Comparative analysis of conjugative plasmids mediating gentamicin resistance in Staphylococcus aureus

Richard V. Goering, E. A. Ruff

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Abstract

Five gentamicin-resistant clinical isolates of Staphylococcus aureus were found to contain self-transmissible plasmids of 32 to 37 megadaltons in size. Restriction endonuclease digests of the plasmids were markedly similar to those of reference plasmids of unrelated geographical origin, thus suggesting the significant contribution of common conjugal plasmids to the emergence of gentamicin resistance in S. aureus populations.

Original languageEnglish
Pages (from-to)450-452
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume24
Issue number3
StatePublished - 1983

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Gentamicins
Staphylococcus aureus
Plasmids
DNA Restriction Enzymes
Population

All Science Journal Classification (ASJC) codes

  • Pharmacology (medical)

Cite this

Comparative analysis of conjugative plasmids mediating gentamicin resistance in Staphylococcus aureus. / Goering, Richard V.; Ruff, E. A.

In: Antimicrobial Agents and Chemotherapy, Vol. 24, No. 3, 1983, p. 450-452.

Research output: Contribution to journalArticle

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