Community-onset disease caused by Citrobacter freundii producing a novel CTX-M β-lactamase, CTX-M-30, in Canada

Baha Abdalhamid, J. D D Pitout, Ellen S. Moland, Nancy D. Hanson

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Strains of Citrobacter freundii intermediate to cefotaxime but sensitive to ceftazidime were isolated from four different patients in Canada. Sequencing of PCR products by use of CTX-M-specific primers revealed a new combination of four amino acid substitutions. This new gene was designated bla CTX-M-30 and was encoded on a 3-kb plasmid. The pI of CTX-M-30 was 8.0.

Original languageEnglish
Pages (from-to)4435-4437
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume48
Issue number11
DOIs
StatePublished - Nov 2004

Fingerprint

Citrobacter freundii
Ceftazidime
Cefotaxime
Amino Acid Substitution
Canada
Plasmids
Polymerase Chain Reaction
Genes

All Science Journal Classification (ASJC) codes

  • Pharmacology (medical)

Cite this

Community-onset disease caused by Citrobacter freundii producing a novel CTX-M β-lactamase, CTX-M-30, in Canada. / Abdalhamid, Baha; Pitout, J. D D; Moland, Ellen S.; Hanson, Nancy D.

In: Antimicrobial Agents and Chemotherapy, Vol. 48, No. 11, 11.2004, p. 4435-4437.

Research output: Contribution to journalArticle

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