Comparison of cardiovascular risk calculation tools in pharmacy practice

Nicole D. White, Thomas L. Lenz, Maryann Z. Skrabal, Michele A. Faulkner, Jessica J. Skradski, Leslie A. Southard, Derek E. Popken

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Objective: To examine the use of various cardiovascular disease (CVD) risk estimation calculators in pharmacy practice. Design: Longitudinal cohort study. Setting: Midwestern university worksite from August 2008 through May 2012. Participants: University employees with hypertension, dyslipidemia, and diabetes. Intervention: Risk estimation calculators were applied to data from a pharmacist- run chronic disease management program. Main outcome measure: Difference in estimated CVD risk from multiple estimation calculators. Results: At baseline and 12 months, non-lab-based tools reported significantly higher 10-year CVD risk percentages compared with lab-based tools among the same cohort of patients (10.63% vs. 8.71% at baseline, P <0.001; 9.34% vs. 7.31% at 12 months, P <0.001). In addition, the electronic version of 10-year CVD risk reported significantly higher values than the paper version when applied to the same patient cohort (7.31% vs. 6.60% at 12 months, P = 0.018). Conclusion: CVD risk estimation tools report significantly different values and are not interchangeable. Pharmacists using non-lab-based tools should expect significantly higher risk estimates than estimates derived from lab-based tools and therefore should use the same version of the estimation tool over the long term.

Original languageEnglish (US)
Pages (from-to)408-413
Number of pages6
JournalJournal of the American Pharmacists Association
Issue number4
StatePublished - Jan 1 2013

All Science Journal Classification (ASJC) codes

  • Pharmacology (nursing)
  • Pharmacy
  • Pharmacology


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