Comparison of ultrasonically nebulized distilled water and cold-air hyperventilation challenges in asthmatic patients

T. S. Lemire, R. J. Hopp, Againdra K. Bewtra, N. M. Nair, R. G. Townley

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Cold-air hyperventilation (CAHC) and ultrasonically nebulized distilled water (UNDW) challenges were compared in 11 asthmatic patients who were moderately sensitive to methacholine. The challenges were performed on two separate days within one week of each other. Baseline FEV1 on each test day was >70 percent of predicted. Ten of 11 subjects' FEV1 decreased at least 15 percent, and nine of 11 decreased at least 20 percent during the UNDW. Ten of 11 subjects' FEV1 decreased at least 10 percent, and eight of 11 decreased at least 15 percent during the CAHC. Using a Spearman rank coefficient, the results of the CAHC and UNDW were compared; the best correlation between the various CAHC and UNDW measurements equaled only 0.51. The correlation between UNDW and CAHC suggests that the mechanism of action of each challenge may be different.

Original languageEnglish
Pages (from-to)958-961
Number of pages4
JournalChest
Volume95
Issue number5
StatePublished - 1989

Fingerprint

Hyperventilation
Air
Water
Methacholine Chloride

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine

Cite this

Comparison of ultrasonically nebulized distilled water and cold-air hyperventilation challenges in asthmatic patients. / Lemire, T. S.; Hopp, R. J.; Bewtra, Againdra K.; Nair, N. M.; Townley, R. G.

In: Chest, Vol. 95, No. 5, 1989, p. 958-961.

Research output: Contribution to journalArticle

Lemire, T. S. ; Hopp, R. J. ; Bewtra, Againdra K. ; Nair, N. M. ; Townley, R. G. / Comparison of ultrasonically nebulized distilled water and cold-air hyperventilation challenges in asthmatic patients. In: Chest. 1989 ; Vol. 95, No. 5. pp. 958-961.
@article{16769e925be24fcfa67eb230ecf5fb8e,
title = "Comparison of ultrasonically nebulized distilled water and cold-air hyperventilation challenges in asthmatic patients",
abstract = "Cold-air hyperventilation (CAHC) and ultrasonically nebulized distilled water (UNDW) challenges were compared in 11 asthmatic patients who were moderately sensitive to methacholine. The challenges were performed on two separate days within one week of each other. Baseline FEV1 on each test day was >70 percent of predicted. Ten of 11 subjects' FEV1 decreased at least 15 percent, and nine of 11 decreased at least 20 percent during the UNDW. Ten of 11 subjects' FEV1 decreased at least 10 percent, and eight of 11 decreased at least 15 percent during the CAHC. Using a Spearman rank coefficient, the results of the CAHC and UNDW were compared; the best correlation between the various CAHC and UNDW measurements equaled only 0.51. The correlation between UNDW and CAHC suggests that the mechanism of action of each challenge may be different.",
author = "Lemire, {T. S.} and Hopp, {R. J.} and Bewtra, {Againdra K.} and Nair, {N. M.} and Townley, {R. G.}",
year = "1989",
language = "English",
volume = "95",
pages = "958--961",
journal = "Chest",
issn = "0012-3692",
publisher = "American College of Chest Physicians",
number = "5",

}

TY - JOUR

T1 - Comparison of ultrasonically nebulized distilled water and cold-air hyperventilation challenges in asthmatic patients

AU - Lemire, T. S.

AU - Hopp, R. J.

AU - Bewtra, Againdra K.

AU - Nair, N. M.

AU - Townley, R. G.

PY - 1989

Y1 - 1989

N2 - Cold-air hyperventilation (CAHC) and ultrasonically nebulized distilled water (UNDW) challenges were compared in 11 asthmatic patients who were moderately sensitive to methacholine. The challenges were performed on two separate days within one week of each other. Baseline FEV1 on each test day was >70 percent of predicted. Ten of 11 subjects' FEV1 decreased at least 15 percent, and nine of 11 decreased at least 20 percent during the UNDW. Ten of 11 subjects' FEV1 decreased at least 10 percent, and eight of 11 decreased at least 15 percent during the CAHC. Using a Spearman rank coefficient, the results of the CAHC and UNDW were compared; the best correlation between the various CAHC and UNDW measurements equaled only 0.51. The correlation between UNDW and CAHC suggests that the mechanism of action of each challenge may be different.

AB - Cold-air hyperventilation (CAHC) and ultrasonically nebulized distilled water (UNDW) challenges were compared in 11 asthmatic patients who were moderately sensitive to methacholine. The challenges were performed on two separate days within one week of each other. Baseline FEV1 on each test day was >70 percent of predicted. Ten of 11 subjects' FEV1 decreased at least 15 percent, and nine of 11 decreased at least 20 percent during the UNDW. Ten of 11 subjects' FEV1 decreased at least 10 percent, and eight of 11 decreased at least 15 percent during the CAHC. Using a Spearman rank coefficient, the results of the CAHC and UNDW were compared; the best correlation between the various CAHC and UNDW measurements equaled only 0.51. The correlation between UNDW and CAHC suggests that the mechanism of action of each challenge may be different.

UR - http://www.scopus.com/inward/record.url?scp=0024391717&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024391717&partnerID=8YFLogxK

M3 - Article

C2 - 2495907

AN - SCOPUS:0024391717

VL - 95

SP - 958

EP - 961

JO - Chest

JF - Chest

SN - 0012-3692

IS - 5

ER -