Cancer resistance

part II

Henry T. Lynch, H. A. Guirgis

Research output: Contribution to journalArticle

Abstract

The authors attempted to show that certain families in the general population show a profound paucity of cancer. Furthermore they demonstrated that a sizeable proportion of the normal population (approximately 46%) show an absence of cancer amongst first degree relatives, while a minority of the population (approximately 7%) are cancer prone, as evidenced by 3 or more occurrences of cancer in first degree relatives. These findings have implications for research in carcinogenesis, in that it may be as important to know why certain members of the population are at reduced risk for cancer as it is to know why those in the population are remarkably cancer prone. Cancer control implications also exist in that an important risk factor to be considered in any cancer control program is family history. This even applies to other obvious risk factors such as cigarette smoking, wherein it is well known that family history of lung cancer significantly increases the likelihood of the cigarette smoker developing lung cancer. Finally, these studies indicate a wide range of cancer susceptibility in humans, a phenomenon that is a function of both genetic and non genetic factors, and which is very similar to findings observed at the infrahuman level.

Original languageEnglish
Pages (from-to)192-196
Number of pages5
JournalThe Nebraska medical journal
Volume59
Issue number6
StatePublished - 1974

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Neoplasms
Population
Lung Neoplasms
Tobacco Products
Carcinogenesis
Smoking
Research

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Lynch, H. T., & Guirgis, H. A. (1974). Cancer resistance: part II. The Nebraska medical journal, 59(6), 192-196.

Cancer resistance : part II. / Lynch, Henry T.; Guirgis, H. A.

In: The Nebraska medical journal, Vol. 59, No. 6, 1974, p. 192-196.

Research output: Contribution to journalArticle

Lynch, HT & Guirgis, HA 1974, 'Cancer resistance: part II', The Nebraska medical journal, vol. 59, no. 6, pp. 192-196.
Lynch, Henry T. ; Guirgis, H. A. / Cancer resistance : part II. In: The Nebraska medical journal. 1974 ; Vol. 59, No. 6. pp. 192-196.
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