Abstract
Enantiomerically pure steroid intermediates (S)-1 and (S)-(+)-2 of natural absolute configuration have been prepared with complete asymmetric induction during zinc dibromide mediated vinylmagnesium bromide conjugate addition to enantiomerically pure, crystalline, stable cyclopentenone sulfoxide (S)-(+)-5, which has been prepared on a 10-g scale.
| Original language | English |
|---|---|
| Pages (from-to) | 5244-5246 |
| Number of pages | 3 |
| Journal | Journal of Organic Chemistry |
| Volume | 46 |
| Issue number | 25 |
| State | Published - 1981 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Organic Chemistry
Cite this
Complete asymmetric induction in synthesis of enantiomerically pure steroid intermediates of natural configuration. / Posner, Gary H.; Hulce, Martin; Mallamo, John P.; Drexler, Steven A.; Clardy, Jon.
In: Journal of Organic Chemistry, Vol. 46, No. 25, 1981, p. 5244-5246.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Complete asymmetric induction in synthesis of enantiomerically pure steroid intermediates of natural configuration
AU - Posner, Gary H.
AU - Hulce, Martin
AU - Mallamo, John P.
AU - Drexler, Steven A.
AU - Clardy, Jon
PY - 1981
Y1 - 1981
N2 - Enantiomerically pure steroid intermediates (S)-1 and (S)-(+)-2 of natural absolute configuration have been prepared with complete asymmetric induction during zinc dibromide mediated vinylmagnesium bromide conjugate addition to enantiomerically pure, crystalline, stable cyclopentenone sulfoxide (S)-(+)-5, which has been prepared on a 10-g scale.
AB - Enantiomerically pure steroid intermediates (S)-1 and (S)-(+)-2 of natural absolute configuration have been prepared with complete asymmetric induction during zinc dibromide mediated vinylmagnesium bromide conjugate addition to enantiomerically pure, crystalline, stable cyclopentenone sulfoxide (S)-(+)-5, which has been prepared on a 10-g scale.
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UR - http://www.scopus.com/inward/citedby.url?scp=0040988661&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0040988661
VL - 46
SP - 5244
EP - 5246
JO - Journal of Organic Chemistry
JF - Journal of Organic Chemistry
SN - 0022-3263
IS - 25
ER -