Clinical Features and Surgical Treatment of Schwannoma Affecting the Base of the Tongue: A Systematic Review

Jenna Lamendola Sitenga, Gregory Alan Aird, Austin Nguyen, Adam Vaudreuil, Christopher Huerter

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Introduction Schwannomas of the head and neck account for 25–40% of all cases, with presentation at the base of the tongue as the most frequent site for intraoral tumors. Objectives Here, a systematic review was conducted to include 15 cases of patients with schwannoma of the base of the tongue. Data Synthesis Most patients presented with a single, painless, well-encapsulated nodule at the base of the tongue. These nodules were slow-growing, with an average of 13.3 months from onset to presentation. Most cases were accompanied by airway obstruction, indicated by symptoms of dysphagia, dysarthria, snoring, and sleep apnea. Overall, the histological studies were consistent with a benign schwannoma with a palisading Antoni A and Antoni B pattern without malignant changes in cell morphology. These tumors were treated via complete surgical excision, and all cases achieved full remission by final follow-up. Conclusion Surgical removal is the primary mode of treatment with excellent postoperative prognosis and rare instances of recurrence. Given the rarity of this tumor, this review of available case studies serves to comprehensively describe clinical presentation and surgical treatment approaches to tongue base schwannoma.

Original languageEnglish (US)
JournalInternational Archives of Otorhinolaryngology
DOIs
StateAccepted/In press - Dec 21 2016

Fingerprint

Neurilemmoma
Tongue
Dysarthria
Neoplasms
Snoring
Sleep Apnea Syndromes
Airway Obstruction
Therapeutics
Deglutition Disorders
Neck
Head
Recurrence

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology

Cite this

Clinical Features and Surgical Treatment of Schwannoma Affecting the Base of the Tongue : A Systematic Review. / Sitenga, Jenna Lamendola; Aird, Gregory Alan; Nguyen, Austin; Vaudreuil, Adam; Huerter, Christopher.

In: International Archives of Otorhinolaryngology, 21.12.2016.

Research output: Contribution to journalArticle

@article{ed5d05c692804061b2e590559c7c1ace,
title = "Clinical Features and Surgical Treatment of Schwannoma Affecting the Base of the Tongue: A Systematic Review",
abstract = "Introduction Schwannomas of the head and neck account for 25–40{\%} of all cases, with presentation at the base of the tongue as the most frequent site for intraoral tumors. Objectives Here, a systematic review was conducted to include 15 cases of patients with schwannoma of the base of the tongue. Data Synthesis Most patients presented with a single, painless, well-encapsulated nodule at the base of the tongue. These nodules were slow-growing, with an average of 13.3 months from onset to presentation. Most cases were accompanied by airway obstruction, indicated by symptoms of dysphagia, dysarthria, snoring, and sleep apnea. Overall, the histological studies were consistent with a benign schwannoma with a palisading Antoni A and Antoni B pattern without malignant changes in cell morphology. These tumors were treated via complete surgical excision, and all cases achieved full remission by final follow-up. Conclusion Surgical removal is the primary mode of treatment with excellent postoperative prognosis and rare instances of recurrence. Given the rarity of this tumor, this review of available case studies serves to comprehensively describe clinical presentation and surgical treatment approaches to tongue base schwannoma.",
author = "Sitenga, {Jenna Lamendola} and Aird, {Gregory Alan} and Austin Nguyen and Adam Vaudreuil and Christopher Huerter",
year = "2016",
month = "12",
day = "21",
doi = "10.1055/s-0037-1598609",
language = "English (US)",
journal = "International Archives of Otorhinolaryngology",
issn = "1809-9777",
publisher = "Thieme Medical Publishers",

}

TY - JOUR

T1 - Clinical Features and Surgical Treatment of Schwannoma Affecting the Base of the Tongue

T2 - A Systematic Review

AU - Sitenga, Jenna Lamendola

AU - Aird, Gregory Alan

AU - Nguyen, Austin

AU - Vaudreuil, Adam

AU - Huerter, Christopher

PY - 2016/12/21

Y1 - 2016/12/21

N2 - Introduction Schwannomas of the head and neck account for 25–40% of all cases, with presentation at the base of the tongue as the most frequent site for intraoral tumors. Objectives Here, a systematic review was conducted to include 15 cases of patients with schwannoma of the base of the tongue. Data Synthesis Most patients presented with a single, painless, well-encapsulated nodule at the base of the tongue. These nodules were slow-growing, with an average of 13.3 months from onset to presentation. Most cases were accompanied by airway obstruction, indicated by symptoms of dysphagia, dysarthria, snoring, and sleep apnea. Overall, the histological studies were consistent with a benign schwannoma with a palisading Antoni A and Antoni B pattern without malignant changes in cell morphology. These tumors were treated via complete surgical excision, and all cases achieved full remission by final follow-up. Conclusion Surgical removal is the primary mode of treatment with excellent postoperative prognosis and rare instances of recurrence. Given the rarity of this tumor, this review of available case studies serves to comprehensively describe clinical presentation and surgical treatment approaches to tongue base schwannoma.

AB - Introduction Schwannomas of the head and neck account for 25–40% of all cases, with presentation at the base of the tongue as the most frequent site for intraoral tumors. Objectives Here, a systematic review was conducted to include 15 cases of patients with schwannoma of the base of the tongue. Data Synthesis Most patients presented with a single, painless, well-encapsulated nodule at the base of the tongue. These nodules were slow-growing, with an average of 13.3 months from onset to presentation. Most cases were accompanied by airway obstruction, indicated by symptoms of dysphagia, dysarthria, snoring, and sleep apnea. Overall, the histological studies were consistent with a benign schwannoma with a palisading Antoni A and Antoni B pattern without malignant changes in cell morphology. These tumors were treated via complete surgical excision, and all cases achieved full remission by final follow-up. Conclusion Surgical removal is the primary mode of treatment with excellent postoperative prognosis and rare instances of recurrence. Given the rarity of this tumor, this review of available case studies serves to comprehensively describe clinical presentation and surgical treatment approaches to tongue base schwannoma.

UR - http://www.scopus.com/inward/record.url?scp=85012920297&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85012920297&partnerID=8YFLogxK

U2 - 10.1055/s-0037-1598609

DO - 10.1055/s-0037-1598609

M3 - Article

AN - SCOPUS:85012920297

JO - International Archives of Otorhinolaryngology

JF - International Archives of Otorhinolaryngology

SN - 1809-9777

ER -