Abstract
Enantiomerically pure steroid intermediates (S)-1 and (S)-(+)-2 of natural absolute configuration have been prepared with complete asymmetric induction during zinc dibromide mediated vinylmagnesium bromide conjugate addition to enantiomerically pure, crystalline, stable cyclopentenone sulfoxide (S)-(+)-5, which has been prepared on a 10-g scale.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 5244-5246 |
| Number of pages | 3 |
| Journal | Journal of Organic Chemistry |
| Volume | 46 |
| Issue number | 25 |
| DOIs | |
| State | Published - Dec 1981 |
| Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Organic Chemistry
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Cite this
Posner, G. H., Hulee, M., Mallamo, J. P., Drexler, S. A., & Clardy, J. (1981). Complete Asymmetric Induction in Synthesis of Enantiomerically Pure Steroid Intermediates of Natural Configuration. Journal of Organic Chemistry, 46(25), 5244-5246. https://doi.org/10.1021/jo00338a047