Comparison of percutaneous device closure versus surgical closure of peri-membranous ventricular septal defects: A systematic review and meta-analysis

Alok Saurav, Manu Kaushik, Venkata Mahesh Alla, Michael D. White, Ruby Satpathy, Thomas Lanspa, Aryan N. Mooss, Michael G. Delcore

Research output: Contribution to journalReview article

24 Scopus citations


Background While percutaneous device closure (PDC) is a first-line therapy for isolated muscular ventricular septal defects (mVSD), surgery is still the preferred approach for peri-membranous ventricular septal defects (pmVSD). Objective We sought to compare the outcomes of percutaneous versus open surgical closure of pmVSDs. Methods PubMed, Cochrane Library, and Web of Science databases were searched through October 15, 2014 for English language studies comparing outcomes of PDC with surgical closure of pmVSDs. Study quality, publication bias, and heterogeneity were assessed. A meta-analysis of selected studies was performed using a random effects model. Comparison was done for early (

Original languageEnglish (US)
Pages (from-to)1048-1056
Number of pages9
JournalCatheterization and Cardiovascular Interventions
Issue number6
StatePublished - Nov 15 2015


All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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