| Journal | The Nebraska medical journal |
| Volume | 60 |
| Issue number | 2 |
| State | Published - 1975 |
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All Science Journal Classification (ASJC) codes
- Medicine(all)
Cite this
Cancer genetics, genetic counseling, and cancer control. / Lynch, Henry T.; Lynch, J. F.
In: The Nebraska medical journal, Vol. 60, No. 2, 1975, p. 33-37.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cancer genetics, genetic counseling, and cancer control
AU - Lynch, Henry T.
AU - Lynch, J. F.
PY - 1975
Y1 - 1975
N2 - The authors studied a kindred among whom adenocarcinoma of the colon and endometrium and multiple primary malignant neoplasms have occurred with increased frequency through three generations. These findings fulfill the criteria for the cancer family syndrome which includes: increased frequency of adenocarcinoma, particularly of colon and endometrium; increased frequency of multiple primary malignant neoplasms; early age of onset of cancer, when compared to expectations from the general population; and vertical transmission of cancer consistent with autosomal dominant mode of genetic transmission.
AB - The authors studied a kindred among whom adenocarcinoma of the colon and endometrium and multiple primary malignant neoplasms have occurred with increased frequency through three generations. These findings fulfill the criteria for the cancer family syndrome which includes: increased frequency of adenocarcinoma, particularly of colon and endometrium; increased frequency of multiple primary malignant neoplasms; early age of onset of cancer, when compared to expectations from the general population; and vertical transmission of cancer consistent with autosomal dominant mode of genetic transmission.
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UR - http://www.scopus.com/inward/citedby.url?scp=0016659827&partnerID=8YFLogxK
M3 - Article
VL - 60
SP - 33
EP - 37
JO - The Nebraska medical journal
JF - The Nebraska medical journal
SN - 0091-6730
IS - 2
ER -