Colorectal cancer in a nuclear family - Familial or hereditary?

Henry T. Lynch, Robert Joseph Fitzgibbons, Joseph Marcus, James McGill, Gerard J. Voorhees, Jane F. Lynch

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Because of the high incidence of colorectal cancer, familial aggregations of this disease are common. Differentiation between etiologies contributing to familial clustering (which may have resulted either from common environmental exposure or from mere chance) and primary genetic factors may prove vexing to the physician. This report deals with the myriad problems encountered when attempting to make such etiologic distinctions in order to provide appropriate surveillance and management, based upon tumor spectrum and natural history, for patients at increased cancer risk.

Original languageEnglish
Pages (from-to)310-316
Number of pages7
JournalDiseases of the Colon and Rectum
Volume28
Issue number5
DOIs
StatePublished - May 1985

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Nuclear Family
Colorectal Neoplasms
Environmental Exposure
Natural History
Cluster Analysis
Neoplasms
Physicians
Incidence

All Science Journal Classification (ASJC) codes

  • Gastroenterology

Cite this

Colorectal cancer in a nuclear family - Familial or hereditary? / Lynch, Henry T.; Fitzgibbons, Robert Joseph; Marcus, Joseph; McGill, James; Voorhees, Gerard J.; Lynch, Jane F.

In: Diseases of the Colon and Rectum, Vol. 28, No. 5, 05.1985, p. 310-316.

Research output: Contribution to journalArticle

Lynch, Henry T. ; Fitzgibbons, Robert Joseph ; Marcus, Joseph ; McGill, James ; Voorhees, Gerard J. ; Lynch, Jane F. / Colorectal cancer in a nuclear family - Familial or hereditary?. In: Diseases of the Colon and Rectum. 1985 ; Vol. 28, No. 5. pp. 310-316.
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