Abstract
Leukocyte adherence to endothelium represents one of the early responses to injury. Although the underlying mechanisms of atherosclerosis and intimal hyperplasia remain unclear, monocytes/macrophages are associated with this phenomenon. Since cigarette smoking has been identified as a major risk factor for cardiovascular disease, we examined the effects of chronic cigarette smoking on human leukocyte adherence (monocytes, lymphocytes, and neutrophils) to cultured human umbilical vein endothelial cells (HUVEC's) in vitro. Among the cells, the basal adherence of monocytes only was significantly elevated in the smoking group (p
| Original language | English |
|---|---|
| Pages (from-to) | 929-934 |
| Number of pages | 6 |
| Journal | Biochemical and Biophysical Research Communications |
| Volume | 203 |
| Issue number | 2 |
| DOIs | |
| State | Published - 1994 |
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All Science Journal Classification (ASJC) codes
- Biochemistry
- Biophysics
- Molecular Biology
Cite this
Cigarette smoking increases monocyte adherence to cultured endothelial cell monolayer. / Dovgan, P. S.; Edwards, J. D.; Zhan, X.; Wilde, M.; Agrawal, Devendra K.
In: Biochemical and Biophysical Research Communications, Vol. 203, No. 2, 1994, p. 929-934.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cigarette smoking increases monocyte adherence to cultured endothelial cell monolayer
AU - Dovgan, P. S.
AU - Edwards, J. D.
AU - Zhan, X.
AU - Wilde, M.
AU - Agrawal, Devendra K.
PY - 1994
Y1 - 1994
N2 - Leukocyte adherence to endothelium represents one of the early responses to injury. Although the underlying mechanisms of atherosclerosis and intimal hyperplasia remain unclear, monocytes/macrophages are associated with this phenomenon. Since cigarette smoking has been identified as a major risk factor for cardiovascular disease, we examined the effects of chronic cigarette smoking on human leukocyte adherence (monocytes, lymphocytes, and neutrophils) to cultured human umbilical vein endothelial cells (HUVEC's) in vitro. Among the cells, the basal adherence of monocytes only was significantly elevated in the smoking group (p
AB - Leukocyte adherence to endothelium represents one of the early responses to injury. Although the underlying mechanisms of atherosclerosis and intimal hyperplasia remain unclear, monocytes/macrophages are associated with this phenomenon. Since cigarette smoking has been identified as a major risk factor for cardiovascular disease, we examined the effects of chronic cigarette smoking on human leukocyte adherence (monocytes, lymphocytes, and neutrophils) to cultured human umbilical vein endothelial cells (HUVEC's) in vitro. Among the cells, the basal adherence of monocytes only was significantly elevated in the smoking group (p
UR - http://www.scopus.com/inward/record.url?scp=0028133433&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028133433&partnerID=8YFLogxK
U2 - 10.1006/bbrc.1994.2271
DO - 10.1006/bbrc.1994.2271
M3 - Article
VL - 203
SP - 929
EP - 934
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
SN - 0006-291X
IS - 2
ER -