Cancer genetics, genetic counseling, and cancer control

H. T. Lynch, J. F. Lynch

Research output: Contribution to journalArticlepeer-review


The authors studied a kindred among whom adenocarcinoma of the colon and endometrium and multiple primary malignant neoplasms have occurred with increased frequency through three generations. These findings fulfill the criteria for the cancer family syndrome which includes: increased frequency of adenocarcinoma, particularly of colon and endometrium; increased frequency of multiple primary malignant neoplasms; early age of onset of cancer, when compared to expectations from the general population; and vertical transmission of cancer consistent with autosomal dominant mode of genetic transmission.

Original languageEnglish (US)
Pages (from-to)33-37
Number of pages5
Issue number2
StatePublished - Dec 1 1975

All Science Journal Classification (ASJC) codes

  • Medicine(all)


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