Comparative analysis of conjugative plasmids mediating gentamicin resistance in Staphylococcus aureus

R. V. Goering, E. A. Ruff

Research output: Contribution to journalArticle

42 Scopus citations

Abstract

Five gentamicin-resistant clinical isolates of Staphylococcus aureus were found to contain self-transmissible plasmids of 32 to 37 megadaltons in size. Restriction endonuclease digests of the plasmids were markedly similar to those of reference plasmids of unrelated geographical origin, thus suggesting the significant contribution of common conjugal plasmids to the emergence of gentamicin resistance in S. aureus populations.

Original languageEnglish (US)
Pages (from-to)450-452
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume24
Issue number3
DOIs
StatePublished - Jan 1 1983

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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